Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Susan Foltin"'
Autor:
Molly Heft Neal, Andrew Birkeland, Apurva Bhangale, Jingyi Zhai, Aditi Kulkarni, Susan Foltin, Brittany Jewell, Megan Ludwig, Lisa Pinatti, Hui Jiang, Jonathan McHugh, Lawence Marentette, Erin McKean, J Brenner
Background: Sinonasal Undifferentiated Carcinoma (SNUC) is a rare and aggressive skull base tumor with poor survival and limited treatment options. To date, targeted sequencing studies have identified IDH2 and SMARCB1 as potential driver alterations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21519dd2ceab1a451d3dbeca5f84fd4d
https://doi.org/10.21203/rs.3.rs-115402/v1
https://doi.org/10.21203/rs.3.rs-115402/v1
Autor:
Sarah E. Smith, Scott J. Bowen, Scott A. Long, David Beidler, Marvin J. Meyers, Atli Thorarensen, Heather M. Madsen, Joseph J. McDonald, Susan Foltin, Barbara A. Schweitzer, Tenbrink Ruth E, Jane L. Wang, Mark C. Walker, Matthew James Pelc
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(21)
Herein we report the identification of two new fatty acid amide hydrolase (FAAH) inhibitor lead series with FAAH k(inact)/K(i) potency values greater than 1500M(-1)s(-1). The two novel spirocyclic cores, 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5
Autor:
Sarah E. Smith, Marvin J. Meyers, Young-Sun Yang, Joseph J. McDonald, David Beidler, Atli Thorarensen, Matthew James Pelc, Jeanne M. Rumsey, Mark V. Wilcox, Satwik Kamtekar, Scott A. Long, Scott J. Bowen, Jane L. Wang, Mark C. Walker, Susan Foltin, Barbara A. Schweitzer
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(21)
Fatty acid amide hydrolase (FAAH) is an integral membrane serine hydrolase responsible for the degradation of fatty acid amide signaling molecules such as endocannabinoid anandamide (AEA), which has been shown to possess cannabinoid-like analgesic pr