Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Susan Finniss"'
Autor:
Hae Kyung Lee, Ariel Bier, Simona Cazacu, Susan Finniss, Cunli Xiang, Hodaya Twito, Laila M Poisson, Tom Mikkelsen, Shimon Slavin, Elad Jacoby, Michal Yalon, Amos Toren, Sandra A Rempel, Chaya Brodie
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54652 (2013)
Glioblastomas (GBM), the most common and aggressive type of malignant glioma, are characterized by increased invasion into the surrounding brain tissues. Despite intensive therapeutic strategies, the median survival of GBM patients has remained disma
Externí odkaz:
https://doaj.org/article/5b4578dbd2514421a2e85381362b4f5c
Autor:
Hae Kyung Lee, Gila Kazimirsky, Susan Finniss, Rachela Popovtzer, Simona Cazacu, Gal Yadid, Menachem Motiei, Amit Shwartz, Shani Yael Dagan, Noam Kronfeld, Oshra Betzer, Chaya Brodie
Publikováno v:
Theranostics
Recent studies have proposed that abnormal glutamatergic neurotransmission and glial pathology play an important role in the etiology and manifestation of depression. It was postulated that restoration of normal glutamatergic transmission, by enhanci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99aeaf146b77c0fca91d7dc4da2d27a5
https://doi.org/10.7150/thno.18914
https://doi.org/10.7150/thno.18914
Autor:
Laila M. Poisson, Hae Kyung Lee, Amotz Ziv-Av, Susan Finniss, Tom Mikkelsen, Cunli Xiang, Nis Giladi, Chaya Brodie, Ana C. deCarvalho, Hiba Waldman Ben-Asher, Simona Cazacu
Publikováno v:
Oncotarget
Glioblastomas (GBMs), the most aggressive primary brain tumors, exhibit increased invasiveness and resistance to anti-tumor treatments. We explored the role of RTVP-1, a glioma-associated protein that promotes glioma cell migration, in the mesenchyma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c5aeb8a564964eff294689e3bed44e
https://doi.org/10.18632/oncotarget.4205
https://doi.org/10.18632/oncotarget.4205
Autor:
Kevin R. Bobbitt, Cunli Xiang, Hae Kyung Lee, Simona Cazacu, Susan Finniss, Sandra A. Rempel, Laura Hasselbach, Shimon Slavin, Efrat Bucris, Amotz Ziv-Av, Tom Mikkelsen, Chaya Brodie
Publikováno v:
Oncotarget
// Hae Kyung Lee 1 , Susan Finniss 1 , Simona Cazacu 1 , Efrat Bucris 2 , Amotz Ziv-Av 2 , Cunli Xiang 1 , Kevin Bobbitt 3 , Sandra A. Rempel 4 , Laura Hasselbach 5 , Tom Mikkelsen 5 Shimon Slavin 6 and Chaya Brodie 1,2 1 Davidson Laboratory of Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65fa64bd725639fd9042bad7e984103c
http://europepmc.org/articles/PMC3712579
http://europepmc.org/articles/PMC3712579
Autor:
Cunli Xiang, Mira Barda-Saad, Laila M. Poisson, Simona Cazacu, Nissim David Giladi, Maor H. Pauker, Hae Kyung Lee, Amotz Ziv-Av, Susan Finniss, Chaya Brodie
Publikováno v:
Oncotarget
Glioblastoma (GBM) are characterized by increased invasion into the surrounding normal brain tissue. RTVP-1 is highly expressed in GBM and regulates the migration and invasion of glioma cells. To further study RTVP-1 effects we performed a pull-down
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2b105e3fa948889f8ef4082e6bf1f7b
https://doi.org/10.18632/oncotarget.4471
https://doi.org/10.18632/oncotarget.4471
Autor:
Laila M. Poisson, Susan Finniss, Simona Cazacu, Hae Kyung Lee, Cunli Xiang, Peter M. Blumberg, Chaya Brodie
Publikováno v:
Oncotarget
Glioblastoma (GBM), the most aggressive primary brain tumors, are highly infiltrative. Although GBM express high Ras activity and Ras proteins have been implicated in gliomagenesis, Ras-activating mutations are not frequent in these tumors. RasGRP3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e616d08d86c76edfeb35f00bd8313a
https://doi.org/10.18632/oncotarget.2575
https://doi.org/10.18632/oncotarget.2575
Autor:
Laila M. Poisson, Cunli Xiang, Tom Mikkelsen, Simona Cazacu, Chaya Brodie, Ziv Brodie, Susan Finniss, David B. Shackelford, Wei Jiang
Publikováno v:
Oncotarget
// Wei Jiang, 1 Susan Finniss, 1 Simona Cazacu, 1 Cunli Xiang, 1 Ziv Brodie, 1 Tom Mikkelsen 1 , Laila Poisson 2 , David B. Shackelford 3 , Chaya Brodie 1, 4 1 Davidson Laboratory of Cell Signaling and Tumorigenesis, Hermelin Brain Tumor Center, Depa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf54bb055c692040829114ff9d2d2340
https://pubmed.ncbi.nlm.nih.gov/27486821
https://pubmed.ncbi.nlm.nih.gov/27486821
Publikováno v:
Stem Cells and Development. 23:2851-2861
MicroRNAs (miRNAs) are potential therapeutic targets in a variety of pathological conditions in the brain; however, their clinical application is hampered by lack of efficient delivery modes. Mesenchymal stromal stem cells (MSCs) migrate to sites of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b53b54e5c7ffd7e7e84592c56cd2f78
https://doi.org/10.1089/scd.2014.0146
https://doi.org/10.1089/scd.2014.0146
Autor:
Sarit Kahana, Tom Mikkelsen, Cunli Xiang, Simona Cazacu, Shlomit Brodie, Shimon Slavin, Vered Roitman, Susan Finniss, Hae Kyung Lee, Ronald S. Goldstein, Chaya Brodie
Publikováno v:
Cellular Signalling. 23:1348-1357
In this study we examined the effects of proteasome inhibitors on cell apoptosis in TRAIL-resistant glioma cells and glioma stem cells (GSCs). Treatment with proteasome inhibitors and TRAIL induced apoptosis in all the resistant glioma cells and GSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6f88b62e02d4ae20c7b9eb48b2f539
https://doi.org/10.1016/j.cellsig.2011.03.017
https://doi.org/10.1016/j.cellsig.2011.03.017
Autor:
Cunli Xiang, Sandra A. Rempel, Tom Mikkelsen, Stephanie L. Lomonaco, Wei Jiang, Chaya Brodie, Nancy Lemke, Susan Finniss, Hae Kyung Lee
Publikováno v:
Neuro-Oncology. 13:857-865
We studied the effect of the integrin inhibitor cilengitide in glioma cells. Cilengitide induced cell detachment and decreased cell viability, and induction of autophagy followed by cell apoptosis. In addition, cilengitide decreased the cell renewal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239bf6c9d782447d0f897de81557df11
https://doi.org/10.1093/neuonc/nor073
https://doi.org/10.1093/neuonc/nor073