Výsledky vyhledávání - "Susan L Bellis"

Akademický článek

Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase.

Autor: Andrew T Holdbrooks, Katherine E Ankenbauer, Jihye Hwang, Susan L Bellis

Publikováno v: PLoS ONE, Vol 15, Iss 11, p e0241850 (2020)

The ST6Gal-I sialyltransferase, an enzyme that adds α2-6-linked sialic acids to N-glycosylated proteins, regulates multiple immunological processes. However, the contribution of receptor sialylation to inflammatory signaling has been under-investiga

Externí odkaz: https://doaj.org/article/8c5bddeff390480cb8fe5b3b89f7ddfd

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Akademický článek

The addition of a polyglutamate domain to the angiogenic QK peptide improves peptide coupling to bone graft materials leading to enhanced endothelial cell activation.

Autor: Nicholas W Pensa, Andrew S Curry, Michael S Reddy, Susan L Bellis

Publikováno v: PLoS ONE, Vol 14, Iss 3, p e0213592 (2019)

Vascularization of bone grafts is vital for graft integration and bone repair, however non-autologous graft sources have limited potential to induce angiogenesis. Accordingly, intensive research has focused on functionalizing non-autologous materials

Externí odkaz: https://doaj.org/article/e8aaae5f70f84692a3447b3f8bc6da72

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Akademický článek

Addition of an oligoglutamate domain to bone morphogenic protein 2 confers binding to hydroxyapatite materials and induces osteoblastic signaling.

Autor: Andrew S Curry, David T McPherson, Abby M Barlow, Nicholas W Pensa, Michael S Reddy, Susan L Bellis

Publikováno v: PLoS ONE, Vol 14, Iss 5, p e0217766 (2019)

Nonautologous bone grafts have limited osteoinductive potential and thus there is substantial interest in reconstituting these graft materials with osteogenic factors such as bone morphogenic protein 2 (BMP2). However, one limitation of this approach

Externí odkaz: https://doaj.org/article/0bc69c8501904a03bc7daca0b369383b

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Akademický článek

Microporous dermal-mimetic electrospun scaffolds pre-seeded with fibroblasts promote tissue regeneration in full-thickness skin wounds.

Autor: Paul P Bonvallet, Matthew J Schultz, Elizabeth H Mitchell, Jennifer L Bain, Bonnie K Culpepper, Steven J Thomas, Susan L Bellis

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0122359 (2015)

Electrospun scaffolds serve as promising substrates for tissue repair due to their nanofibrous architecture and amenability to tailoring of chemical composition. In this study, the regenerative potential of a microporous electrospun scaffold pre-seed

Externí odkaz: https://doaj.org/article/062518178acb4348b2123e357cd3fdbd

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Akademický článek

Delivery of platelet-derived growth factor as a chemotactic factor for mesenchymal stem cells by bone-mimetic electrospun scaffolds.

Autor: Matthew C Phipps, Yuanyuan Xu, Susan L Bellis

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e40831 (2012)

The recruitment of mesenchymal stem cells (MSCs) is a vital step in the bone healing process, and hence the functionalization of osteogenic biomaterials with chemotactic factors constitutes an important effort in the tissue engineering field. Previou

Externí odkaz: https://doaj.org/article/b23cca0e6ebc4fb296592576a51ae5df

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Akademický článek

Mesenchymal stem cell responses to bone-mimetic electrospun matrices composed of polycaprolactone, collagen I and nanoparticulate hydroxyapatite.

Autor: Matthew C Phipps, William C Clem, Shane A Catledge, Yuanyuan Xu, Kristin M Hennessy, Vinoy Thomas, Michael J Jablonsky, Shafiul Chowdhury, Andrei V Stanishevsky, Yogesh K Vohra, Susan L Bellis

Publikováno v: PLoS ONE, Vol 6, Iss 2, p e16813 (2011)

The performance of biomaterials designed for bone repair depends, in part, on the ability of the material to support the adhesion and survival of mesenchymal stem cells (MSCs). In this study, a nanofibrous bone-mimicking scaffold was electrospun from

Externí odkaz: https://doaj.org/article/94e3fd863d22444784ca43d8b11a0b7e

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Akademický článek

ST6GAL1 is associated with poor response to chemoradiation in rectal cancer

Autor: Mary Smithson, Sameer Al Diffalha, Regina K. Irwin, Gregory Williams, M. Chandler McLeod, Vivek Somasundaram, Susan L. Bellis, Karin M. Hardiman

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 51, Iss , Pp 100984- (2024)

Introduction: Colorectal cancer is the third most common cause of cancer death. Rectal cancer makes up a third of all colorectal cases. Treatment for locally advanced rectal cancer includes chemoradiation followed by surgery. We have previously ident

Externí odkaz: https://doaj.org/article/1269f983907643b48b84dec6e131a9ab

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