Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Susan Klinedinst"'
Autor:
Jiaxing Li, Yao V Zhang, Elham Asghari Adib, Doychin T Stanchev, Xin Xiong, Susan Klinedinst, Pushpanjali Soppina, Thomas Robert Jahn, Richard I Hume, Tobias M Rasse, Catherine A Collins
Publikováno v:
eLife, Vol 6 (2017)
The kinesin-3 family member Unc-104/KIF1A is required for axonal transport of many presynaptic components to synapses, and mutation of this gene results in synaptic dysfunction in mice, flies and worms. Our studies at the Drosophila neuromuscular jun
Externí odkaz:
https://doaj.org/article/79619f4a1fa4450f97a7863533408fc2
Autor:
Matthias Siebert, Mathias A Böhme, Jan H Driller, Husam Babikir, Malou M Mampell, Ulises Rey, Niraja Ramesh, Tanja Matkovic, Nicole Holton, Suneel Reddy-Alla, Fabian Göttfert, Dirk Kamin, Christine Quentin, Susan Klinedinst, Till FM Andlauer, Stefan W Hell, Catherine A Collins, Markus C Wahl, Bernhard Loll, Stephan J Sigrist
Publikováno v:
eLife, Vol 4 (2015)
Synaptic vesicles (SVs) fuse at active zones (AZs) covered by a protein scaffold, at Drosophila synapses comprised of ELKS family member Bruchpilot (BRP) and RIM-binding protein (RBP). We here demonstrate axonal co-transport of BRP and RBP using intr
Externí odkaz:
https://doaj.org/article/cc5f709ea3a149bb840b71b1ba400d10
Autor:
Doychin T. Stanchev, Jiaxing Li, Pushpanjali Soppina, Susan Klinedinst, Richard I. Hume, Yao V. Zhang, Tobias M. Rasse, Catherine A. Collins, Elham Asghari Adib, Xin Xiong, Thomas R. Jahn
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The kinesin-3 family member Unc-104/KIF1A is required for axonal transport of many presynaptic components to synapses, and mutation of this gene results in synaptic dysfunction in mice, flies and worms. Our studies at the Drosophila neuromuscular jun
Autor:
Pushpanjali Soppina, Catherine A. Collins, Susan Klinedinst, Yao V. Zhang, Elham Asghari Adib, Tobias M. Rasse, Jiaxing Li, Thomas R. Jahn, Doychin T. Stanchev, Xin Xiong, Richard I. Hume
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::449983e8bde97e1e689bddcbfe69782a
https://doi.org/10.7554/elife.24271.032
https://doi.org/10.7554/elife.24271.032
Publikováno v:
Journal of Neuroscience. 33:12764-12778
Mitogen-activated protein (MAP) kinase signaling cascades orchestrate diverse cellular activities with common molecular players. To achieve specific cellular outcomes in response to specific signals, scaffolding proteins play an important role. Here
Autor:
William B. Pratt, Yoichi Osawa, Andrew P. Lieberman, Jason E. Gestwicki, Catherine A. Collins, Jason P. Chua, Xiaokai Li, Hwei Ming Peng, Adrienne M. Wang, Diane E. Merry, Susan Klinedinst, Tomoko Komiyama, Yoshinari Miyata, Yoshihiro Morishima
Publikováno v:
Nature chemical biology
We sought new strategies to reduce amounts of the polyglutamine androgen receptor (polyQ AR) and achieve benefits in models of spinobulbar muscular atrophy, a protein aggregation neurodegenerative disorder. Proteostasis of the polyQ AR is controlled
Publikováno v:
Plant Molecular Biology. 42:679-688
In plants, as-1-type cis elements and their trans-acting factors confer tissue-specific and signal-responsive activities to the promoters of several glutathione S-transferase (GST) genes. Regulation of as-1 is widely thought to involve trans-acting f
Autor:
Erika L. Bustamante, Seung K. Kim, Karen Ocorr, Susan Klinedinst, Rolf Bodmer, Takeshi Akasaka
The homeobox transcription factor Tinman plays an important role in the initiation of heart development. Later functions of Tinman, including the target genes involved in cardiac physiology, are less well studied. We focused on the dSUR gene, which e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0cc103047850103935882d4340079e
https://europepmc.org/articles/PMC1567687/
https://europepmc.org/articles/PMC1567687/
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 235(8)
The Drosophila how gene encodes a KH RNA binding protein with strong similarity to GLD-1 from nematodes and QK1 from mice. Here, we investigate the function of how during metamorphosis. We show that how RNA and protein are present in a variety of tis
Autor:
Rolf Bodmer, Susan Klinedinst
Publikováno v:
Development (Cambridge, England). 130(13)
Inductive signaling is of pivotal importance for developmental patterns to form. In Drosophila, the transfer of TGFβ (Dpp) and Wnt (Wg)signaling information from the ectoderm to the underlying mesoderm induces cardiac-specific differentiation in the