Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Susan E.M. Clarke"'
1
A Novel Activating Mutation in the RET Tyrosine Kinase Domain Mediates Neoplastic Transformation
Autor: Marco A. Pierotti, Italia Bongarzone, Cristiana Carniti, Aaron N. Cranston, Bruce A.J. Ponder, Susan E.M. Clarke, Yvette Hooks, Shirley Hodgson, Jean Leyland, Piera Mondellini, Sam Martin
Publikováno v: Molecular Endocrinology. 20:1633-1643
We report the finding of a novel missense mutation at codon 833 in the tyrosine kinase of the RET proto-oncogene in a patient with a carcinoma of the thyroid. In vitro experiments demonstrate that the R833C mutation induces transformed foci only when
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512461396d6060e8e9d481b797894ad1
https://doi.org/10.1210/me.2004-0447
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2
Real-Time Quantitative PCR Measurement of Thyroglobulin mRNA in Peripheral Blood of Thyroid Cancer Patients and Healthy Subjects
Autor: Ramasamyiyer Swaminathan, Susan E.M. Clarke, Asif N. Butt, Diane Li
Publikováno v: Annals of the New York Academy of Sciences. 1022:147-151
Follow-up of recurrent differentiated thyroid carcinoma involves the measurement of serum thyroglobulin (Tg). However, Tg autoantibodies are present in a high proportion of thyroid carcinoma patients (up to 25%) and these can interfere with the Tg im
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2be59410c7d9d8548d4b083b38d38eb
https://doi.org/10.1196/annals.1318.024
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3
Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin gene
Autor: Clive Harmer, Sanjay Popat, Tania Kantemiroff, William D. Foulkes, Susan E.M. Clarke, Richard S. Houlston, Athena Matakidou, Nancy Hamel, Kiersten A. Henderson
Publikováno v: Carcinogenesis. 25:369-373
Benign thyroid disorders are strong risk factors for nonmedullary thyroid cancer (NMTC). Germline variation in Tg (thyroglobulin) and TSHR (thyroid stimulating hormone receptor) confers an increased risk of benign thyroid disorders. To explore the hy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d4c53cf0214a0b97865f9ef28b7e74
https://doi.org/10.1093/carcin/bgh027
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5
Isotopic evaluation and therapy in patients with malignant endocrine disease
Autor: Susan E.M. Clarke, Val Lewington
Publikováno v: Best Practice & Research Clinical Endocrinology & Metabolism. 15:225-239
The contribution of nuclear medicine to the diagnosis and treatment of endocrine malignancy is increasing. Advances in molecular biology offer new opportunities for tumour targeting via surface receptor recognition and tumour-specific metabolic marke
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d3af03d60227148be269aed2883151
https://doi.org/10.1053/beem.2001.0137
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6
Technetium-99m tetrofosmin myocardial perfusion scan: comparison of 1-day and 2-day protocols
Autor: Ignac Fogelman, Susan E.M. Clarke, John C. Chambers, Michael N. Maisey, T K Yong
Publikováno v: European Journal of Nuclear Medicine. 23:320-325
Nineteen patients with angina were recruited in this study for comparison of two 1-day protocols (stress-4h rest and rest-4-h stress) and a 2-day protocol of technetium-99m tetrofosmin single-photon emission tomography (SPET). All of them underwent c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee63946fe552e63fe60b86dfe8a9d05
https://doi.org/10.1007/bf00837631
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7
The SNMMI practice guideline for therapy of thyroid disease with 131I 3.0
Autor: Chaitanya R. Divgi, Edward B. Silberstein, Abass Alavi, Henry D. Royal, Michael J. Gelfand, Susan E.M. Clarke, Helena Balon, Alan D. Waxman, William H. Martin, Stanley J. Goldsmith, Hossein Jadvar, Michael G. Stabin, Carol S. Marcus, Salil D. Sarkar, J. Anthony Parker
Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 53(10)
Preamble……1 I. Introduction: patient management, licensure.……2 II. Goals.……2 III. Definitions: risk levels……2 IV. Common clinical indications……3 V. Qualifications and responsibilities of personnel (in the United States).……3 VI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c955651baf16b7c0a509384c222e349
https://pubmed.ncbi.nlm.nih.gov/23287579
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8
Metastatic squamous carcinoma in the neck: an anatomical and physiological study using CT and SPECT99Tcm(V) DMSA
Autor: J. C. Watkinson, Susan E.M. Clarke, C. E. C. Todd, Colin R. Lazarus, Michael N. Maisey
Publikováno v: The British Journal of Radiology. 64:909-914
Technetium-99m (99Tcm)(V) dimercaptosuccinic acid (DMSA) is a new tumour imaging agent that has been used to image squamous cell carcinoma (SCC) of the head and neck. This study has been undertaken to compare clinical examination with computed tomogr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722e88f910de93438beaf0ad75ad24f0
https://doi.org/10.1259/0007-1285-64-766-909
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10
Thyroid hormone and parathyroid hormone competing to maintain calcium levels in the presence of vitamin D deficiency
Autor: Ashley M. Groves, Hosahalli Mohan, Susan E.M. Clarke, Ignac Fogelman
Publikováno v: Thyroid : official journal of the American Thyroid Association. 14(9)
Weight loss and bone disease in the elderly are very often attributed to malignancy. Rarely, benign treatable conditions may be overlooked. Thyrotoxicosis, a benign treatable condition, needs to be excluded in such patients. The diagnosis may be dela
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86fb410d17cf44e2629602f5d37970d
https://pubmed.ncbi.nlm.nih.gov/15361268
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