Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Susan E. Zimmerman"'
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 5 (2020)
While genomic instability and mitochondrial homeostasis are integral for cancer progression, how these two hallmarks interact remains poorly understood. Here, we reflect on the dialogue between chromatin-based genomic instability and impairment of mi
Externí odkaz:
https://doaj.org/article/7d70f0fdd08a4ad5afbccc72b2aedd57
Publikováno v:
International review of cell and molecular biology. 364
Genomic instability and metabolic reprogramming are among the key hallmarks discriminating cancer cells from normal cells. The two phenomena contribute to the robust and evasive nature of cancer, particularly when cancer cells are exposed to chemothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bfdc8a4f2136486601975c54727be50a
https://pubmed.ncbi.nlm.nih.gov/34507785
https://pubmed.ncbi.nlm.nih.gov/34507785
Publikováno v:
Chromatin and Genomic Instability in Cancer ISBN: 9780323855617
Genomic instability and metabolic reprogramming are among the key hallmarks discriminating cancer cells from normal cells. The two phenomena contribute to the robust and evasive nature of cancer, particularly when cancer cells are exposed to chemothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37efda8c8ad872d613cd4308e47c237f
https://doi.org/10.1016/bs.ircmb.2021.05.004
https://doi.org/10.1016/bs.ircmb.2021.05.004
Autor:
Zhufeng Yang, Chitkale Hiremath, Denise K. Marciano, Jun Tsunezumi, Bronwyn Finney, Susan E. Zimmerman
Publikováno v:
Journal of the American Society of Nephrology. 29:1128-1140
A critical aspect of kidney function occurs at the glomerulus, the capillary network that filters the blood. The glomerular basement membrane (GBM) is a key component of filtration, yet our understanding of GBM interactions with mesangial cells, spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6872f1abdb8f76489cc8b73fb79198c7
https://doi.org/10.1681/asn.2017070752
https://doi.org/10.1681/asn.2017070752
Autor:
David M. Bryant, Consuelo González-Manchón, Jun Tsunezumi, Susan E. Zimmerman, Zhufeng Yang, Cary Trent, Caitlin M. Braitsch, Ondine Cleaver, Denise K. Marciano
Publikováno v:
Developmental Biology. 418:66-74
Previous studies have shown CD34 family member Podocalyxin is required for epithelial lumen formation in vitro. We demonstrate that Endoglycan, a CD34 family member with homology to Podocalyxin, is produced prior to lumen formation in developing neph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef3fcc62d03930fec09258bade75dc0
https://doi.org/10.1016/j.ydbio.2016.08.009
https://doi.org/10.1016/j.ydbio.2016.08.009
Autor:
Nicolas G. Bazan, Jili Zhu, Richard J. Quigg, Xin J. Zhou, Moumita Chaki, Dongmei Lu, Bokkyoo Jun, Susan E. Zimmerman, Alysha Rauhauser, Chandra Mohan, Sarah Elhadi, Komal Vadnagara, Shan Shan Wang, Chongyu Ren, Binghua Li, Denise K. Marciano, Fatih Ozaltin, Matthew K. Topham, Massimo Attanasio, Hanquin Wang, Yong Du
Publikováno v:
American Journal of Physiology-Renal Physiology. 310:F895-F908
Thrombotic microangiopathy (TMA) is a disorder characterized by microvascular occlusion that can lead to thrombocytopenia, hemolytic anemia, and glomerular damage. Complement activation is the central event in most cases of TMA. Primary forms of TMA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b93f563bf47c33c9483e7988ebb519
https://doi.org/10.1152/ajprenal.00431.2015
https://doi.org/10.1152/ajprenal.00431.2015
Autor:
Lei, Gao, Zhufeng, Yang, Chitkale, Hiremath, Susan E, Zimmerman, Blake, Long, Paul R, Brakeman, Keith E, Mostov, David M, Bryant, Katherine, Luby-Phelps, Denise K, Marciano
Publikováno v:
Development (Cambridge, England). 144(19)
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found that the F-actin-binding protein afadin is required for lumen continuity in developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d64ef9f58095dfb3ae804d6cc682862
https://pubmed.ncbi.nlm.nih.gov/28860115
https://pubmed.ncbi.nlm.nih.gov/28860115
Autor:
Chitkale Hiremath, Paul Brakeman, Zhufeng Yang, Lei Gao, Keith E. Mostov, David M. Bryant, Denise K. Marciano, Susan E. Zimmerman, Blake Long, Katherine Luby-Phelps
Publikováno v:
Development.
In many types of tubules, continuity of the lumen is paramount to tubular function, yet how tubules generate lumen continuity in vivo is not known. We recently found that the F-actin-binding protein afadin is required for lumen continuity in developi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::892f07958a00e21cf8312f8670157499
https://doi.org/10.1242/dev.148908
https://doi.org/10.1242/dev.148908
Publikováno v:
International Journal of Migration, Health and Social Care. 8:180-185
PurposeAs immigration detainee numbers grow, doubts have arisen over the consistency, quality and suitability of the health care services provided among the UK detention estate and in other Western countries. Detained immigrants, due to their past an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8cc1357f221331e9aec21e46f61820
https://doi.org/10.1108/17479891211287094
https://doi.org/10.1108/17479891211287094
Autor:
Denise K. Marciano, Zhufeng Yang, Susan E. Zimmerman, Gerard M.J. Beaudoin, Paul Brakeman, Louis F. Reichardt
Publikováno v:
Development (Cambridge, England), vol 140, iss 8
Yang, Z; Zimmerman, S; Brakeman, PR; Beaudoin, GM; Reichardt, LF; & Marciano, DK. (2013). De novo lumen formation and elongation in the developing nephron: A central role for afadin in apical polarity. Development (Cambridge), 140(8), 1774-1784. doi: 10.1242/dev.087957. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5kj5k9px
Yang, Z; Zimmerman, S; Brakeman, PR; Beaudoin, GM; Reichardt, LF; & Marciano, DK. (2013). De novo lumen formation and elongation in the developing nephron: A central role for afadin in apical polarity. Development (Cambridge), 140(8), 1774-1784. doi: 10.1242/dev.087957. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5kj5k9px
A fundamental process in biology is the de novo formation and morphogenesis of polarized tubules. Although these processes are essential for the formation of multiple metazoan organ systems, little is known about the molecular mechanisms that regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37389d82c87a8252d584cacb3c732ebf
https://escholarship.org/uc/item/5kj5k9px
https://escholarship.org/uc/item/5kj5k9px