Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Susan H Garfield"'
Autor:
Richard J Chen, Guofeng Zhang, Susan H Garfield, Yi-Jun Shi, Kevin G Chen, Pamela G Robey, Richard D Leapman
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142554 (2015)
Human pluripotent stem cells (hPSCs) represent very promising resources for cell-based regenerative medicine. It is essential to determine the biological implications of some fundamental physiological processes (such as glycogen metabolism) in these
Externí odkaz:
https://doaj.org/article/e9074ddc6fb94cb59548317c753f2712
Autor:
Yuwei Zhang, Rodrigo Calado, Mahadev Rao, Julie A Hong, Alan K Meeker, Bogdan Dumitriu, Scott Atay, Peter J McCormick, Susan H Garfield, Danny Wangsa, Hesed M Padilla-Nash, Sandra Burkett, Mary Zhang, Tricia F Kunst, Nathan R Peterson, Sichuan Xi, Suzanne Inchauste, Nasser K Altorki, Alan G Casson, David G Beer, Curtis C Harris, Thomas Ried, Neal S Young, David S Schrump
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101010 (2014)
BACKGROUND:Although implicated in the pathogenesis of several chronic inflammatory disorders and hematologic malignancies, telomerase mutations have not been thoroughly characterized in human cancers. The present study was performed to examine the fr
Externí odkaz:
https://doaj.org/article/30929f09818e42f1be6eb5742eaa3c96
Autor:
Kundan Sengupta, Madhvi B Upender, Linda Barenboim-Stapleton, Quang Tri Nguyen, Stephen M Wincovitch, Susan H Garfield, Michael J Difilippantonio, Thomas Ried
Publikováno v:
PLoS ONE, Vol 2, Iss 2, p e199 (2007)
BACKGROUND:Chromosomal aneuploidy is a defining feature of carcinomas. For instance, in colon cancer, an additional copy of Chromosome 7 is not only observed in early pre-malignant polyps, but is faithfully maintained throughout progression to metast
Externí odkaz:
https://doaj.org/article/a56d65d5a2784dd79c7474b4b6bec7ab
Autor:
Stuart H. Yuspa, Suresh V. Ambudkar, David J. Maloney, Susan H. Garfield, Andrew Lee, Suneet Shukla, Luowei Li
Ingenol-3-angelate (Ing3A), extracted from Euphorbia peplus, is currently in clinical trials for eradicating basal cell carcinoma, actinic keratosis, and squamous cell carcinoma (SCC) in situ by topical application. Although structurally related to p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88afc0905cbf7e0c5d46cb204c82922d
https://doi.org/10.1158/0008-5472.c.6500367
https://doi.org/10.1158/0008-5472.c.6500367
Autor:
Stuart H. Yuspa, Suresh V. Ambudkar, David J. Maloney, Susan H. Garfield, Andrew Lee, Suneet Shukla, Luowei Li
Supplementary Figures 1-5, Tables 1-2 from The Skin Cancer Chemotherapeutic Agent Ingenol-3-Angelate (PEP005) Is a Substrate for the Epidermal Multidrug Transporter (ABCB1) and Targets Tumor Vasculature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745bf1e60285075c3bbdea19895ac784
https://doi.org/10.1158/0008-5472.22382940.v1
https://doi.org/10.1158/0008-5472.22382940.v1
Autor:
William I. Smith, Asaf Raviv, Lalage M. Wakefield, Poonam Mannan, Langston Lim, Bao Tram Nghiem, Catherine Daniel, Ana I. Robles, Joshua Zimmerberg, Susan H. Garfield, Dominic Esposito, Kathleen C. Flanders, Rea Ravin, Binwu Tang
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 4, Iss 1, Pp 155-169 (2015)
Stem Cell Reports, Vol 4, Iss 1, Pp 155-169 (2015)
Summary Many tumors are hierarchically organized with a minority cell population that has stem-like properties and enhanced ability to initiate tumorigenesis and drive therapeutic relapse. These cancer stem cells (CSCs) are typically identified by co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8aee26a1e5a25769859966f106c719e
Autor:
Susan H. Garfield, Tamás Géczy, Poonam Mannan, Arnab Rudra, Madeleine Heldman, Langston Lim, Derek C. Braun, Thomas Cummins, Gary E. Keck, Julia S. Selezneva, Peter M. Blumberg, Nancy E. Lewin, Jin-Qiu Chen, Yam B. Poudel, Noemi Kedei, Michelle A. Herrmann
Publikováno v:
ACS Chemical Biology. 8:767-777
The bryostatins are a group of 20 macrolides isolated by Pettit and co-workers from the marine organism Bugula neritina. Bryostatin 1, the flagship member of the family, has been the subject of intense chemical and biological investigations due to it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eeb4025f89934e2f22b461478b5c5a5
https://doi.org/10.1021/cb300671s
https://doi.org/10.1021/cb300671s
Autor:
Hong-Wu Xin, Bo-Kyu Kim, Gordon W. Wiegand, Udo Rudloff, Alexander Stojadinovic, John E. Mullinax, Chenwi M. Ambe, Satyajit Ray, Itzhak Avital, Danielle M. Hari, Kshama R. Jaiswal, Snorri S. Thorgeirsson, Susan H. Garfield, Tomotake Koizumi
Publikováno v:
Journal of Cancer
Objective: Stem-like cancer cells contribute to cancer initiation and maintenance. Stem cells can self-renew by asymmetric cell division (ACD). ACD with non-random chromosomal cosegregation (ACD-NRCC) is one possible self-renewal mechanism. There is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ab4c222b93f3860bdb311bda2b221d
https://doi.org/10.7150/jca.6896
https://doi.org/10.7150/jca.6896
Autor:
Andrew J. Anderson, Snorri S. Thorgeirsson, Susan H. Garfield, Tomotake Koizumi, Gordon W. Wiegand, Itzhak Avital, Hong-Wu Xin, John E. Mullinax, Danielle M. Hari, Chenwi M. Ambe, Satyajit Ray
Publikováno v:
Stem Cells. 30:591-598
Label-retaining cells (LRCs) have been proposed to represent adult tissue stem cells. LRCs are hypothesized to result from either slow cycling or asymmetric cell division (ACD). However, the stem cell nature and whether LRC undergo ACD remain controv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e82089ab173a87e8722ff3151aa345
https://doi.org/10.1002/stem.1061
https://doi.org/10.1002/stem.1061
Autor:
A. Flugy, Elise C. Kohn, Giacomo De Leo, Riccardo Alessandro, Susan H. Garfield, Marco Mineo, Simona Taverna
Publikováno v:
Angiogenesis. 15:33-45
Exosomes, microvesicles of endocytic origin released by normal and tumor cells, play an important role in cell-to-cell communication. Angiogenesis has been shown to regulate progression of chronic myeloid leukemia (CML). The mechanism through which t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779875bc90f9f9d238b228bd77fd6d8f
https://doi.org/10.1007/s10456-011-9241-1
https://doi.org/10.1007/s10456-011-9241-1