Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Susan E. Ptak"'
Autor:
Anne Fischer, Kay Prüfer, Jeffrey M Good, Michel Halbwax, Victor Wiebe, Claudine André, Rebeca Atencia, Lawrence Mugisha, Susan E Ptak, Svante Pääbo
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21605 (2011)
To gain insight into the patterns of genetic variation and evolutionary relationships within and between bonobos and chimpanzees, we sequenced 150,000 base pairs of nuclear DNA divided among 15 autosomal regions as well as the complete mitochondrial
Externí odkaz:
https://doaj.org/article/7f308bc2258a4ed39a67b6c7bab74dac
Publikováno v:
PLoS Biology, Vol 2, Iss 6, p e155 (2004)
Recent experiments using sperm typing have demonstrated that, in several regions of the human genome, recombination does not occur uniformly but instead is concentrated in "hotspots" of 1-2 kb. Moreover, the crossover asymmetry observed in a subset o
Externí odkaz:
https://doaj.org/article/cb2e1398d2a047b3ad3184b61e4c6d67
Autor:
Svante Pääbo, Susan E. Ptak, Michael Lachmann, Johannes Krause, Victor Wiebe, Wolfgang Enard, Ines Hellmann
Publikováno v:
Molecular Biology and Evolution
Polymorphism data in humans suggest that the gene encoding the transcription factor FOXP2, which influences speech and language development, has been subject to a selective sweep within the last 260,000 years. It has been proposed that one or both of
Autor:
Norman Arnheim, Yudong Qian, Vanessa J. Clark, Anna Di Rienzo, Irene Tiemann, Susan E. Ptak, Graham Coop, Molly Przeworski, Anne C. Stone
Publikováno v:
Genetics. 175:795-804
A previous polymorphism survey of the type 2 diabetes gene CAPN10 identified a segment showing an excess of polymorphism levels in all population samples, coinciding with localized breakdown of linkage disequilibrium (LD) in a sample of Hausa from Ca
Publikováno v:
Genetics. 167:387-397
An ability to predict levels of linkage disequilibrium (LD) between linked markers would facilitate the design of association studies and help to distinguish between evolutionary models. Unfortunately, levels of LD depend crucially on the rate of rec
Autor:
Michael Lachmann, Susan E. Ptak
Publikováno v:
Behavioral Ecology. 14(2):201-211
The polygyny threshold model states that if costs incurred are less than the benefits gained from mating polygynously in terms of breeding-situation quality, then polygyny is favored and could evolve. We constructed mathematical models and computer s
Autor:
Nick Patterson, Mario Ventura, Roger Winer, Brian P. Walenz, Michael Lachmann, Lawrence Mugisha, Claudia Rita Catacchio, Asger Hobolth, Kasper Munch, Gerton Lunter, Saneyuki Higashino, Anne Fischer, Chris P. Ponting, Thomas Mailund, Can Alkan, Jörg Junhold, Jason R. Miller, Svante Pääbo, James C. Mullikin, Kay Prüfer, Emre Karakoc, Mikkel H. Schierup, Keiko Akagi, Tomas Marques-Bonet, Granger G. Sutton, Claudine André, Susan E. Ptak, Rebeca Atencia, Stephen Meader, Jeffrey M. Good, Michael Siebauer, Ines Hellmann, James R. Knight, Aida M. Andrés, Sergey Koren, David E. Symer, Chinnappa D. Kodira, Evan E. Eichler, Saba Sajjadian, Julien Y. Dutheil, Janet Kelso
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature
Prüfer, K, Munch, K, Hellmann, I, Akagi, K, Miller, J R, Walenz, B, Koren, S, Sutton, G, Kodira, C, Winer, R, Knight, J R, Mullikin, J C, Meader, S J, Ponting, C P, Lunter, G, Higashino, S, Hobolth, A, Dutheil, J, Karakoç, E, Alkan, C, Sajjadian, S, Catacchio, C R, Ventura, M, Marques-Bonet, T, Eichler, E E, André, C, Atencia, R, Mugisha, L, Junhold, J, Patterson, N, Siebauer, M, Good, J M, Fischer, A, Ptak, S E, Lachmann, M, Symer, D E, Mailund, T, Schierup, M H, Andrés, A M, Kelso, J & Pääbo, S 2012, ' The bonobo genome compared with the chimpanzee and human genomes ', Nature, vol. 486, no. 7404, pp. 527-31 . https://doi.org/10.1038/nature11128
instname
Nature
Prüfer, K, Munch, K, Hellmann, I, Akagi, K, Miller, J R, Walenz, B, Koren, S, Sutton, G, Kodira, C, Winer, R, Knight, J R, Mullikin, J C, Meader, S J, Ponting, C P, Lunter, G, Higashino, S, Hobolth, A, Dutheil, J, Karakoç, E, Alkan, C, Sajjadian, S, Catacchio, C R, Ventura, M, Marques-Bonet, T, Eichler, E E, André, C, Atencia, R, Mugisha, L, Junhold, J, Patterson, N, Siebauer, M, Good, J M, Fischer, A, Ptak, S E, Lachmann, M, Symer, D E, Mailund, T, Schierup, M H, Andrés, A M, Kelso, J & Pääbo, S 2012, ' The bonobo genome compared with the chimpanzee and human genomes ', Nature, vol. 486, no. 7404, pp. 527-31 . https://doi.org/10.1038/nature11128
Prüfer, K. et al.-- This article is distributed under the terms of the Creative Commons Attribution-Non-Commercial-Share Alike licence
Two African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo
Two African apes are the closest living relatives of humans: the chimpanzee (Pan troglodytes) and the bonobo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80a10a68dffc710944042daeff70180
http://hdl.handle.net/10261/80794
http://hdl.handle.net/10261/80794
Autor:
Michael T. Ronan, Jonathan M. Rothberg, Susan E. Ptak, Johannes Krause, Lei Du, Adrian W. Briggs, Jan Fredrik Simons, Maja Paunović, Michael Egholm, Richard E. Green, Svante Pääbo
Publikováno v:
Nature. 444(7117)
Neanderthals are the extinct hominid group most closely related to contemporary humans, so their genome offers a unique opportunity to identify genetic changes specific to anatomically fully modern humans. We have identified a 38,000-year-old Neander
Publikováno v:
Genome Research
Levels of diversity vary across the human genome. This variation is caused by two forces: differences in mutation rates and the differential impact of natural selection. Pertinent to the question of the relative importance of these two forces is the
Autor:
Nila Patil, Dennis G. Ballinger, Susan E. Ptak, Kathrin Koehler, Molly Przeworski, Birgit Nickel, Kelly A. Frazer, Svante Pääbo, David A. Hinds
Publikováno v:
Nature genetics. 37(4)
Recombination rates seem to vary extensively along the human genome. Pedigree analysis suggests that rates vary by an order of magnitude when measured at the megabase scale 1 , and at a finer scale, sperm typing studies point to the existence of reco