Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Susan Glasco"'
Autor:
Lawrence D'Souza, Ramina Nazarbaghi, Uday Maitra, Nicholas J. Ede, Yazhong Pei, Walter H. Moos, Susan Glasco, Xiao-Qing Tang, Ian W. James, Srinivasan Chandrasekaran, Soumitra Ghosh, Andrew N. Hunter, David J. Owen, Michael J Lilly, Jinghua Yu, Christen M. Anderson
Publikováno v:
The Journal of Organic Chemistry. 68:92-103
Type II diabetes mellitus is a chronic metabolic disorder that can lead to serious cardiovascular, renal, neurologic, and retinal complications. While several drugs are currently prescribed to treat type II diabetes, their efficacy is limited by mech
Autor:
Philip D.G. Miles, Christen M. Anderson, Claes B. Wollheim, Leonardo Vargas, Kathryn A. Grako, Yulia Kushnareva, Susan Glasco, Pierre Maechler, Bumsup Lee, Elisabeth S. Kornbrust, Peng Luan, Jerrold M. Olefsky
Publikováno v:
Diabetes. 52(4)
The mitochondrial Na(+)-Ca(2+) exchanger (mNCE) mediates efflux of Ca(2+) from mitochondria in exchange for influx of Na(+). We show that inhibition of the mNCE enhances mitochondrial oxidative metabolism and increases glucose-stimulated insulin secr