Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Susan J. Kim"'
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-40 (2024)
Abstract Neutrophil extracellular traps (NETs), crucial in immune defense mechanisms, are renowned for their propensity to expel decondensed chromatin embedded with inflammatory proteins. Our comprehension of NETs in pathogen clearance, immune regula
Externí odkaz:
https://doaj.org/article/99b6aa50367d455697943374cd2458f5
Autor:
Fabrizio E. Mancini, Paul E. A. Humphreys, Steven Woods, Nicola Bates, Sara Cuvertino, Julieta O’Flaherty, Leela Biant, Marco A. N. Domingos, Susan J. Kimber
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Osteoarthritis is the most common degenerative joint condition, leading to articular cartilage (AC) degradation, chronic pain and immobility. The lack of appropriate therapies that provide tissue restoration combined with the limited lifespa
Externí odkaz:
https://doaj.org/article/7f0785f7ef8b40a899ff7fca232187f7
Autor:
Paul E.A. Humphreys, Steven Woods, Nicola Bates, Kirsty M. Rooney, Fabrizio E. Mancini, Cerys Barclay, Julieta O’Flaherty, Franck P. Martial, Marco A.N. Domingos, Susan J. Kimber
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113502- (2023)
Summary: Optogenetics is a rapidly advancing technology combining photochemical, optical, and synthetic biology to control cellular behavior. Together, sensitive light-responsive optogenetic tools and human pluripotent stem cell differentiation model
Externí odkaz:
https://doaj.org/article/48364f8484364e76b3439618b536e1c7
Autor:
Joel B. Mason, Zhenhua Liu, Chi Guo, Huawei Zeng, Jinchao Li, Susan J. Kim, Yu Jin, Armina-Lyn M. Frederick
Publikováno v:
The Journal of Nutritional Biochemistry. 77:108302
Obesity is an established risk factor for colorectal cancer, but the mechanisms responsible for this relationship are not adequately delineated. Using a TNF-α-/- mouse model, the present study aimed to test the causal role of TNF-α in mediating the
Autor:
Frederick K. Kamanu, Joel B. Mason, Keith Leung, Laurence D. Parnell, Jimmy W. Crott, Gail Rogers, Anna C. Pfalzer, Albert K. Tai, M. Kyla Shea, Paloma E Garcia, Susan J. Kim, Zhenhua Liu
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 27(12)
Background: Obesity, a risk factor for colorectal cancer, raises systemic levels of proinflammatory mediators. Whether increased levels also reside in the colons of obese individuals and are accompanied by procancerous alterations in the mucosal tran
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionCerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is the most common genetic small vessel disease caused by variants in the NOTCH3 gene. Patients with CADASIL experience recurrent strokes
Externí odkaz:
https://doaj.org/article/41ebd091ac4e40059806aa8527dd856e
Autor:
Eric D Ciappio, Zhenhua Liu, Grace Bennett, Andrew S. Greenberg, Jimmy W. Crott, Joel B. Mason, Ryan S. Brooks, Susan J. Kim
Publikováno v:
The Journal of Nutritional Biochemistry. 23:1207-1213
Inflammation associated with obesity may play a role in colorectal carcinogenesis, but the underlying mechanism remains unclear. This study investigated whether the Wnt pathway, an intracellular signaling cascade that plays a critical role in colorec
Autor:
Susan J. Kim
Publikováno v:
String Research Journal. 1:39-54
Recent research in music education has found that college or conservatory students demonstrate similar self-regulated learning behaviors to those of professional musicians. Yet, how a musician becomes an expert is still unknown. The purpose of my stu
Autor:
Sophia A. Read, Chee Shuen Go, Miguel J. S. Ferreira, Cosimo Ligorio, Susan J. Kimber, Ahu G. Dumanli, Marco A. N. Domingos
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2432 (2023)
Naturally derived polysaccharide-based hydrogels, such as alginate, are frequently used in the design of bioinks for 3D bioprinting. Traditionally, the formulation of such bioinks requires the use of pre-reticulated materials with low viscosities, wh
Externí odkaz:
https://doaj.org/article/6a3d9f6f625546cf9c176b335ba2965e
Publikováno v:
The Journal of Experimental Medicine
Using human autoimmune sera as molecular probes, we previously described the association of phosphorylated serine/arginine splicing factors (SR splicing factors) with the U1-small nuclear ribonucleoprotein (U1-snRNP) and U3-small nucleolar RNP (snoRN