Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Susan J Little"'
Autor:
Seth C Inzaule, Mark J Siedner, Susan J Little, Santiago Avila-Rios, Alisen Ayitewala, Ronald J Bosch, Vincent Calvez, Francesca Ceccherini-Silberstein, Charlotte Charpentier, Diane Descamps, Susan H Eshleman, Joseph Fokam, Lisa M Frenkel, Ravindra K Gupta, John P A Ioannidis, Pontiano Kaleebu, Rami Kantor, Seble G Kassaye, Sergei L Kosakovsky Pond, Vinie Kouamou, Roger D Kouyos, Daniel R Kuritzkes, Richard Lessells, Anne-Genevieve Marcelin, Lawrence Mbuagbaw, Brian Minalga, Nicaise Ndembi, Richard A Neher, Roger Paredes, Deenan Pillay, Elliot G Raizes, Soo-Yon Rhee, Douglas D Richman, Kiat Ruxrungtham, Pardis C Sabeti, Jonathan M Schapiro, Sunee Sirivichayakul, Kim Steegen, Wataru Sugiura, Gert U van Zyl, Anne-Mieke Vandamme, Annemarie M J Wensing, Joel O Wertheim, Huldrych F Gunthard, Michael R Jordan, Robert W Shafer
Publikováno v:
PLoS Medicine, Vol 20, Iss 9, p e1004293 (2023)
• Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug resistance leads to the requirement for antiretroviral drugs that
Externí odkaz:
https://doaj.org/article/c16a34440b374c53938659e86b679144
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009336 (2021)
HIV molecular epidemiology estimates the transmission patterns from clustering genetically similar viruses. The process involves connecting genetically similar genotyped viral sequences in the network implying epidemiological transmissions. This tech
Externí odkaz:
https://doaj.org/article/19d0493ddfa44a4b91f02b81ec4c2533
Autor:
Karine Dubé, Sara Gianella, Susan Concha-Garcia, Susan J Little, Andy Kaytes, Jeff Taylor, Kushagra Mathur, Sogol Javadi, Anshula Nathan, Hursch Patel, Stuart Luter, Sean Philpott-Jones, Brandon Brown, Davey Smith
Publikováno v:
BMC Medical Ethics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background The U.S. National Institute of Allergies and Infectious Diseases (NIAID) and the National Institute of Mental Health (NIMH) have a new research priority: inclusion of terminally ill persons living with HIV (PLWHIV) in HIV cure-rel
Externí odkaz:
https://doaj.org/article/b8ecaedbf4eb4122bab3a0256762527c
Autor:
Michael Bobardt, Joseph Kuo, Udayan Chatterji, Sumit Chanda, Susan J Little, Norbert Wiedemann, Gregoire Vuagniaux, Philippe A Gallay
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211746 (2019)
Antiretroviral therapy (ART) suppresses HIV replication, but does not cure the infection because replication-competent virus persists within latently infected CD4+ T cells throughout years of therapy. These reservoirs contain integrated HIV-1 genomes
Externí odkaz:
https://doaj.org/article/631ad312baca467bacc1798777b5328e
Autor:
Michelli F Oliveira, Antoine Chaillon, Masato Nakazawa, Milenka Vargas, Scott L Letendre, Matthew C Strain, Ronald J Ellis, Sheldon Morris, Susan J Little, Davey M Smith, Sara Gianella
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006112 (2017)
Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to inflammation, brain damage and neurocognitive impairment. Paired blood and cerebrospinal flui
Externí odkaz:
https://doaj.org/article/e64e0181545249f8899dc1b0e0bd5b36
Autor:
Martin Hoenigl, Antoine Chaillon, Harald H Kessler, Bernhard Haas, Evelyn Stelzl, Karin Weninger, Susan J Little, Sanjay R Mehta
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151478 (2016)
To gain deeper insight into the epidemiology of HIV-1 transmission in South-East Austria we performed a retrospective analysis of 259 HIV-1 partial pol sequences obtained from unique individuals newly diagnosed with HIV infection in South-East Austri
Externí odkaz:
https://doaj.org/article/8ae8093daabb49f08226cc78d55c71b6
Autor:
Eun-Young Kim, Ramon Lorenzo-Redondo, Susan J Little, Yoon-Seok Chung, Prabhjeet K Phalora, Irina Maljkovic Berry, John Archer, Sudhir Penugonda, Will Fischer, Douglas D Richman, Tanmoy Bhattacharya, Michael H Malim, Steven M Wolinsky
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004281 (2014)
Human APOBEC3 proteins are cytidine deaminases that contribute broadly to innate immunity through the control of exogenous retrovirus replication and endogenous retroelement retrotransposition. As an intrinsic antiretroviral defense mechanism, APOBEC
Externí odkaz:
https://doaj.org/article/370d1a339d744cdda8e3f55d1c1c4c79
Autor:
Susan J Little, Sergei L Kosakovsky Pond, Christy M Anderson, Jason A Young, Joel O Wertheim, Sanjay R Mehta, Susanne May, Davey M Smith
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98443 (2014)
To reconstruct the local HIV-1 transmission network from 1996 to 2011 and use network data to evaluate and guide efforts to interrupt transmission.HIV-1 pol sequence data were analyzed to infer the local transmission network.We analyzed HIV-1 pol seq
Externí odkaz:
https://doaj.org/article/73ac2e8b86284b9192a34e14599f9433
Autor:
George K Hightower, Susanne J May, Josué Pérez-Santiago, Mary E Pacold, Gabriel A Wagner, Susan J Little, Douglas D Richman, Sanjay R Mehta, Davey M Smith, Sergei L Kosakovsky Pond
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68188 (2013)
Characterize intra-individual HIV-1 subtype B pol evolution in antiretroviral naive individuals.Longitudinal cohort study of individuals enrolled during primary infection.Eligible individuals were antiretroviral naïve participants enrolled in the co
Externí odkaz:
https://doaj.org/article/aa030d6e62c14c14930b286e08373300
Autor:
Myres W Tilghman, Susanne May, Josué Pérez-Santiago, Caroline C Ignacio, Susan J Little, Douglas D Richman, Davey M Smith
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35401 (2012)
To develop a low cost method to screen for virologic failure of antiretroviral therapy (ART) and HIV-1 drug resistance, we performed a retrospective evaluation of a screening assay using serial dilutions of HIV-1 RNA-spiked blood plasma and samples f
Externí odkaz:
https://doaj.org/article/6da2f3b2daaf499196d5819059370244