First-Pass Meconium Samples from Healthy Term Vaginally-Delivered Neonates: An Analysis of the Microbiota.

Autor: Richard Hansen, Karen P Scott, Shoaib Khan, Jenny C Martin, Susan H Berry, Matthew Stevenson, Augusta Okpapi, Michael J Munro, Georgina L Hold

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0133320 (2015)

BackgroundConsiderable effort has been made to categorise the bacterial composition of the human gut and correlate findings with gastrointestinal disease. The infant gut has long been considered sterile at birth followed by rapid colonisation; howeve

Externí odkaz: https://doaj.org/article/8fe423a50a5a44d6965f954f6c9f55f6

The microaerophilic microbiota of de-novo paediatric inflammatory bowel disease: the BISCUIT study.

Autor: Richard Hansen, Susan H Berry, Indrani Mukhopadhya, John M Thomson, Karin A Saunders, Charlotte E Nicholl, W Michael Bisset, Sabarinathan Loganathan, Gamal Mahdi, Dagmar Kastner-Cole, Andy R Barclay, Jon Bishop, Diana M Flynn, Paraic McGrogan, Richard K Russell, Emad M El-Omar, Georgina L Hold

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e58825 (2013)

Children presenting for the first time with inflammatory bowel disease (IBD) offer a unique opportunity to study aetiological agents before the confounders of treatment. Microaerophilic bacteria can exploit the ecological niche of the intestinal epit

Externí odkaz: https://doaj.org/article/252176b8bfb34a519587f8ca47fbbe73

Detection of Campylobacter concisus and other Campylobacter species in colonic biopsies from adults with ulcerative colitis.

Autor: Indrani Mukhopadhya, John M Thomson, Richard Hansen, Susan H Berry, Emad M El-Omar, Georgina L Hold

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21490 (2011)

IntroductionThe critical role of bacteria in the pathogenesis of ulcerative colitis (UC) is well recognized, but an individual causative microorganism has not been singled out so far. Campylobacter concisus and other non-jejuni species of Campylobact

Externí odkaz: https://doaj.org/article/90ac94e2774f4e59b0f000dc6c740b52

Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an ‘Immune Cold’ Phenotype Associated with Poor Survival

Autor: Ross J. Porter, Graeme I. Murray, Sandra Hapca, Andrew Hay, Stephanie G. Craig, Matthew P. Humphries, Jacqueline A. James, Manuel Salto-Tellez, Daniel P. Brice, Susan H. Berry, Mairi H. McLean

Publikováno v: Cancers; Volume 15; Issue 6; Pages: 1865
Porter, R J, Murray, G I, Hapca, S, Hay, A, Craig, S G, Humphries, M P, James, J A, Salto-Tellez, M, Brice, D P, Berry, S H & McLean, M H 2023, ' Subcellular Epithelial HMGB1 Expression Is Associated with Colorectal Neoplastic Progression, Male Sex, Mismatch Repair Protein Expression, Lymph Node Positivity, and an ‘Immune Cold’ Phenotype Associated with Poor Survival ', Cancers, vol. 15, no. 6, 1865 . https://doi.org/10.3390/cancers15061865
Porter, R J, Murray, G I, Hapca, S, Hay, A, Craig, S G, Humphries, M P, James, J A, Salto-Tellez, M, Brice, D P, Berry, S H & McLean, M H 2023, ' Subcellular epithelial HMGB1 expression is associated with colorectal neoplastic progression, male sex, mismatch repair protein expression, lymph node positivity, and an 'immune cold' phenotype associated with poor survival ', Cancers, vol. 15, no. 6, 1865, pp. 1865 . https://doi.org/10.3390/cancers15061865

New treatment targets are needed for colorectal cancer (CRC). We define expression of High Mobility Group Box 1 (HMGB1) protein throughout colorectal neoplastic progression and examine the biological consequences of aberrant expression. HMGB1 is a ub

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26eef120374bc4eb411d6c937144162c

Comparative genomics and genome biology of Campylobacter showae

Autor: Georgina L. Hold, Wendy S. Garrett, Indrani Mukhopadhya, Monia Michaud, Hans Ove Nielsen, Mona Bajaj-Elliott, Curtis Huttenhower, Henrik Nielsen, William G. Miller, Susan H. Berry, Tiffany Hsu, Matthew Gemmell, Eric A. Franzosa, Richard Hansen

Publikováno v: Emerging Microbes & Infections
Hsu, T, Gemmell, M R, Franzosa, E A, Berry, S, Mukhopadhya, I, Hansen, R, Michaud, M, Nielsen, H, Miller, W G, Nielsen, H, Bajaj-Elliott, M, Huttenhower, C, Garrett, W S & Hold, G L 2019, ' Comparative genomics and genome biology of Campylobacter showae ', Emerging microbes & infections, vol. 8, no. 1, pp. 827-840 . https://doi.org/10.1080/22221751.2019.1622455

Campylobacter showae a bacterium historically linked to gingivitis and periodontitis, has recently been associated with inflammatory bowel disease and colorectal cancer. Our aim was to generate genome sequences for new clinical C. showae strains and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd7388dedcea6812ca04a3fefebb197
http://europepmc.org/articles/PMC6567213