Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan Eliazer"'
Publikováno v:
eLife, Vol 11 (2022)
The quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remains unkn
Externí odkaz:
https://doaj.org/article/6161cb6243494aedb6f5e9b29e658b79
Autor:
Nevine A. Shalaby, Raheel Sayed, Qiao Zhang, Shane Scoggin, Susan Eliazer, Adrian Rothenfluh, Michael Buszczak
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Jumonji (JmjC) domain proteins influence gene expression and chromatin organization by way of histone demethylation, which provides a means to regulate the activity of genes across the genome. JmjC proteins have been associated with many hum
Externí odkaz:
https://doaj.org/article/47ad0110818946e8ae66ce69c73acfe1
Autor:
Susan Eliazer, Victor Palacios, Zhaohui Wang, Rahul K Kollipara, Ralf Kittler, Michael Buszczak
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004200 (2014)
Specialized microenvironments called niches regulate tissue homeostasis by controlling the balance between stem cell self-renewal and the differentiation of stem cell daughters. However the mechanisms that govern the formation, size and signaling of
Externí odkaz:
https://doaj.org/article/bd29e973622a4faa83e36fa4cb762411
Publikováno v:
eLife. 11
The quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remains unkn
SummaryThe quiescent muscle stem cell (QSC) pool is heterogeneous and generally characterized by the presence and levels of intrinsic myogenic transcription factors. Whether extrinsic factors maintain the diversity of states across the QSC pool remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7337d6ba9dfddb978745ce63fe68b6fa
https://doi.org/10.1101/2020.10.20.347484
https://doi.org/10.1101/2020.10.20.347484
Autor:
Susan Eliazer, Qiao Zhang, Michael Buszczak, Raheel Sayed, Nevine A. Shalaby, Adrian Rothenfluh, Shane Scoggin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Jumonji (JmjC) domain proteins influence gene expression and chromatin organization by way of histone demethylation, which provides a means to regulate the activity of genes across the genome. JmjC proteins have been associated with many human diseas
Autor:
Xuefeng Sun, Rebecca S. D’Urso, Jonathon M. Muncie, Valerie M. Weaver, Andrew S. Brack, Josef Christensen, Susan Eliazer
Publikováno v:
Cell Stem Cell
Cell stem cell, vol 25, iss 5
Cell stem cell, vol 25, iss 5
Summary Satellite cells (SCs) reside in a dormant state during tissue homeostasis. The specific paracrine agents and niche cells that maintain SC quiescence remain unknown. We find that Wnt4 produced by the muscle fiber maintains SC quiescence throug
Autor:
Susan Eliazer, Andrew S. Brack
Publikováno v:
Cell Stem Cell. 18(1):5-7
Quiescence is highly regulated to preserve stem cell function. In this issue of Cell Stem Cell, Zismanov et al. (2016) show that P-eIF2α, a translational initiation factor, reinforces the quiescent state of muscle stem cells by safeguarding against
The mechanisms that modulate and limit the signaling output of adult stem cell niches remain poorly understood. To gain further insights into how these microenvironments are regulated in vivo, we performed a candidate gene screen designed to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e57fa3bcd565da41105de0708d8789
https://europepmc.org/articles/PMC5001506/
https://europepmc.org/articles/PMC5001506/