Zobrazeno 1 - 10
of 344
pro vyhledávání: '"Susan L, Cohn"'
Autor:
Monica Pomaville, Mohansrinivas Chennakesavalu, Pingluan Wang, Zhiwei Jiang, Hui-Lung Sun, Peizhe Ren, Ryan Borchert, Varsha Gupta, Chang Ye, Ruiqi Ge, Zhongyu Zhu, Mallory Brodnik, Yuhao Zhong, Kelley Moore, Helen Salwen, Rani E. George, Malgorzata Krajewska, Alexandre Chlenski, Mark A. Applebaum, Chuan He, Susan L. Cohn
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114165- (2024)
Summary: The N6-methyladenosine (m6A) RNA modification is an important regulator of gene expression. m6A is deposited by a methyltransferase complex that includes methyltransferase-like 3 (METTL3) and methyltransferase-like 14 (METTL14). High levels
Externí odkaz:
https://doaj.org/article/b70135c60c274c8db78ac7b2b49f0621
Autor:
Mohansrinivas Chennakesavalu, Caileigh Pudela, Mark A. Applebaum, Sang Mee Lee, Yan Che, Arlene Naranjo, Julie R. Park, Samuel L. Volchenboum, Tara O. Henderson, Susan L. Cohn, Ami V. Desai
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100022- (2023)
Background: Racial/ethnic survival disparities in neuroblastoma were first reported more than a decade ago. We sought to investigate if these disparities have persisted with current era therapy. Methods: Two patient cohorts were identified in the Int
Externí odkaz:
https://doaj.org/article/0884887593ac4022bd8dab8a00e8d3e1
Autor:
Anastasia E. Hains, Sakshi Uppal, John Z. Cao, Helen R. Salwen, Mark A. Applebaum, Susan L. Cohn, Lucy A. Godley
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2056-2074 (2022)
Ten-Eleven-Translocation 5-methylcytosine dioxygenases 1–3 (TET1-3) convert 5-methylcytosine to 5-hydroxymethylcytosine (5-hmC), using oxygen as a co-substrate. Contrary to expectations, hypoxia induces 5-hmC gains in MYCN-amplified neuroblastoma (
Externí odkaz:
https://doaj.org/article/46684909df9349bab0c0b5b0bbd13c9a
Autor:
Ami V. Desai, Andrew L. Gilman, Mehmet Fevzi Ozkaynak, Arlene Naranjo, Wendy B. London, Sheena C. Tenney, Mitchell Diccianni, Jacquelyn A. Hank, Marguerite T. Parisi, Barry L. Shulkin, Malcolm Smith, Jeffrey A. Moscow, Hiroyuki Shimada, Katherine K. Matthay, Susan L. Cohn, John M. Maris, Rochelle Bagatell, Paul M. Sondel, Julie R. Park, Alice L. Yu
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(35)
PURPOSEPostconsolidation immunotherapy including dinutuximab, granulocyte-macrophage colony-stimulating factor, and interleukin-2 improved outcomes for patients with high-risk neuroblastoma enrolled on the randomized portion of Children's Oncology Gr
Autor:
Ami V Desai, Stefani Spranger, Thomas F Gajewski, Yuanyuan Zha, Riyue Bao, Jason J Luke, Peter Pytel, Kyle Hernandez, Samuel L Volchenboum, Susan L Cohn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Tumor-infiltrating CD8+ T cells and neoantigens are predictors of a favorable prognosis and response to immunotherapy with checkpoint inhibitors in many types of adult cancer, but little is known about their role in pediatric malignancies.
Externí odkaz:
https://doaj.org/article/b260b4d6e43c4d658b87dc58bb5c263c
Autor:
Danielle Novetsky Friedman, Pamela J. Goodman, Wendy M. Leisenring, Lisa R. Diller, Susan L. Cohn, Rebecca M. Howell, Susan A. Smith, Emily S. Tonorezos, Suzanne L. Wolden, Joseph P. Neglia, Kirsten K. Ness, Todd M. Gibson, Paul C. Nathan, Brent R. Weil, Leslie L. Robison, Kevin C. Oeffinger, Gregory T. Armstrong, Charles A. Sklar, Tara O. Henderson
Publikováno v:
Journal of Clinical Oncology. 41:1565-1576
PURPOSE To describe the risk of late mortality, subsequent malignant neoplasms (SMNs), and chronic health conditions (CHCs) in survivors of neuroblastoma diagnosed in infancy by treatment era and exposures. METHODS Among 5-year survivors of neuroblas
Autor:
Anastasia E, Hains, Sakshi, Uppal, John Z, Cao, Helen R, Salwen, Mark A, Applebaum, Susan L, Cohn, Lucy A, Godley
Publikováno v:
Epigenetics. 17(13)
Ten-Eleven-Translocation 5-methylcytosine dioxygenases 1-3 (TET1-3) convert 5-methylcytosine to 5-hydroxymethylcytosine (5-hmC), using oxygen as a co-substrate. Contrary to expectations, hypoxia induces 5-hmC gains inIn
Autor:
Ami V. Desai, Mark A. Applebaum, Theodore G. Karrison, Akosua Oppong, Cindy Yuan, Katherine R. Berg, Kyle MacQuarrie, Elizabeth Sokol, Anurekha G. Hall, Navin Pinto, Ian Wolfe, Rajen Mody, Suzanne Shusterman, Valeria Smith, Jennifer H. Foster, Michele Nassin, James L. LaBelle, Rochelle Bagatell, Susan L. Cohn
Publikováno v:
Cancer. 128:2967-2977
High-risk neuroblastoma patients with end-induction residual disease commonly receive post-induction therapy in an effort to increase survival by improving the response before autologous stem cell transplantation (ASCT). The authors conducted a multi
Autor:
Hannah G. Bender, Meredith S. Irwin, Michael D. Hogarty, Robert Castleberry, John M. Maris, Pei-Chi Kao, Fan F. Zhang, Arlene Naranjo, Susan L. Cohn, Wendy B. London
Publikováno v:
Journal of Clinical Oncology.
PURPOSE In 2006, Children's Oncology Group (COG) reclassified subgroups of toddlers diagnosed with neuroblastoma from high-risk to intermediate-risk, when the age cutoff for high-risk assignment was raised from 365 days (12 months) to 547 days (18 mo
Autor:
Susan L. Cohn, Philip P. Connell, Yusuke Nakamura, Emma Wilkinson, Mark A. Applebaum, Ryan Miller, Jae-Hyun Park, Brian Budke, Helen R. Salwen, Marija Dobratic, Chanyoung Park, Alexandre Chlenski
MYCN/MYC expression in N-type and S-type neuroblastoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03019b2e4e013bb650ca3b7c2f1f466a
https://doi.org/10.1158/1535-7163.22507038.v1
https://doi.org/10.1158/1535-7163.22507038.v1