Výsledky vyhledávání - "Susan L Cusack"

The pharmacokinetics and safety of an intraoperative bupivacaine-collagen implant (XaraColl®) for postoperative analgesia in women following total abdominal hysterectomy

Autor: Lisa Hemsen, Susan L Cusack, Philip Reginald, Emmanuel Umerah

Publikováno v: Journal of Pain Research

Susan L Cusack,1 Philip Reginald,2 Lisa Hemsen,3 Emmanuel Umerah21Cusack Pharmaceutical Consulting, Burlington, NJ, USA; 2Departments of Gynaecology and Anaesthetics, Wexham Park Hospital, Slough, SL2 4HL, UK; 3Innocoll Technologies, Athlone, Ireland

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895f9737ba652fff9377373079e950ab
http://europepmc.org/articles/PMC3594918

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A Phase I Study of ABC294640, a First-in-Class Sphingosine Kinase-2 Inhibitor, in Patients with Advanced Solid Tumors

Autor: Tricia A. Bentz, Susan L. Cusack, Charles D. Smith, Keisuke Shirai, Yan Zhuang, Kate Anderton, Carolyn D. Britten, Steven H. Chin, Besim Ogretmen, Elizabeth Garrett-Mayer, Melanie B. Thomas, Alan Brisendine, Lynn W. Maines

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 23(16)

Purpose: Sphingosine kinases (SK1 and SK2) regulate tumor growth by generating the mitogenic and proinflammatory lipid sphingosine 1-phosphate (S1P). This phase I study investigated the safety, pharmacokinetics, pharmacodynamics, and antitumor activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16533c2d5bc89970115840570d927d45
https://pubmed.ncbi.nlm.nih.gov/28420720

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A feasibility study to investigate the use of a bupivacaine-collagen implant (XaraColl) for postoperative analgesia following laparoscopic surgery

Autor: Michael Kuss, Lisa Hemsen, Susan L Cusack, Harold S. Minkowitz

Publikováno v: Journal of Pain Research

Lisa Hemsen,1 Susan L Cusack,2 Harold S Minkowitz,3 Michael E Kuss41Innocoll Technologies, Athlone, Ireland; 2Cusack Pharmaceutical Consulting, Burlington, NJ, USA; 3Memorial Hermann Memorial City Medical Center, Houston, TX, USA; 4Premier Research G

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736f8e7587c82608e6529347e8fe8a2a
https://pubmed.ncbi.nlm.nih.gov/23390367

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Abstract C62: Phase I trial of ABC294640, a first-in-class sphingosine kinase-2 inhibitor

Autor: Yan Zhuang, Terri Matson, Susan L. Cusack, Charles D. Smith, Carolyn D. Britten, Elizabeth Garrett-Mayer, Steve H. Chin, Lynn W. Maines, Melanie B. Thomas, Alan Brisendine, Tricia A. Bentz

Publikováno v: Molecular Cancer Therapeutics. 12:C62-C62

Sphingosine kinases (SK1 and SK2) are new potential targets for anticancer drugs because SK inhibitors elevate ceramide levels thereby promoting apoptosis of tumor cells, and concomitantly reduce sphingosine 1-phosphate (S1P) levels thereby attenuati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efa9aefa0480a1a7e79662e6613594c4
https://doi.org/10.1158/1535-7163.targ-13-c62

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A randomized, multicenter, pilot study comparing the efficacy and safety of a bupivacaine-collagen implant (XaraColl®) with the ON-Q PainBuster® Post-op Pain Relief System following open gynecological surgery

Autor: Susan L Cusack, Lisa Hemsen, Mark Jaros, Harold S. Minkowitz, Michael Kuss

Publikováno v: Journal of Pain Research

Susan L Cusack,1 Harold S Minkowitz,2 Michael Kuss,3 Mark Jaros,4 Lisa Hemsen51Cusack Pharmaceutical Consulting, Burlington, NJ, 2Memorial Hermann Memorial City Medical Center, Houston, TX, USA; 3Premier Research Group, Austin, TX, USA; 4Summit Analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10dc2b516f2a376f25a8b01c7a0d39cd
https://doi.org/10.2147/jpr.s37310

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