Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan J. Boyd"'
Publikováno v:
Addiction. 107:1632-1638
Aims Concern about crime is a significant barrier to the establishment of methadone treatment centers (MTCs). Methadone maintenance reduces crime among those treated, but the relationship between MTCs and neighborhood crime is unknown. We evaluated c
Autor:
Christopher J. Endres, Kenzie L. Preston, Udi E. Ghitza, J. James Frost, Badreddine Bencherif, Hiroto Kuwabara, David H. Epstein, Susan J. Boyd, Marc L. Copersino, David A. Gorelick
Publikováno v:
Biological Psychiatry. 68:697-703
Background Cocaine users not seeking treatment have increased regional brain mu-opioid receptor (mOR) binding that correlates with cocaine craving and tendency to relapse. In cocaine-abusing outpatients in treatment, the relationship of mOR binding a
Autor:
Roy C. Ziegelstein, David A. Gorelick, Praveen Kanneganti, Richard A. Nelson, Marc L. Copersino, Susan J. Boyd
Publikováno v:
Journal of Addiction Medicine. 3:128-133
OBJECTIVES: : Cocaine use is associated with cardiac arrhythmias. Markers of ventricular late potentials, which may be a precursor to malignant ventricular arrhythmias, can be detected by signal-averaged electrocardiography (SA-ECG) but not by standa
Autor:
Robert F. Dannals, David A. Gorelick, Yu Kyeong Kim, Marc L. Copersino, J. James Frost, Susan J. Boyd, Badreddine Bencherif, Richard A. Nelson
Publikováno v:
Psychopharmacology. 200:475-486
Cocaine users have increased regional brain mu-opioid receptor (mOR) binding which correlates with cocaine craving. The relationship of mOR binding to relapse is unknown.To evaluate regional brain mOR binding as a predictor of relapse to cocaine use
Publikováno v:
Drug and Alcohol Dependence. 95:160-163
Cocaine lengthens electrocardiographic QTc, QRS and PR intervals through blockade of sodium and potassium channels, but changes during withdrawal have not been well studied.We recorded weekly electrocardiograms (ECGs) from 25 physically healthy cocai
Publikováno v:
The American Journal of Drug and Alcohol Abuse. 34:489-498
We compared treadmill exercise stress testing (EST) in 28 medically screened, chronic cocaine users with the cardiovascular effects of an IV cocaine challenge (25 mg or 50 mg). All subjects had a clinically normal EST and echocardiography (except 2 s
Autor:
Gerard Le Fur, Kenzie L. Preston, Marilyn A. Huestis, Stephen J. Heishman, Denis Bonnet, Susan J. Boyd, David A. Gorelick
Publikováno v:
Psychopharmacology. 194:505-515
A single 90-mg dose of the cannabinoid CB1 receptor antagonist rimonabant attenuates effects of smoked cannabis in humans.The objective of this study is to evaluate whether repeated daily 40-mg doses of rimonabant can attenuate effects of smoked cann
Autor:
Li Juan Fang, Kevin M. Armstrong, Deborah R. Medoff, Lisa B. Dixon, Susan J. Boyd, David A. Gorelick
Publikováno v:
Social Science Computer Review. 25:163-173
Whether substance abuse treatment centers affect neighborhood crime is hotly debated. Empirical evidence on this issue is lacking because of the difficulty of distinguishing the crime effect of treatment centers in high-crime areas, the inability to
Autor:
Caryn Lerman, Wallace B. Pickworth, Susan J. Boyd, Andrew J. Waters, Adam M. Leventhal, Eric T. Moolchan
Publikováno v:
Experimental and Clinical Psychopharmacology. 15:21-36
Gender differences in tobacco withdrawal are of considerable clinical importance, but research findings on this topic have been mixed. Methodological variation in samples sizes, experimental design, and measures across studies may explain the inconsi
Autor:
Jean Lud Cadet, Charles R. Schuster, Richard A. Nelson, Ronald I. Herning, Carlo Contoreggi, Jack E. Henningfield, David A. Gorelick, Susan J. Boyd, Roy C. Ziegelstein
Publikováno v:
Drug and Alcohol Dependence. 82:19-24
The rate hypothesis of psychoactive drug action holds that the faster a drug reaches the brain and starts to act, the greater its reinforcing effects and abuse liability. A previous human study using a single cocaine dose confirmed the rate hypothesi