Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan L, Campbell"'
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionThere is a growing interest in the role of the gut microbiota in epilepsy, however, it is unclear if anti-seizure medications (ASMs) play a role in the gut-brain axis. To test this, we investigated the impact of the ASM topiramate on the
Externí odkaz:
https://doaj.org/article/fd1bfd5db9ae4b28bd3137fbd2f50352
Autor:
Jianping Wu, Meng Jia, Qian Zhang, Xi Guo, Ru Liu, Sha Liu, Nanyu Chen, Yunfu Wang, Qun Wang, Susan L. Campbell
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 22:1109-1119
Background: Metabolic acidosis plays a key role in transient global cerebral ischemiareperfusion (I/R) induced delayed neuronal death (DND) of the hippocampal CA1 region of gerbils. Na+ coupled HCO3 - transporters (NBCs) mediated Na+/HCO3 - co-transp
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 875 (2022)
Cardiac hypertrophy is defined as increased heart mass in response to increased hemodynamic requirements. Long-term cardiac hypertrophy, if not counteracted, will ultimately lead to heart failure. The incidence of heart failure is related to myocardi
Externí odkaz:
https://doaj.org/article/d1375ba8f5a6433abda5591f9b369907
Autor:
Lata Chaunsali, Bhanu P. Tewari, Allison Gallucci, Emily G. Thompson, Andrew Savoia, Noah Feld, Susan L. Campbell
Publikováno v:
Physiological Reports, Vol 8, Iss 19, Pp n/a-n/a (2020)
Abstract Epileptic seizures are among the most common presenting symptom in patients with glioma. The etiology of glioma‐related seizures is complex and not completely understood. Studies using adult glioma patient tissue and adult glioma mouse mod
Externí odkaz:
https://doaj.org/article/4edf9e53bfe2482ba07c96b391a35d23
Autor:
Bhanu P. Tewari, Lata Chaunsali, Susan L. Campbell, Dipan C. Patel, Adam E. Goode, Harald Sontheimer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Brain tumours are associated with epilepsy. Here the authors show, using a mouse model, that the degradation of perineuronal nets around fast spiking interneurons near the tumour contribute to seizures by increasing their membrane capacitance and fir
Externí odkaz:
https://doaj.org/article/76ee429c0d5743bdbdf32e9dfbd740e1
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-20 (2017)
Abstract Background PDE4 cyclic nucleotide phosphodiesterases regulate 3′, 5′ cAMP abundance in the CNS and thereby regulate PKA activity and phosphorylation of CREB, which has been implicated in learning and memory, depression and other function
Externí odkaz:
https://doaj.org/article/cc4c65e396c04c169a96cf0d02d4e567
Publikováno v:
Epilepsia. 63:844-854
Objective Previously, we reported that inhibition of the astrocytic cystine/glutamate antiporter system xc- (SXC), using sulfasalazine (SAS), decreased evoked excitatory signaling in three distinct hyperexcitability models ex vivo. The current study
Autor:
Elsie C. Spencer, Kit Neikirk, Susan L. Campbell, Keesha L. Powell-Roach, Derrick Morton, Haysetta Shuler, Sandra A. Murray, Antentor Hinton
Publikováno v:
Trends Microbiol
A faculty position can be a balancing act. Many new faculty, particularly minorities, struggle due to a lack of mentorship. Writing accountability groups (WAGs) offer new faculty an opportunity to glean advice from mentors and improve their writing s
Autor:
Huiting, Xia, Aqeela, Zahra, Meng, Jia, Qun, Wang, Yunfu, Wang, Susan L, Campbell, Jianping, Wu
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(7)
Cardiac hypertrophy is defined as increased heart mass in response to increased hemodynamic requirements. Long-term cardiac hypertrophy, if not counteracted, will ultimately lead to heart failure. The incidence of heart failure is related to myocardi
Autor:
Jianping Wu, Aqeela Zahra, Ru Liu, Wenzhe Han, Hui Meng, Qun Wang, YunFu Wang, Susan L. Campbell
Publikováno v:
Current neuropharmacology.
Abstract: Although potassium channelopathies have been linked to a wide range of neurological con- ditions, the underlying pathogenic mechanism is not always clear, and a systematic summary of clini- cal manifestation is absent. Several neurological