Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan L Campbell"'
Autor:
Fumiaki Yokoi, Huan-Xin Chen, Mai Tu Dang, Chad C Cheetham, Susan L Campbell, Steven N Roper, J David Sweatt, Yuqing Li
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120916 (2015)
DYT1 dystonia is an inherited movement disorder caused by mutations in DYT1 (TOR1A), which codes for torsinA. Most of the patients have a trinucleotide deletion (ΔGAG) corresponding to a glutamic acid in the C-terminal region (torsinA(ΔE)). Dyt1 Δ
Externí odkaz:
https://doaj.org/article/f358a7afcaec458fbca1b68aab27d38b
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Cortical dysplasia is associated with intractable epilepsy and developmental delay in young children. Recent work with the rat freeze-induced focal cortical dysplasia (FCD) model has demonstrated that hyperexcitability in the dysplastic cortex is due
Externí odkaz:
https://doaj.org/article/4c08c308676d43d2ab09609a2c6ef177
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72491 (2013)
DYT1 early-onset generalized torsion dystonia (DYT1 dystonia) is an inherited movement disorder caused by mutations in one allele of DYT1 (TOR1A), coding for torsinA. The most common mutation is a trinucleotide deletion (ΔGAG), which causes a deleti
Externí odkaz:
https://doaj.org/article/e45a2504d9154a959076024f5bb1eaa1
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThere is a growing interest in the role of the gut microbiota in epilepsy, however, it is unclear if anti-seizure medications (ASMs) play a role in the gut-brain axis. To test this, we investigated the impact of the ASM topiramate on the
Externí odkaz:
https://doaj.org/article/fd1bfd5db9ae4b28bd3137fbd2f50352
Autor:
Jianping Wu, Meng Jia, Qian Zhang, Xi Guo, Ru Liu, Sha Liu, Nanyu Chen, Yunfu Wang, Qun Wang, Susan L. Campbell
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 22:1109-1119
Background: Metabolic acidosis plays a key role in transient global cerebral ischemiareperfusion (I/R) induced delayed neuronal death (DND) of the hippocampal CA1 region of gerbils. Na+ coupled HCO3 - transporters (NBCs) mediated Na+/HCO3 - co-transp
Publikováno v:
Epilepsia. 63:844-854
Objective Previously, we reported that inhibition of the astrocytic cystine/glutamate antiporter system xc- (SXC), using sulfasalazine (SAS), decreased evoked excitatory signaling in three distinct hyperexcitability models ex vivo. The current study
Autor:
Elsie C. Spencer, Kit Neikirk, Susan L. Campbell, Keesha L. Powell-Roach, Derrick Morton, Haysetta Shuler, Sandra A. Murray, Antentor Hinton
Publikováno v:
Trends Microbiol
A faculty position can be a balancing act. Many new faculty, particularly minorities, struggle due to a lack of mentorship. Writing accountability groups (WAGs) offer new faculty an opportunity to glean advice from mentors and improve their writing s
Autor:
Huiting, Xia, Aqeela, Zahra, Meng, Jia, Qun, Wang, Yunfu, Wang, Susan L, Campbell, Jianping, Wu
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(7)
Cardiac hypertrophy is defined as increased heart mass in response to increased hemodynamic requirements. Long-term cardiac hypertrophy, if not counteracted, will ultimately lead to heart failure. The incidence of heart failure is related to myocardi
Autor:
Jianping Wu, Aqeela Zahra, Ru Liu, Wenzhe Han, Hui Meng, Qun Wang, YunFu Wang, Susan L. Campbell
Publikováno v:
Current neuropharmacology.
Abstract: Although potassium channelopathies have been linked to a wide range of neurological con- ditions, the underlying pathogenic mechanism is not always clear, and a systematic summary of clini- cal manifestation is absent. Several neurological
Publikováno v:
Pharmaceuticals. 15:875
Cardiac hypertrophy is defined as increased heart mass in response to increased hemodynamic requirements. Long-term cardiac hypertrophy, if not counteracted, will ultimately lead to heart failure. The incidence of heart failure is related to myocardi