Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Susan J. van Rensburg"'
Autor:
Susan J. van Rensburg, Armand V. Peeters, Ronald van Toorn, Johan Schoeman, Kelebogile E. Moremi, Carel J. van Heerden, Maritha J. Kotze
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 19, Iss , Pp - (2019)
Background: Multiple sclerosis is a disorder related to demyelination of axons. Iron is an essential cofactor in myelin synthesis. Previously, we described two children (males of mixed ancestry) with relapsing-remitting multiple sclerosis (RRMS) wher
Externí odkaz:
https://doaj.org/article/3936d27ade6948d296d3af5fe9270390
Autor:
Nicole van der Merwe, Armand V. Peeters, Fredrieka M. Pienaar, Juanita Bezuidenhout, Susan J. van Rensburg, Maritha J. Kotze
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 2, p 467 (2017)
Panel-based next generation sequencing (NGS) is currently preferred over whole exome sequencing (WES) for diagnosis of familial breast cancer, due to interpretation challenges caused by variants of uncertain clinical significance (VUS). There is also
Externí odkaz:
https://doaj.org/article/ccbf5bdc0c44471f9fd1de79fe689c44
Autor:
Olawande Daramola, Tatenda Duncan Kavu, Maritha J Kotze, Oiva Kamati, Zaakiyah Emjedi, Boniface Kabaso, Thomas Moser, Karl Stroetmann, Isaac Fwemba, Fisayo Daramola, Martha Nyirenda, Susan J van Rensburg, Peter S Nyasulu, Jeanine L Marnewick
Publikováno v:
Digital Health, Vol 9 (2023)
Background COVID-19 vaccines offer different levels of immune protection but do not provide 100% protection. Vaccinated persons with pre-existing comorbidities may be at an increased risk of SARS-CoV-2 breakthrough infection or reinfection. The aim o
Externí odkaz:
https://doaj.org/article/8b1345f7440247f2853c46e6b0f0e480
Autor:
Merlisa Kemp, Clint Johannes, Susan J van Rensburg, Martin Kidd, Ferial Isaacs, Maritha J Kotze, Penelope Engel-Hills
Publikováno v:
Journal of Medical Imaging and Radiation Sciences. 54:247-256
BackgroundAlthough multiple sclerosis (MS) is an immune-related disorder, pharmaceutical interventions targeting the immune system do not stop or reverse disability progression; the major challenge for this condition. Studies show that disability pro
Autor:
Coenraad J. Hattingh, Clint Johannes, Kelebogile E Moremi, Penelope Engel-Hills, Rajiv T Erasmus, Merlisa C Kemp, Susan J van Rensburg, Ronald van Toorn, Maritha J. Kotze
Publikováno v:
Metabolic Brain Disease. 36:1151-1167
In this Review (Part I), we investigate the scientific evidence that multiple sclerosis (MS) is caused by the death of oligodendrocytes, the cells that synthesize myelin, due to a lack of biochemical and nutritional factors involved in mitochondrial
Autor:
Rajiv T Erasmus, Aye Aye Khine, Ronald van Toorn, Kelebogile E Moremi, Mariaan Jaftha, Armand V. Peeters, Susan J van Rensburg, Coenraad J. Hattingh, Lindiwe Whati, Annalise E Zemlin, Felix Potocnik, Clint Johannes, Maritha J. Kotze, Penelope Engel-Hills, Merlisa C Kemp, Carel J. van Heerden
Publikováno v:
Metabolic Brain Disease. 36:1169-1181
In Part I of this Review we evaluated the scientific evidence for a Metabolic Model of multiple sclerosis (MS). Part II outlines the implementation of an adaptive pathology-supported genetic testing (PSGT) algorithm aimed at preventing/reversing disa
Autor:
Susan J, van Rensburg, Coenraad, Hattingh, Clint, Johannes, Kelebogile E, Moremi, Armand V, Peeters, Carel J, van Heerden, Rajiv T, Erasmus, Annalise E, Zemlin, Merlisa C, Kemp, Mariaan, Jaftha, Aye Aye, Khine, Felix C V, Potocnik, Lindiwe, Whati, Penelope, Engel-Hills, Ronald, van Toorn, Maritha J, Kotze
Publikováno v:
Metabolic brain disease. 36(6)
In Part I of this Review we evaluated the scientific evidence for a Metabolic Model of multiple sclerosis (MS). Part II outlines the implementation of an adaptive pathology-supported genetic testing (PSGT) algorithm aimed at preventing/reversing disa
Autor:
Susan J, van Rensburg, Ronald, van Toorn, Rajiv T, Erasmus, Coenraad, Hattingh, Clint, Johannes, Kelebogile E, Moremi, Merlisa C, Kemp, Penelope, Engel-Hills, Maritha J, Kotze
Publikováno v:
Metabolic brain disease. 36(6)
In this Review (Part I), we investigate the scientific evidence that multiple sclerosis (MS) is caused by the death of oligodendrocytes, the cells that synthesize myelin, due to a lack of biochemical and nutritional factors involved in mitochondrial
Autor:
Susan J. van Rensburg, Coenraad Hattingh, Clint Johannes, Kelebogile E. Moremi, Armand V. Peeters, Carel J. van Heerden, Rajiv T. Erasmus, Annalise E. Zemlin, Merlisa C. Kemp, Mariaan Jaftha, Aye Aye Khine, Felix C.V. Potocnik, Lindiwe Whati, Penelope Engel-Hills, Ronald van Toorn, Maritha J. Kotze
Publikováno v:
Metabolic Brain Disease. 36:1183-1184
Autor:
Penelope Engel-Hills, Christine Lochner, Martin Kidd, Jean-Paul Fouche, Susan J. van Rensburg, Coenraad J. Hattingh, Maritha J. Kotze, Estelle Herbert
Publikováno v:
Metabolic Brain Disease. 33:545-557
Multiple sclerosis (MS) is a disorder related to myelin damage, which can be investigated by neuroimaging techniques such as fractional anisotropy (FA), a measure of microstructural white matter properties. The objectives of this study were to invest