Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Susan L Hafenstein"'
Autor:
Matthew D Lauver, Daniel J Goetschius, Colleen S Netherby-Winslow, Katelyn N Ayers, Ge Jin, Daniel G Haas, Elizabeth L Frost, Sung Hyun Cho, Carol M Bator, Stephanie M Bywaters, Neil D Christensen, Susan L Hafenstein, Aron E Lukacher
Publikováno v:
eLife, Vol 9 (2020)
JCPyV polyomavirus, a member of the human virome, causes progressive multifocal leukoencephalopathy (PML), an oft-fatal demyelinating brain disease in individuals receiving immunomodulatory therapies. Mutations in the major viral capsid protein, VP1,
Externí odkaz:
https://doaj.org/article/49ff0ad1d7a649d79e8ecf95bda3fe2f
Autor:
Hyunwook Lee, Ruben Assaraf, Suriyasri Subramanian, Dan Goetschius, Jan Bieri, Nadia M. DiNunno, Remo Leisi, Carol M. Bator, Susan L. Hafenstein, Carlos Ros
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The lack of a permissive cell culture system has limited high-resolution structures of parvovirus B19 (B19V) to virus-like particles (VLPs). In this study, we present the atomic resolution structure (2.2 Å) of authentic B19V purified from a
Externí odkaz:
https://doaj.org/article/3a9c0db732b04c84b64b65933cdc26b0
Autor:
Chuan Xiao, Yurii G Kuznetsov, Siyang Sun, Susan L Hafenstein, Victor A Kostyuchenko, Paul R Chipman, Marie Suzan-Monti, Didier Raoult, Alexander McPherson, Michael G Rossmann
Publikováno v:
PLoS Biology, Vol 7, Iss 4, p e92 (2009)
Mimivirus is the largest known virus whose genome and physical size are comparable to some small bacteria, blurring the boundary between a virus and a cell. Structural studies of Mimivirus have been difficult because of its size and long surface fibe
Externí odkaz:
https://doaj.org/article/e4761cd9d7c34ca48f50e686e1dd403e
Autor:
Devanshi R. Patel, Allen M. Minns, Derek G. Sim, Cassandra J. Field, Abigail E. Kerr, Talia A. Heinly, Erin H. Luley, Randall M. Rossi, Carol M. Bator, Ibrahim M. Moustafa, Elizabeth B. Norton, Susan L. Hafenstein, Scott E. Lindner, Troy C. Sutton
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTMultiple vaccines have been developed and licensed for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). While these vaccines reduce disease severity, they do not prevent infection. To prevent infection and limit transmission, vac
Externí odkaz:
https://doaj.org/article/55f1a1bf25284935bbdcb7a25dab70bd
Autor:
Andrew J. Charnesky, Julia E. Faust, Hyunwook Lee, Rama Devudu Puligedda, Daniel J. Goetschius, Nadia M. DiNunno, Vaskar Thapa, Carol M. Bator, Sung Hyun (Joseph) Cho, Rahnuma Wahid, Kutub Mahmood, Scott Dessain, Konstantin M. Chumakov, Amy Rosenfeld, Susan L. Hafenstein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Global eradication of poliovirus remains elusive, and it is critical to develop next generation vaccines and antivirals. In support of this goal, we map the epitope of human monoclonal antibody 9H2 which is able to neutralize the three serot
Externí odkaz:
https://doaj.org/article/9fd2243b86754c1196621e07354a248f
Autor:
Samantha R. Hartmann, Andrew J. Charnesky, Simon P. Früh, Robert A. López-Astacio, Wendy S. Weichert, Nadia DiNunno, Sung Hung Cho, Carol M. Bator, Colin R. Parrish, Susan L. Hafenstein
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Canine parvovirus (CPV) is an important pathogen that emerged by cross-species transmission to cause severe disease in dogs. To understand the host immune response to vaccination, sera from dogs immunized with parvovirus are obtained, the po
Externí odkaz:
https://doaj.org/article/2efb5d4d0c334371b3766473a0aa6b1f
Autor:
Samantha R. Hartmann, Daniel J. Goetschius, Jiafen Hu, Joshua J. Graff, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein
Publikováno v:
Viruses, Vol 13, Iss 10, p 2023 (2021)
Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. However, studies have been hampered due to restricted tropism that makes production and purification of high titer virus problematic. This issue has
Externí odkaz:
https://doaj.org/article/fc77a8772a78492a91c40dfcca533a5e
Autor:
Robert A. López-Astacio, Oluwafemi F. Adu, Daniel J. Goetschius, Hyunwook Lee, Wendy S. Weichert, Brian R. Wasik, Simon P. Frueh, Brynn K. Alford, Ian E.H. Voorhees, Joseph F. Flint, Sarah Saddoris, Laura B. Goodman, Edward C. Holmes, Susan L. Hafenstein, Colin R. Parrish
Publikováno v:
bioRxiv
Canine parvovirus (CPV) is a small non-enveloped single-stranded DNA virus that causes serious diseases in dogs worldwide. The original strain of the virus (CPV-2) emerged in dogs during the late-1970s due to a host range switch of a virus similar to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2accdbf1599fd60b50108daaf84f01
https://doi.org/10.1128/jvi.00090-23
https://doi.org/10.1128/jvi.00090-23
Publikováno v:
J Virol
Ubiquitous and abundant in ecosystems and microbiomes, gokushoviruses constitute a Microviridae subfamily, distantly related to bacteriophages ΦX174, α3, and G4. A high-resolution cryo-EM structure of gokushovirus ΦEC6098 was determined, and the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b710229b3d0badeea6af1328012acde
https://doi.org/10.1128/jvi.00990-22
https://doi.org/10.1128/jvi.00990-22
Autor:
Joyce, Jose, Susan L, Hafenstein
Publikováno v:
Current Opinion in Virology. 54:101230
Asymmetric structural elements are typically not readily visualized in icosahedral viruses that have other obvious symmetrical features and most asymmetry has gone unresolved for decades. Asymmetric features may be incorporated during assembly or mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcc4d31df4bffb445082255b373c6a3
https://doi.org/10.1016/j.coviro.2022.101230
https://doi.org/10.1016/j.coviro.2022.101230