Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Susan Jeong"'
1
Total syntheses of (+)- and (−)-syringolides 3 and of (+)- and (−)-syributins 1, 2 and 3
Autor: Catherine McCarty, Cristy Lindberg Benson, Mauricio Navarro Villalobos, Steven M. Zeman, Susan Jeong, John L. Wood, Matthew M. Weiss, Analee Salcedo, Jonathan Jenkins
Publikováno v: Tetrahedron. 65:8091-8098
The first total syntheses of (−)-syringolide 3, (+)-syributin 3 and their unnatural enantiomers (+)-syringolide 3 and (−)-syributin 3 using a common intermediate as starting material are described. In addition, total syntheses of (−)- and (+)-s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48c1a1599cd4e255f4dcd3c87dcf2c41
https://doi.org/10.1016/j.tet.2009.07.055
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2
Total Synthesis of Nominal Diazonamides—Part 1: Convergent Preparation of the Structure Proposed for (−)-Diazonamide A
Autor: Patrick G. Harran, Susan Jeong, Jing Li, Lothar Esser
Publikováno v: Angewandte Chemie. 113:4901-4906
Representative procedure for the preparation of 7: A solution of lithium hexamethyldisilazide in THF (1, 0.20 mL, 0.20 mmol) was added dropwise to a solution of 1 (0.038 g; 0.20 mmol) in THF (0.5 mL) at 78C. The resulting pale yellow solution was sti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a9b4e401064a018fd1d936ab9fc3eeb
https://doi.org/10.1002/1521-3757(20011217)113:24<4901::aid-ange4901>3.0.co
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3
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands
Autor: Karen S. Flatten, Lin Zhi, Rich A. Heyman, Susan Jeong, E. Adam Kallel, Glenn Croston, Luc J. Farmer, Alex M. Nadzan
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 7:2747-2752
A series of potent retinoid X receptor (RXR) selective ligands were designed and prepared. The lead compound 6a, showed good binding (Kd; 3–7 nM) and transactivation (EC50; 19–24 nM) to the RXR subfamily of retinoid receptors. More importantly, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae9f5e21f3e243b50d0c726d327d716a
https://doi.org/10.1016/s0960-894x(97)10079-8
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4
Synthesis and structure-activity relationships of potent retinoid X receptor ligands
Autor: Glenn Croston, Susan Jeong, Luc J. Farmer, Rich A. Heyman, Karen S. Flatten, E. Adam Kallel, Alex M. Nadzan, Stacie S. Canan Koch
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 7:2393-2398
A series of potent retinoid X receptor (RXR) selective ligands was designed and prepared. The lead compound 7a showed good binding (K i ; 20–50 nM) and transactivation (EC 50 ; 40–50 nM) to the RXR subfamily of retinoid receptors. More importantl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::075808c7d07ab7aa1987ca53d8063e54
https://doi.org/10.1016/s0960-894x(97)00437-x
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7
ChemInform Abstract: Total Synthesis of Nominal Diazonamides. Part 1. Convergent Preparation of the Structure Proposed for (-)-Diazonamide A
Autor: Jing Li, Susan Jeong, Patrick G. Harran, Lothar Esser
Publikováno v: ChemInform. 33
Representative procedure for the preparation of 7: A solution of lithium hexamethyldisilazide in THF (1, 0.20 mL, 0.20 mmol) was added dropwise to a solution of 1 (0.038 g; 0.20 mmol) in THF (0.5 mL) at 78C. The resulting pale yellow solution was sti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a60033675df27b2d61dc7391f7761b36
https://doi.org/10.1002/chin.200221205
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8
Retinoic acid receptor ligands based on the 6-cyclopropyl-2,4-hexadienoic acid
Autor: Susan Jeong, William W. Lamph, Glenn Croston, Lin Zhi, Karen S. Flatten, Luc J. Farmer, Deborah L. Osburn, Rich A. Heyman, Alex M. Nadzan
Publikováno v: Bioorganicmedicinal chemistry letters. 13(2)
A series of novel cyclopropanyl methyl hexadienoic acid retinoids was designed and prepared. These compounds exhibited either selective activity as RXR agonists or pan-agonists on one or more of each of the RAR and RXR isoforms. The most potent pan-a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8bc78f5625c6e8214435ced5d045ab
https://pubmed.ncbi.nlm.nih.gov/12482435
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10
Macrocyclic Triarylethylenes via Heck Endocyclization: A System Relevant to Diazonamide Synthesis
Autor: Susan Jeong, Xin Chen, Patrick G. Harran
Publikováno v: The Journal of Organic Chemistry. 63:8640-8641
Received September 3, 1998 Diazonamide A (1, Figure 1) and its congeners1 are impressive products of invertebrate secondary metabolism wherein at least three proteinogenic amino acids have been incorporated, perhaps by posttranslational modification
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::add81622c79d782076af6c461596ba34
https://doi.org/10.1021/jo981791e
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