Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Susan J. Bickerton"'
Autor:
Kyoko Nakamura, Neil H. James, Paul Farrington, Ankur Karmokar, Susan J. Bickerton, Simon J. Dovedi, Gareth Hughes, Timothy M Illidge, Elaine Cadogan, Antonio Ramos-Montoya, Barry R. Davies, Viia Valge-Archer
Publikováno v:
Nakamura, K, Karmokar, A, Farrington, P M, James, N H, Ramos-Montoya, A, Bickerton, S J, Hughes, G D, Illidge, T M, Cadogan, E B, Davies, B R, Dovedi, S J & Valge-Archer, V 2021, ' Inhibition of DNA-PK with AZD7648 Sensitizes Tumor Cells to Radiotherapy and Induces Type I IFN-Dependent Durable Tumor Control ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 27, no. 15, pp. 4353-4366 . https://doi.org/10.1158/1078-0432.CCR-20-3701
Purpose: Combining radiotherapy (RT) with DNA damage response inhibitors may lead to increased tumor cell death through radiosensitization. DNA-dependent protein kinase (DNA-PK) plays an important role in DNA double-strand break repair via the nonhom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361b99c301898bba1de98f81587a182c
https://research.manchester.ac.uk/en/publications/08e42339-29d6-407b-83fc-396678da590e
https://research.manchester.ac.uk/en/publications/08e42339-29d6-407b-83fc-396678da590e
Autor:
Yafei Chen, Manisha Sonee, Susan J. Bickerton, James Eric McDuffie, Adeyemi O Adedeji, Tony Pourmohamad, Catherine J. Betts, Jennifer Burkey
Publikováno v:
International Journal of Toxicology. 38:12-22
Novel urinary protein biomarkers have recently been identified and qualified in rats for the early detection of renal injury in drug development studies. However, there seems to be no standardized normalization method for analyzing these urinary biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e44125efb8f8e2e336bcabbf356a1b
https://doi.org/10.1177/1091581818819791
https://doi.org/10.1177/1091581818819791
Autor:
Michelle Moores, Huw B. Jones, Susan J. Bickerton, Helen T. Thomas, Nicola Derbyshire, Lisa D. Burdett, Catherine J. Betts, Mark Pinches
Publikováno v:
Toxicologic Pathology. 40:522-533
A number of novel urinary biomarkers have been identified and partially qualified for use as markers for renal injury in rats. We use two novel multiplex assays to quantify biomarker concentration in multiple urine collections made prior to and follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37fea99070fdc68516523b350d71722
https://doi.org/10.1177/0192623311432438
https://doi.org/10.1177/0192623311432438
Autor:
Michelle Moores, Sally A. Price, Nicola Derbyshire, Lias D. Burdett, Laura Beattie, Catherine J. Betts, Mark Pinches, Susan J. Bickerton, Helen T. Thomas
Publikováno v:
Toxicologic pathology. 40(3)
A number of novel urinary biomarkers have been identified and partially qualified for use as markers for renal injury in rats. We used two multiplex assays for these novel biomarkers to quantify biomarker concentration in serial urine collections fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8c36f12c4286c2d43ff8cfa2e41afc
https://pubmed.ncbi.nlm.nih.gov/22395790
https://pubmed.ncbi.nlm.nih.gov/22395790
Autor:
Catherine J. Betts, Mark Pinches, Michelle Moores, Nicola Derbyshire, Lisa D. Burdett, Laura Beattie, Helen T. Thomas, Susan J. Bickerton
Publikováno v:
Toxicologic pathology. 40(3)
A number of novel urinary biomarkers have been identified and partially qualified for use as markers for renal injury in rats. To date, all evaluation studies have been made using 18 to 24 hour collection periods. However, shorter, more welfare frien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86213426c58883466f851a5caceab2ae
https://pubmed.ncbi.nlm.nih.gov/22246543
https://pubmed.ncbi.nlm.nih.gov/22246543