Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Susan Kimber"'
Publikováno v:
Bio-Protocol, Vol 11, Iss 17 (2021)
MicroRNAs are small RNAs that negatively regulate gene expression and play an important role in fine-tuning molecular pathways during development. There is increasing interest in studying their function in the kidney, but the majority of studies to d
Externí odkaz:
https://doaj.org/article/2be87c14d7d24043a04a1602799960c8
Autor:
Stuart Cain, Paul Humphreys, Mark Naven, Christopher Andrew Smith, Mona Dvir-Ginzberg, Susan Kimber, Nicola Bates
Publikováno v:
Smith, C A, Humphreys, P A, Bates, N, Naven, M A, Cain, S A, Dvir-Ginzberg, M & Kimber, S J 2022, ' SIRT1 activity orchestrates ECM expression during hESC-chondrogenic differentiation ', FASEB Journal, vol. 36, no. 5, e22314 . https://doi.org/10.1096/fj.202200169R
Epigenetic modification is a key driver of differentiation, and the deacetylase Sirtuin1 (SIRT1) is an established regulator of cell function, ageing, and articular cartilage homeostasis. Here we investigate the role of SIRT1 during development of ch
Autor:
Mychel Raony Paiva Teixeira Morais, Pinyuan Tian, Craig Lawless, Syed Murtuza-Baker, Louise Hopkinson, Steven Woods, Aleksandr Mironov, David Andrew Long, Daniel Gale, Telma Maria Tenorio Zorn, Susan Kimber, Roy Zent, Rachel Lennon
SUMMARYBasement membranes (BMs) are complex macromolecular networks underlying all continuous layers of cells. Essential components include type IV collagen and laminins, which are affected by human genetic defects leading to a range of debilitating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3d06ec35cf7e22fb0d3d3f5d729ed88
https://doi.org/10.1101/2021.06.27.450067
https://doi.org/10.1101/2021.06.27.450067
Publikováno v:
Europe PubMed Central
Eggs of the marine gastropod Crepidula fornicata examined by confocal imaging of FITC-lectin binding to the surface, and cryoscopic-SEM both reveal a surface architecture of linear structures organized around the animal-vegetal axis, which is spatial
Publikováno v:
Europe PubMed Central
The cell surface glycoprotein CD44 has been demonstrated in a variety of cell types in embryonic and adult tissues. We have established that CD44 is present on human oocytes, cumulus cells, early embryos and pre-hatched blastocysts by indirect immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a90dc14c8fe1573dcc170b21c42833c4
http://europepmc.org/abstract/med/7539449
http://europepmc.org/abstract/med/7539449
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
The expression of the cell adhesion molecule of the immunoglobulin family, neural cell adhesion molecule (N-CAM), in the pre- and periimplantation embryo was examined by immunocytochemistry. N-CAM is expressed on unfertilized ovulated oocytes, fertil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::473c7c4ed602403614d2a0e8d8a1a17a
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028345012&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0028345012&partnerID=MN8TOARS
Publikováno v:
University of Manchester-PURE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::18e3006d3fb8eff17de74ddc30158ec1
https://research.manchester.ac.uk/en/publications/d5c2b89b-2f09-45c7-a7f6-15c2b93fe69d
https://research.manchester.ac.uk/en/publications/d5c2b89b-2f09-45c7-a7f6-15c2b93fe69d
Publikováno v:
Europe PubMed Central
Hydroxymethyl glutaryl Co A reductase (HMG Co A reductase) is the key regulatory enzyme in the conversion of acetate to mevalonate. Mevalonate is the precursor for sterol and non-sterol isoprenes involved in membrane biogenesis, DNA replication and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0368c8d47cf990a85f56521eb972a27f
http://europepmc.org/abstract/med/6886611
http://europepmc.org/abstract/med/6886611
Publikováno v:
Europe PubMed Central
During development of the mammalian tooth germ the pattern of terminal saccharides of glycoconjugates changes, with many structures losing lectin reactivity in a consistent pattern. This study investigated whether the epitopes are lost or become mask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4257606f76faa3546bca88c12604fb10
http://europepmc.org/abstract/med/7559118
http://europepmc.org/abstract/med/7559118