Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Susan K, Vester"'
Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
Autor:
Kuan-Ying A. Huang, Xiaorui Chen, Arpita Mohapatra, Hong Thuy Vy Nguyen, Lisa Schimanski, Tiong Kit Tan, Pramila Rijal, Susan K. Vester, Rory A. Hills, Mark Howarth, Jennifer R. Keeffe, Alexander A. Cohen, Leesa M. Kakutani, Yi-Min Wu, Md Shahed-Al-Mahmud, Yu-Chi Chou, Pamela J. Bjorkman, Alain R. Townsend, Che Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
An antibody, IY-2A, identified from a panel of class-4 SARS-CoV-2-neutralizing antibodies isolated from convalescent and vaccinated individuals, targets and induces partial unfolding of a conserved epitope within the RBD. IY-2A retains activity again
Externí odkaz:
https://doaj.org/article/4fd4ed3b1b214dcab49cfc9d3f96eda6
Autor:
Susan K. Vester, Rolle Rahikainen, Irsyad N. A. Khairil Anuar, Rory A. Hills, Tiong Kit Tan, Mark Howarth
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The SpyCatcher-SpyTag system allows protein anchoring and nanoassembly. Here, the authors engineer SpySwitch, a dually switchable Catcher which allows gentle purification of SpyTagged proteins prior to downstream applications such as the assembly of
Externí odkaz:
https://doaj.org/article/bdaf544209824dad9f2d175eff328eec
Autor:
Susan K. Vester, Anna M. Davies, Rebecca L. Beavil, Balraj S. Sandhar, Andrew J. Beavil, Hannah J. Gould, Brian J. Sutton, James M. McDonnell
Publikováno v:
Antibodies, Vol 12, Iss 4, p 75 (2023)
We have previously produced a toolkit of antibodies, comprising recombinant human antibodies of all but one of the human isotypes, directed against the polcalcin family antigen Phl p 7. In this work, we complete the toolkit of human antibody isotypes
Externí odkaz:
https://doaj.org/article/d3b9137087384153b31f164c3220e2a6
Autor:
Christopher A. Odhams, Amy L. Roberts, Susan K. Vester, Carolina S. T. Duarte, Charlie T. Beales, Alexander J. Clarke, Sonja Lindinger, Samuel J. Daffern, Antonino Zito, Lingyan Chen, Leonardo L. Jones, Lora Boteva, David L. Morris, Kerrin S. Small, Michelle M. A. Fernando, Deborah S. Cunninghame Graham, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Systemic lupus erythematosus (SLE) shows a striking bias towards higher prevalence in females. Here, the authors perform fine-mapping of an SLE-associated locus at Xp21.2 and characterise a candidate gene, CXorf21, as IFN-responsive in immune cells t
Externí odkaz:
https://doaj.org/article/26e43468667241ccb8271a65e26175aa
Autor:
Susan K. Vester, Timothy J. Vyse
Publikováno v:
Genetics of Rare Autoimmune Diseases ISBN: 9783030039332
Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with a strong genetic component. Monogenic causes of SLE, such as complement deficiencies, are rare but have high penetrance and have been able to shed light on some dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f777d8c80ca12aa1d694174da94285b9
https://doi.org/10.1007/978-3-030-03934-9_1
https://doi.org/10.1007/978-3-030-03934-9_1
Autor:
Deborah S. Cunninghame Graham, James M. McDonnell, Andrew J. Beavil, Susan K. Vester, Rebecca L. Beavil, Steven Lynham, Timothy J. Vyse
Publikováno v:
The Journal of Biological Chemistry
The C1q and TNF related 4 (C1QTNF4) protein is a structurally unique member of the C1QTNF family, a family of secreted proteins that have structural homology with both complement C1q and the tumor necrosis factor superfamily. C1QTNF4 has been linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce0f5e80c43d070e0d52eeefea5867d
https://doi.org/10.1016/j.jbc.2021.100513
https://doi.org/10.1016/j.jbc.2021.100513
Autor:
Christopher A, Odhams, Amy L, Roberts, Susan K, Vester, Carolina S T, Duarte, Charlie T, Beales, Alexander J, Clarke, Sonja, Lindinger, Samuel J, Daffern, Antonino, Zito, Lingyan, Chen, Leonardo L, Jones, Lora, Boteva, David L, Morris, Kerrin S, Small, Michelle M A, Fernando, Deborah S, Cunninghame Graham, Timothy J, Vyse
Publikováno v:
Nature Communications
Systemic lupus erythematosus (SLE) is an autoimmune disease, characterised by increased expression of type I interferon (IFN)-regulated genes and a striking sex imbalance towards females. Through combined genetic, in silico, in vitro, and ex vivo app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b48291f06a2f99c7938a2b63e9c6bb01
https://pubmed.ncbi.nlm.nih.gov/31092820
https://pubmed.ncbi.nlm.nih.gov/31092820