Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Susan J. Blakeney"'
Autor:
Robert J. Visalli, Min Guo, Deborah Long, Jacek Kowalski, Donna Tummolo, Robert J. Natuk, David K. C. Cooper, Susan J. Blakeney, Timothy J. Zamb, Seema S Gangolli, Joanne DeStefano
Publikováno v:
Journal of Virology. 79:10498-10506
A herpes simplex virus type 2 (HSV-2) UL24 β-glucuronidase (UL24-βgluc) insertion mutant was derived from HSV-2 strain 186 via standard marker transfer techniques. Cell monolayers infected with UL24-βgluc yielded cytopathic effect with syncytium f
Publikováno v:
Virology. 308(2):216-224
Expression of Norwalk virus nonstructural polyprotein precursor in vitro resulted in rapid cotranslational cleavage at specific sites. The cleavage products were similar to those previously identified for Southampton virus, a highly related virus. We
Autor:
Sylvia DeBruin, Kristin R Kourie, Duzhang Zhu, John H. Eldridge, Susan J. Blakeney, Timothy J. Zamb, Sangeeta B. Periwal, Nandini Ramachandaran, Khushroo E. Shroff, Patricia A Reilly, Steve Udem, Larry R. Smith
Publikováno v:
Vaccine. 21:376-385
In this study, we evaluated the potential of a genetically modified cholera toxin, CT-E29H as an adjuvant for recombinant Norwalk virus like particle (NV-VLP) vaccine. This detoxified mutant, containing E to H substitution at amino acid 29 of the CT-
Autor:
David A. Cooper, Susan J. Blakeney, Robert J. Natuk, Min Guo, Robert J. Visalli, Jacek Kowalski, Seema S Gangolli
Publikováno v:
Vaccine. 32(12)
The rational design and development of genetically attenuated HSV-2 mutant viruses represent an attractive approach for developing both prophylactic and therapeutic vaccines for genital herpes. Previously, HSV-2 UL24 was shown to be a virulence deter