Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Susan K Peirce"'
Autor:
Adriana Papadimitropoulou, Sara Verdura, Ruth Lupu, Luciano Vellon, Javier A. Menendez, Travis Vander Steen, Elisabet Cuyàs, Wen Y. Chen, Susan K Peirce
Publikováno v:
Aging, 2020, vol. 12, núm. 24, p. 24671-24692
Articles publicats (IdIBGi)
Menéndez Menéndez, Javier Abel Peirce, Susan K. Papadimitropoulou, Adriana Cuyàs, Elisabet Van der Steen, Travis Verdura, Sara Vellon, Luciano Chen, Wen Y. Lupu, Ruth 2020 Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer Aging 12 24 24671 24692
DUGiDocs – Universitat de Girona
instname
Aging (Albany NY)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Articles publicats (IdIBGi)
Menéndez Menéndez, Javier Abel Peirce, Susan K. Papadimitropoulou, Adriana Cuyàs, Elisabet Van der Steen, Travis Verdura, Sara Vellon, Luciano Chen, Wen Y. Lupu, Ruth 2020 Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer Aging 12 24 24671 24692
DUGiDocs – Universitat de Girona
instname
Aging (Albany NY)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Progesterone receptor (PR) isoforms can drive unique phenotypes in luminal breast cancer (BC). Here, we hypothesized that PR-B and PR-A isoforms differentially modify the cross-talk between prolactin and fatty acid synthase (FASN) in BC. We profiled
Autor:
Susan K. Peirce, Annette Vu, Dema Luyindula, Michelle Gross, Huaqing Zhao, Kelly C. Goldsmith, Michael D. Hogarty, Michael Sliozberg, Xueyuan Liu, Rong Guo, C. Patrick Reynolds
Publikováno v:
Cancer Research. 72:2565-2577
Neuroblastoma is a childhood tumor in which transient therapeutic responses are typically followed by recurrence with lethal chemoresistant disease. In this study, we characterized the apoptotic responses in diverse neuroblastomas using an unbiased m
Autor:
Susan K. Peirce, Luciano Vellon, Barbara Schroeder, Ingrid Espinoza, Javier A. Menendez, Ruth Lupu, Adriana Papadimitropoulou
Publikováno v:
JNCI: Journal of the National Cancer Institute. 107
Background: Several treatment strategies target the human epidermal growth factor receptor 2 (HER2) in breast carcinomas, including monoclonal antibodies directed against HER2?s extracellular domain (ECD) and small molecule inhibitors of its tyrosine
Autor:
Michael D. Hogarty, Kelly C. Goldsmith, Dipan Karmali, Susan K. Peirce, Srilatha Nalluri, Haneen Abdella, Rachel Tanos
Publikováno v:
Cancer biologytherapy. 16(2)
The pediatric solid tumor neuroblastoma (NB) often depends on the anti-apoptotic protein, Mcl(-)1, for survival through Mcl(-)1 sequestration of pro-apoptotic Bim. High affinity Mcl(-)1 inhibitors currently do not exist such that novel methods to inh
Autor:
Wen Y. Chen, Susan K Peirce
Publikováno v:
Oncogene. 23:1248-1255
To gain insight into the molecular mechanisms involved in human prolactin receptor antagonist (hPRL-G129R)-induced apoptosis, we used real-time reverse transcription-polymerase chain reaction to measure bax and bcl-2 gene expression in 11 human breas
Publikováno v:
Oncogene. 21:5047-5055
To gain insight into the molecular basis of human prolactin (hPRL) antagonist induced apoptosis, we compared the differential gene expression profile of four human breast cancer cell lines following treatment with hPRL and its antagonist (hPRL-G129R)
Publikováno v:
Experimental cell research. 327(1)
Pattern recognition receptors (PRRs), e.g. toll receptors (TLRs) that bind ligands within the microbiome have been implicated in the pathogenesis of cancer. LPS is a ligand for two TLR family members, TLR4 and RP105 which mediate LPS signaling in B c
Autor:
Susan K. Peirce
Publikováno v:
The American Biology Teacher. 61:132-136
Autor:
Donald L. Durden, Susan K. Peirce, Anindya Dasgupta, Todd Cooper, Chengyu Prince, Harry W. Findley
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Studies of SF1126, an RGDS targeted, water-soluble prodrug of LY294002, are currently nearing completion in two adult Phase I trials. Herein, we performed a preclinical evaluation of SF1126 as a PI-3K inhibitor for Phase I trials in the treat
Autor:
Susan K. Peirce, Harry W. Findley
Publikováno v:
Oncology Reports. 22
MYCN gene amplification is a negative prognostic indicator in neuroblastoma and high level MycN expression in Stage IV neuroblastoma is generally a hallmark of poor patient outcome. However, high level expression of the MycN protein in neuroblastoma