Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Susan E. Rutberg"'
Autor:
Douglas Shander, Gege Tan, Susan E. Rutberg, Meredith L. Kolpak, Henry James P, John A. Gourley
Publikováno v:
Journal of Investigative Dermatology. 126(12):2583-2595
Androgen exposure stimulates the growth of beard hair follicles. The follicle dermal papilla appears to be the site of androgen action; however, the molecular mechanisms that regulate this process are not well understood. In an attempt to identify ge
Autor:
Enrique Saez, Sam Lo, Susan E. Rutberg, Stuart H. Yuspa, Nedialka Markova, Shyh-Ing Jang, Bruce M. Spiegelman
Publikováno v:
Oncogene. 15:1337-1346
The major differentiation products of maturing keratinocytes contain AP-1 regulatory motifs, and AP-1 DNA binding activity increases in cultured keratinocytes induced to differentiate by calcium. Here, we have analysed AP-1 transcriptional activity i
Publikováno v:
Molecular Carcinogenesis. 20:88-98
Previous studies have demonstrated a role for the fos gene in promoting malignant conversion of mouse skin tumors. In the study reported here, differential display was performed to identify fos- and jun-regulated genes that are differentially express
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1261:90-98
Mouse fibroblast cells (WOP) express permissive factors which support polyoma DNA replication. However, electroporation into WOP cells of a mammalian expression vector that encodes the c-jun cDNA results in repression of polyoma DNA replication in a
Publikováno v:
DNA and Cell Biology. 13:865-874
Previously, we have shown that integrated copies of polyoma DNA can be induced to replicate in rat fibroblasts (H3 cells) exposed to a DNA-damaging agent. In the current study, we demonstrate that UV-irradiation of mouse fibroblasts (WOP cells), tran
Publikováno v:
Molecular Carcinogenesis. 10:82-87
The expression and DNA binding activity of members of the activating protein-1 (AP-1) and activating transcription factor (ATF) families of transcription factors were analyzed in sham and ultraviolet (UV)-irradiated subclones of the B16 mouse melanom
Publikováno v:
Oncogene. 18(8)
Previously, we have shown that nuclear extracts from cultured mouse keratinocytes induced to differentiate by increasing the levels of extra-cellular calcium contain Fra-1, Fra-2, Jun B, Jun D and c-Jun proteins that bind to the AP-1 DNA binding sequ
Autor:
Christina Cheng, Andrzej A. Dlugosz, Mitchell F. Denning, Susan E. Rutberg, Stuart H. Yuspa, Caroline Stanwell
Publikováno v:
The Journal of investigative dermatology. 106(3)
Staurosporine (stsp) induces assembly of cornified envelopes in mouse keratinocyte cultures. To clarify whether this effect is the consequence of a coordinated differentiation program similar to that observed in epidermis, we assessed the expression
Autor:
Jennifer Smoluk, Enrique Saez, Stuart H. Yuspa, Bruce M. Spiegelman, Heather Oppenheim, Susan E. Rutberg, Elisabetta Mueller
Publikováno v:
Cell. 82(5)
The proto-oncogene c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using the multistep skin carcinogenesis model, we have directly tested the ability of
Autor:
Susan E. Rutberg, Ze'ev Ronai
Publikováno v:
Photochemistry and photobiology. 58(2)
— We have previously demonstrated the ability of UVC (254 nm) radiation to induce asynchronous polyoma replication in rat fibroblast cells (H3 line) that contain an integrated copy of polyoma virus. In the present study we show that general purpose