Výsledky vyhledávání - "Susan H. Camacho"

Tumor Vascular Response to Photodynamic Therapy and the Antivascular Agent 5,6-Dimethylxanthenone-4-Acetic Acid: Implications for Combination Therapy

Autor: David A. Bellnier, Richard T. Cheney, Joseph A. Spernyak, Richard Mazurchuk, Allan R. Oseroff, Susan H. Camacho, Mukund Seshadri

Publikováno v: Clinical Cancer Research. 11:4241-4250

Purpose: Photodynamic therapy (PDT) is a clinically approved treatment for a variety of solid malignancies. 5,6-Dimethylxanthenone-4-acetic acid (DMXAA) is a potent vascular targeting agent that has been shown to be effective against a variety of exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6cd99aaf2ec7554f61c5906d381881
https://doi.org/10.1158/1078-0432.ccr-04-2703

Zobrazit plný text záznamu

Synthesis, Photophysical Properties, Tumor Uptake, and Preliminary in Vivo Photosensitizing Efficacy of a Homologous Series of 3-(1‘-Alkyloxy)ethyl-3-devinylpurpurin-18-N-alkylimides with Variable Lipophilicity

Autor: Guosheng Wang, David A. Bellnier, Michael A. J. Rodgers, Joseph R. Missert, Thomas J. Dougherty, Susan H. Camacho, William R. Potter, Barbara W. Henderson, Ravindra K. Pandey, Gang Zheng

Publikováno v: Journal of Medicinal Chemistry. 44:1540-1559

Starting from methylpheophorbide-a, a homologous series of purpurinimides containing alkyl substituents at two different positions [as 3-(1(1)-O-alkyl) and 13(2)-N-alkyl] were synthesized. These compounds with variable lipophilicity (log P 5.32-16.44

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73694679774306eb85c18c193905318a
https://doi.org/10.1021/jm0005510

Zobrazit plný text záznamu

pH-Dependent Chalcogenopyrylium Dyes as Potential Sensitizers for Photodynamic Therapy: Selective Retention in Tumors by Exploiting pH Differences between Tumor and Normal Tissue

Autor: David N. Young, Michael R. Detty, Susan H. Camacho, Allan R. Oseroff, David A. Bellnier

Publikováno v: Photochemistry and Photobiology. 70:630-636

Ideal photosensitizers have long-wavelength absorption and strong tumor selectivity with rapid clearance from normal tissues. The telluroselenopyrylium dye 1 that absorbs light at 795 nm (epsilon = 285,000 M-1 cm-1) has a novel property that enhances

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91523aa542a223a9d610cd95168caff9
https://doi.org/10.1111/j.1751-1097.1999.tb08262.x

Zobrazit plný text záznamu

The Anatomic Site of Photodynamic Therapy is a Determinant for Immunosuppression in a Murine Model

Autor: David A. Musser, Patricia A. Manderscheid, Allan R. Oseroff, Susan H. Camacho

Publikováno v: Photochemistry and Photobiology. 69:222-225

The role of the irradiation site in the induction of suppression of the contact hypersensitivity (CHS) response following photodynamic therapy (PDT) was examined in a murine model. Laser irradiation on the flanks of nontumor-bearing Photofrin-injecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e3ad8f949a048e7454ea3c651c25e9b
https://doi.org/10.1111/j.1751-1097.1999.tb03277.x

Zobrazit plný text záznamu

Multiparameter flow cytometry for the diagnosis and monitoring of small GPI-deficient cellular populations

Autor: Susan H. Camacho, Petr Starostik, Minoo Battiwalla, Mehmet Hepgur, Paul K. Wallace, Dalin Pan, Manmeet S. Ahluwalia, Philip L. McCarthy

Publikováno v: Cytometry. Part B, Clinical cytometry. 78(5)

Background: Glycosyl-phosphatidylinositol (GPI)-negative blood cells are diagnostic for Paroxysmal Nocturnal Hemoglobinuria (PNH). Marrow failure states are often associated with GPI-negative cell populations. Quantification of small clonal populatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09e11992c5177ba7976b40dbd4ae5d7
https://pubmed.ncbi.nlm.nih.gov/20533383

Zobrazit plný text záznamu

Treatment with the tumor necrosis factor-alpha-inducing drug 5,6-dimethylxanthenone-4-acetic acid enhances the antitumor activity of the photodynamic therapy of RIF-1 mouse tumors

Autor: David A, Bellnier, Sandra O, Gollnick, Susan H, Camacho, William R, Greco, Richard T, Cheney

Publikováno v: Cancer research. 63(22)

DMXAA (5,6-dimethylxanthenone-4-acetic acid) is an antivascular agent that exerts its antitumor effect at least partly through the induction of tumor necrosis factor (TNF)-alpha. Photodynamic therapy (PDT), the activation of a photoreactive drug in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::413d05653b04643493cc67bc7a2fefd1
https://pubmed.ncbi.nlm.nih.gov/14633671

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání