Výsledky vyhledávání - "Susan J. Land"

Akademický článek

Using Drosophila melanogaster as a model for genotoxic chemical mutational studies with a new program, SnpSift

Autor: Douglas Mark Ruden, Pablo eCingolani, Viral M Patel, Melissa eCoon, Tung eNguyen, Susan J Land, Xiangyi eLu

Publikováno v: Frontiers in Genetics, Vol 3 (2012)

This paper describes a new program SnpSift for filtering differential DNA sequence variants between two or more experimental genomes after genotoxic chemical exposure. Here, we illustrate how SnpSift can be used to identify candidate phenotype-releva

Externí odkaz: https://doaj.org/article/aa7b18b9fbc8423ab1c66a34ca3e8c87

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Akademický článek

BDNF val66met polymorphism influences age differences in microstructure of the corpus callosum

Autor: Kristen M Kennedy, Karen M Rodrigue, Susan J Land, Naftali Raz

Publikováno v: Frontiers in Human Neuroscience, Vol 3 (2009)

Brain-derived neurotrophic factor (BDNF) plays an important role in neuroplasticity and promotes axonal growth, but its secretion, regulated by a BDNF gene, declines with age. The low-activity (met) allele of common polymorphism BDNF val66met is asso

Externí odkaz: https://doaj.org/article/82017bb4cef149f38f09b772c45b0df9

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Akademický článek

Brain-derived neurotrophic factor Val66Met and blood glucose: a synergistic effect on memory

Autor: Naftali Raz, Cheryl L Dahle, Karen M Rodrigue, Kristen M Kennedy, Susan J Land, Bradley S Jacobs

Publikováno v: Frontiers in Human Neuroscience, Vol 2 (2008)

Age-related declines in episodic memory performance are frequently reported, but their mechanisms remain poorly understood. Although several genetic variants and vascular risk factors have been linked to mnemonic performance in general and age differ

Externí odkaz: https://doaj.org/article/b14ba2f967fe49619ae1a3d131025466

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Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells

Autor: Michael Kundi, Firouz Darroudi, Ratna Sanyal, Wolfram Parzefall, Siegfried Knasmüller, Susan J. Land, Ching Y. Wang, Christina E. Schwab

Publikováno v: Mutagenesis. 14:533-540

In order to study the mutagenic effects of heterocyclic aromatic amines (HAAs) in cells of human origin, five compounds, namely 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ), 2-amino-3, 4-dimethyl-imidazo[4,5-f]quinoline (MeIQ), 2-amino-3, 8-dimethyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7d823c9fe70113d88203905970657a
https://doi.org/10.1093/mutage/14.6.533

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