Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Susan J, Hsiao"'
Autor:
Ladan Fazlollahi, MD, Susan J. Hsiao, MD, PhD, Mahesh M. Mansukhani, MD, Julia L. Glade Bender, MD, Andrew L. Kung, MD, PhD, Darrell J. Yamashiro, MD, PhD, Helen E. Remotti, MD
Publikováno v:
Human Pathology: Case Reports, Vol 12, Iss C, Pp 42-47 (2018)
Malignant rhabdoid tumors (MRT) represent a distinct group of aggressive tumors usually occurring in infancy involving a variety of anatomic locations including the kidney, brain, soft tissue and liver. The molecular hallmark of these tumors is the p
Externí odkaz:
https://doaj.org/article/dc27268e4e3543e79f9438027a079702
Autor:
Tatyana, Gindin, Susan J, Hsiao
Publikováno v:
Clinics in Laboratory Medicine. 42:395-408
This article covers analytical principles of cancer next generation sequencing (NGS). Cancer samples require special considerations due to the cancer-specific applications of testing, as well as cancer sample specific issues, including low input, low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178ac9411c83ea612d913a70ccb972d3
https://doi.org/10.1016/j.cll.2022.04.003
https://doi.org/10.1016/j.cll.2022.04.003
Autor:
Jiuhong Pang, Hongai Xia, Shijun Mi, Wen Zhang, Danielle Pendrick, Christopher Freeman, Helen Fernandes, Mahesh Mansukhani, Susan J Hsiao
Publikováno v:
Journal of Clinical Pathology. 76:276-280
Tumour mutational burden (TMB) is used to predict response to immunotherapies. Although several groups have proposed calculation methods for TMB, a clear consensus has not yet emerged. In this study, we explored TMB calculation approaches with a 586-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64cd74e16572e930afaef5f9d1fd8bff
https://doi.org/10.1136/jcp-2022-208385
https://doi.org/10.1136/jcp-2022-208385
Publikováno v:
Cancer Genetics. :47-52
Targetable NTRK gene fusions can be detected across tumor types using methodologies such as pan-TRK IHC, DNA or RNA NGS testing, or FISH. Challenges for implementation of clinical testing for NTRK fusions may arise due to the range in NTRK fusion pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12bf3c8bffc9a897d25986db8bd9cca
https://doi.org/10.1016/j.cancergen.2021.12.010
https://doi.org/10.1016/j.cancergen.2021.12.010
Autor:
Mark D. Ewalt, Susan J. Hsiao
Publikováno v:
Surgical Pathology Clinics. 14:359-368
Pre-analytical factors in molecular oncology diagnostics are reviewed. Issues around sample collection, storage, and transport that might affect the stability of nucleic acids and the ability to perform molecular testing are addressed. In addition, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b741192ef9b1bc9b4bff4aeafff623b1
https://doi.org/10.1016/j.path.2021.05.001
https://doi.org/10.1016/j.path.2021.05.001
Autor:
Lianna J. Marks, Jennifer A. Oberg, Danielle Pendrick, Anthony N. Sireci, Chana Glasser, Carrie Coval, Rebecca J. Zylber, Wendy K. Chung, Jiuhong Pang, Andrew T. Turk, Susan J. Hsiao, Mahesh M. Mansukhani, Julia L. Glade Bender, Andrew L. Kung, Maria Luisa Sulis
Publikováno v:
Frontiers in Pediatrics, Vol 5 (2017)
BackgroundThe advent of comprehensive genomic profiling has markedly advanced the understanding of the biology of pediatric hematological malignancies, however, its application to clinical care is still unclear. We present our experience integrating
Externí odkaz:
https://doaj.org/article/72d22ad9cdc54209a38fa6c39fc9b294
Autor:
Susan J. Hsiao, Anthony N. Sireci, Richard D. Carvajal, Brian S. Henick, Mahesh Mansukhani, Helen Fernandes, Danielle Pendrick, Christopher E. Freeman, Jennifer A. Oberg, Gary K. Schwartz, Kevin A. Roth
Publikováno v:
JCO Precision Oncology. :1038-1048
PURPOSE The routine use of large next-generation sequencing (NGS) pan-cancer panels is required to identify the increasing number of, but often uncommon, actionable alterations to guide therapy. Inconsistent coverage and variable payment is hindering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8370de52761fb12f960ad85dc50f90e
https://doi.org/10.1200/po.20.00048
https://doi.org/10.1200/po.20.00048
Autor:
Marie C. Smithgall, Susan J. Hsiao, Helen Remotti, Mahesh Mansukhani, Helen Fernandes, Xiaolin Liu-Jarin
Publikováno v:
Human pathology. 119
Summary Gynecologic cancers are routinely screened for DNA mismatch repair (MMR) gene mutations using immunohistochemistry (IHC) and/or polymerase chain reaction (PCR) for microsatellite instability (MSI) to enable selection of immune checkpoint inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e606f8403ff9a3e6ef7064da12456f
https://pubmed.ncbi.nlm.nih.gov/34666078
https://pubmed.ncbi.nlm.nih.gov/34666078
Autor:
Mark D, Ewalt, Susan J, Hsiao
Publikováno v:
Surgical pathology clinics. 14(3)
Pre-analytical factors in molecular oncology diagnostics are reviewed. Issues around sample collection, storage, and transport that might affect the stability of nucleic acids and the ability to perform molecular testing are addressed. In addition, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19e21b65726bff235773d73d956a8d86
https://pubmed.ncbi.nlm.nih.gov/34373088
https://pubmed.ncbi.nlm.nih.gov/34373088
Publikováno v:
The Journal of Molecular Diagnostics : JMD
Chromosomal rearrangements involving the NTRK1, NTRK2, and NTRK3 genes (NTRK genes), which encode the high-affinity nerve growth factor receptor (TRKA), brain-derived neurotrophic factor/neurotrophin-3 (BDNF/NT-3) growth factor receptor (TRKB), and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de94bd5ebee0233f67f947998853e2a6
http://europepmc.org/articles/PMC7456740
http://europepmc.org/articles/PMC7456740