Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Susan K. Morton"'
Autor:
Corey S. Moran, Erik Biros, Smriti M. Krishna, Susan K. Morton, Daniel J. Sexton, Jonathan Golledge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. The kinin B2 receptor agonist, bradykinin, has been implicated in AAA pathogenesis through promoting inflammation. Bradykinin is generated from high‐ and
Externí odkaz:
https://doaj.org/article/500c9d85cf9542239494ac2dc7411197
Autor:
Sophie E. Rowbotham, Jenna L. Pinchbeck, Georgina Anderson, Bernie Bourke, Michael Bourke, T. Christian Gasser, Rene Jaeggi, Jason S. Jenkins, Corey S. Moran, Susan K. Morton, Christopher M. Reid, Ramesh Velu, Lisan Yip, Joseph V. Moxon, Jonathan Golledge
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background An abdominal aortic aneurysm (AAA) is a focal dilation of the abdominal aorta and is associated with a risk of fatal rupture. Experimental studies suggest that myo-inositol may exert beneficial effects on AAAs through favourable c
Externí odkaz:
https://doaj.org/article/729c7f8d1edf43549b747094e3d31d45
Autor:
Jenna L. Pinchbeck, Joseph V. Moxon, Sophie E. Rowbotham, Michael Bourke, Sharon Lazzaroni, Susan K. Morton, Evan O. Matthews, Kerolos Hendy, Rhondda E. Jones, Bernie Bourke, Rene Jaeggi, Danella Favot, Frank Quigley, Jason S. Jenkins, Christopher M. Reid, Ramesh Velu, Jonathan Golledge
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 19 (2018)
Background There is no drug therapy for abdominal aortic aneurysm (AAA). FAME‐2 (Fenofibrate in the Management of Abdominal Aortic Aneurysm 2) was a placebo‐controlled randomized trial designed to assess whether administration of 145 mg of fenofi
Externí odkaz:
https://doaj.org/article/d10f5da433004a3bacc6e93f9578f888
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7250 (2020)
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in older adults. In clinical practice, the most established predictor of AAA rupture is maximum AAA diameter. Aortic diameter is commonly used to assess AAA severity in mouse mode
Externí odkaz:
https://doaj.org/article/6a8020a126174d848cb0d797870d335b
Autor:
Susan K Morton, Alexander J Rodríguez, Dylan R Morris, Abhishta P Bhandari, Joseph V Moxon, Jonathan Golledge
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159963 (2016)
Arteriovenous fistula (AVF) failure is a significant cause of morbidity and expense in patients on maintenance haemodialysis (HD). Circulating biomarkers could be valuable in detecting patients at risk of AVF failure and may identify targets to impro
Externí odkaz:
https://doaj.org/article/1291979eeb79414082e0be1a58a0ab36
Autor:
Jason Jenkins, Doug Cavaye, Susan K. Morton, Frank Quigley, Jenna Pinchbeck, Joseph V. Moxon, Jonathan Golledge, Sophie E. Rowbotham, Rene Jaeggi, Corey S. Moran, Sharon Lazzaroni, Christopher M. Reid
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 60:452-460
Objective Experimental studies suggest that fenofibrate prevents abdominal aortic aneurysm (AAA) development by lowering aortic osteopontin (OPN) concentration and reducing the number of macrophages infiltrating the aortic wall. The current study exa
Autor:
Susan K. Morton, Corey S. Moran, Jonathan Golledge, Smriti M. Krishna, Joseph V. Moxon, Vianne Nsengiyumva, Michael W. Clarke, Sai Wang Seto
Publikováno v:
Clinical Science (London, England : 1979)
Vitamin D deficiency has been associated with human abdominal aortic aneurysm (AAA); however, its role in AAA pathogenesis is unclear. The aim of the present study was to investigate the effect of vitamin D deficiency on AAA development and examine i
Autor:
Jiaze Li, Smriti M. Krishna, Roby J. Jose, Jonathan Golledge, Safraz Mohamed Omer, Susan K. Morton
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Peripheral arterial disease (PAD) develops due to the narrowing or blockage of arteries supplying blood to the lower limbs. Surgical and endovascular interventions are the main treatments for advanced PAD but alternative and adjunctive medical therap
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95980 (2014)
Genetically modified mice have played an important part in elucidating gene function in vivo. However, conclusions from transgenic studies may be compromised by complications arising from the site of transgene integration into the genome and, in indu
Externí odkaz:
https://doaj.org/article/5de9012ae57841ffbbc45a6fe6cdb646
Autor:
Jonathan Golledge, Smriti M. Krishna, Susan K. Morton, Daniel J. Sexton, Corey S. Moran, Erik Biros
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
BackgroundAbdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. The kinin B2 receptor agonist, bradykinin, has been implicated in AAA pathogenesis through promoting inflammation. Bradykinin is generated from high‐ and