Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Susan Finniss"'
Autor:
Hae Kyung Lee, Ariel Bier, Simona Cazacu, Susan Finniss, Cunli Xiang, Hodaya Twito, Laila M Poisson, Tom Mikkelsen, Shimon Slavin, Elad Jacoby, Michal Yalon, Amos Toren, Sandra A Rempel, Chaya Brodie
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54652 (2013)
Glioblastomas (GBM), the most common and aggressive type of malignant glioma, are characterized by increased invasion into the surrounding brain tissues. Despite intensive therapeutic strategies, the median survival of GBM patients has remained disma
Externí odkaz:
https://doaj.org/article/5b4578dbd2514421a2e85381362b4f5c
Autor:
Hae Kyung Lee, Gila Kazimirsky, Susan Finniss, Rachela Popovtzer, Simona Cazacu, Gal Yadid, Menachem Motiei, Amit Shwartz, Shani Yael Dagan, Noam Kronfeld, Oshra Betzer, Chaya Brodie
Publikováno v:
Theranostics
Recent studies have proposed that abnormal glutamatergic neurotransmission and glial pathology play an important role in the etiology and manifestation of depression. It was postulated that restoration of normal glutamatergic transmission, by enhanci
Autor:
Laila M. Poisson, Hae Kyung Lee, Amotz Ziv-Av, Susan Finniss, Tom Mikkelsen, Cunli Xiang, Nis Giladi, Chaya Brodie, Ana C. deCarvalho, Hiba Waldman Ben-Asher, Simona Cazacu
Publikováno v:
Oncotarget
Glioblastomas (GBMs), the most aggressive primary brain tumors, exhibit increased invasiveness and resistance to anti-tumor treatments. We explored the role of RTVP-1, a glioma-associated protein that promotes glioma cell migration, in the mesenchyma
Autor:
Cunli Xiang, Mira Barda-Saad, Laila M. Poisson, Simona Cazacu, Nissim David Giladi, Maor H. Pauker, Hae Kyung Lee, Amotz Ziv-Av, Susan Finniss, Chaya Brodie
Publikováno v:
Oncotarget
Glioblastoma (GBM) are characterized by increased invasion into the surrounding normal brain tissue. RTVP-1 is highly expressed in GBM and regulates the migration and invasion of glioma cells. To further study RTVP-1 effects we performed a pull-down
Autor:
Laila M. Poisson, Susan Finniss, Simona Cazacu, Hae Kyung Lee, Cunli Xiang, Peter M. Blumberg, Chaya Brodie
Publikováno v:
Oncotarget
Glioblastoma (GBM), the most aggressive primary brain tumors, are highly infiltrative. Although GBM express high Ras activity and Ras proteins have been implicated in gliomagenesis, Ras-activating mutations are not frequent in these tumors. RasGRP3,
Publikováno v:
Stem Cells and Development. 23:2851-2861
MicroRNAs (miRNAs) are potential therapeutic targets in a variety of pathological conditions in the brain; however, their clinical application is hampered by lack of efficient delivery modes. Mesenchymal stromal stem cells (MSCs) migrate to sites of
Autor:
Kevin R. Bobbitt, Cunli Xiang, Hae Kyung Lee, Simona Cazacu, Susan Finniss, Sandra A. Rempel, Laura Hasselbach, Shimon Slavin, Efrat Bucris, Amotz Ziv-Av, Tom Mikkelsen, Chaya Brodie
Publikováno v:
Oncotarget
// Hae Kyung Lee 1 , Susan Finniss 1 , Simona Cazacu 1 , Efrat Bucris 2 , Amotz Ziv-Av 2 , Cunli Xiang 1 , Kevin Bobbitt 3 , Sandra A. Rempel 4 , Laura Hasselbach 5 , Tom Mikkelsen 5 Shimon Slavin 6 and Chaya Brodie 1,2 1 Davidson Laboratory of Cell
Autor:
Laila M. Poisson, Cunli Xiang, Tom Mikkelsen, Simona Cazacu, Chaya Brodie, Ziv Brodie, Susan Finniss, David B. Shackelford, Wei Jiang
Publikováno v:
Oncotarget
// Wei Jiang, 1 Susan Finniss, 1 Simona Cazacu, 1 Cunli Xiang, 1 Ziv Brodie, 1 Tom Mikkelsen 1 , Laila Poisson 2 , David B. Shackelford 3 , Chaya Brodie 1, 4 1 Davidson Laboratory of Cell Signaling and Tumorigenesis, Hermelin Brain Tumor Center, Depa
Autor:
Sarit Kahana, Tom Mikkelsen, Cunli Xiang, Simona Cazacu, Shlomit Brodie, Shimon Slavin, Vered Roitman, Susan Finniss, Hae Kyung Lee, Ronald S. Goldstein, Chaya Brodie
Publikováno v:
Cellular Signalling. 23:1348-1357
In this study we examined the effects of proteasome inhibitors on cell apoptosis in TRAIL-resistant glioma cells and glioma stem cells (GSCs). Treatment with proteasome inhibitors and TRAIL induced apoptosis in all the resistant glioma cells and GSCs
Autor:
Cunli Xiang, Sandra A. Rempel, Tom Mikkelsen, Stephanie L. Lomonaco, Wei Jiang, Chaya Brodie, Nancy Lemke, Susan Finniss, Hae Kyung Lee
Publikováno v:
Neuro-Oncology. 13:857-865
We studied the effect of the integrin inhibitor cilengitide in glioma cells. Cilengitide induced cell detachment and decreased cell viability, and induction of autophagy followed by cell apoptosis. In addition, cilengitide decreased the cell renewal