Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Susan J. Harkema"'
Autor:
Enrico Rejc, Simone Zaccaron, Collin Bowersock, Tanvi Pisolkar, Beatrice Ugiliweneza, Gail F. Forrest, Sunil Agrawal, Susan J. Harkema, Claudia A. Angeli
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 15, p 4309 (2024)
(1) Background. High-level spinal cord injury (SCI) disrupts trunk control, leading to an impaired performance of upright postural tasks in sitting and standing. We previously showed that a novel robotic postural stand training with spinal cord epidu
Externí odkaz:
https://doaj.org/article/d8417df4453240cc9c0da9a2fbea283c
Autor:
Daniel Medina-Aguiñaga, Robert F. Hoey, Natasha L. Wilkins, Beatrice Ugiliweneza, Jason Fell, Susan J. Harkema, Charles H. Hubscher
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Recent pre-clinical and clinical spinal cord epidural stimulation (scES) experiments specifically targeting the thoracolumbar and lumbosacral circuitries mediating lower urinary tract (LUT) function have shown improvements in storage, detrus
Externí odkaz:
https://doaj.org/article/38c35f99e0944758b6bb327bd112e2d9
Publikováno v:
IEEE Transactions on Neural Systems and Rehabilitation Engineering, Vol 31, Pp 3047-3054 (2023)
The aims of this study are to characterize the contamination of EMG signals by artifacts generated by the delivery of spinal cord transcutaneous stimulation (scTS) and to evaluate the performance of an Artifact Adaptive Ideal Filtering (AA-IF) techni
Externí odkaz:
https://doaj.org/article/df821df39011452bb95e3006ad1f7490
Autor:
Santosh Chandrasekaran, Nikunj A. Bhagat, Richard Ramdeo, Sadegh Ebrahimi, Pawan D. Sharma, Doug G. Griffin, Adam Stein, Susan J. Harkema, Chad E. Bouton
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Peripheral nerve injury can lead to chronic pain, paralysis, and loss of sensation, severely affecting quality of life. Spinal cord stimulation has been used in the clinic to provide pain relief arising from peripheral nerve injuries, however, its ab
Externí odkaz:
https://doaj.org/article/8fe697883d3f42e6bb47593682e82b2b
Autor:
Santosh Chandrasekaran, Nikunj A. Bhagat, Richard Ramdeo, Sadegh Ebrahimi, Pawan D. Sharma, Doug G. Griffin, Adam Stein, Susan J. Harkema, Chad E. Bouton
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Long-term recovery of limb function is a significant unmet need in people with paralysis. Neuromodulation of the spinal cord through epidural stimulation, when paired with intense activity-based training, has shown promising results toward restoring
Externí odkaz:
https://doaj.org/article/f65ae2cfb24a444e9d9ba720878f32db
Autor:
April N. Herrity, Sevda C. Aslan, Samineh Mesbah, Ricardo Siu, Karthik Kalvakuri, Beatrice Ugiliweneza, Ahmad Mohamed, Charles H. Hubscher, Susan J. Harkema
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Profound dysfunctional reorganization of spinal networks and extensive loss of functional continuity after spinal cord injury (SCI) has not precluded individuals from achieving coordinated voluntary activity and gaining multi-systemic autono
Externí odkaz:
https://doaj.org/article/b8b57357787d43d49db9fb13d284a7bc
Autor:
Robert F. Hoey, Daniel Medina-Aguiñaga, Fahmi Khalifa, Beatrice Ugiliweneza, Dengzhi Wang, Sharon Zdunowski, Jason Fell, Ahmed Naglah, Ayman S. El-Baz, April N. Herrity, Susan J. Harkema, Charles H. Hubscher
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Pre-clinical studies have shown that spinal cord epidural stimulation (scES) at the level of pelvic and pudendal nerve inputs/outputs (L5-S1) alters storage and/or emptying functions of both the bladder and bowel. The current mapping experim
Externí odkaz:
https://doaj.org/article/2945b87ac4844ba9bdf794cfc2c942df
Publikováno v:
Bioengineering, Vol 10, Iss 9, p 1065 (2023)
Cervical spinal cord injury (SCI) leads to impaired trunk motor control, negatively impacting the performance of activities of daily living in the affected individuals. Improved trunk control with better sitting posture has been previously observed d
Externí odkaz:
https://doaj.org/article/bcad29376a44449cb7ee492fbbd7535a
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
IntroductionPrevious studies support modular organization of locomotor circuitry contributing to the activation of muscles in a spatially and temporally organized manner during locomotion. Human spinal circuitry may reorganize after spinal cord injur
Externí odkaz:
https://doaj.org/article/ab14e84234fe40aeb309c22431c0d068
Autor:
Robert F. Hoey, Daniel Medina-Aguiñaga, Fahmi Khalifa, Beatrice Ugiliweneza, Sharon Zdunowski, Jason Fell, Ahmed Naglah, Ayman S. El-Baz, April N. Herrity, Susan J. Harkema, Charles H. Hubscher
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-21 (2021)
Abstract Spinal cord epidural stimulation (scES) mapping at L5-S1 was performed to identify parameters for bladder and bowel inhibition and/or contraction. Using spinally intact and chronic transected rats of both sexes in acute urethane-anesthetized
Externí odkaz:
https://doaj.org/article/69935db908644956bec5213faacd046d