Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Susan J Plott"'
Autor:
Ronald J. Voll, Michael A. Wassef, Jeffrey S. Stehouwer, Clinton D. Kilts, Michael J. Owens, Chase H. Bourke, Susan J Plott, Mark M. Goodman, Matthew S. Birnbaum
Publikováno v:
Bioorganic & Medicinal Chemistry. 28:115660
Autor:
Ping Helen Chen, Lauryn M. Daniel, John R. Votaw, Michael J. Owens, Lawrence E. Williams, Jeffrey S. Stehouwer, Mark M. Goodman, Susan J Plott, Leonard L. Howell, Ronald J. Voll
Publikováno v:
Journal of Medicinal Chemistry. 53:5549-5557
The N-(E)-fluorobutenyl-3beta-(para-halo-phenyl)nortropanes 9-12 were synthesized as ligands of the dopamine transporter (DAT) for use as (18)F-labeled positron emission tomography (PET) imaging agents. In vitro competition binding assays demonstrate
Autor:
Chase H. Bourke, Jeffrey S. Stehouwer, Susan J Plott, Ronald J. Voll, Michael A. Wassef, Clinton D. Kilts, Michael J. Owens, Mark M. Goodman, Matthew S. Birnbaum
Publikováno v:
Bioorganicmedicinal chemistry. 23(15)
A series of 3-(2,4-dichlorophenyl)-N-alkyl-N-fluoroalkyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amines were synthesized and evaluated as potential positron emission tomography (PET) tracers for the corticotropin-releasing factor type-1 (CRF1) recepto
Autor:
Jay D. Kranzler, Susan J Plott, Srinivas G. Rao, Charles B. Nemeroff, S.Neil Vaishnavi, Michael J. Owens
Publikováno v:
Biological Psychiatry. 55:320-322
Background Though selective serotonin reuptake inhibitors have revolutionized the field of psychiatry with demonstrated efficacy in affective and anxiety disorders with minimal side effects, norepinephrine-serotonin reuptake inhibitors may provide ef
Autor:
Stan Krulewicz, Susan J Plott, Michael J. Owens, Michael E. Thase, Charles B. Nemeroff, Jeffrey S. Simon, David J. Carpenter, David V. Sheehan
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 33(13)
Paroxetine and venlafaxine are potent serotonin transporter (SERT) antagonists and weaker norepinephrine transporter (NET) antagonists. However, the relative magnitude of effect at each of these sites during treatment is unknown. Using a novel blood