Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Susan E. McClory"'
1
Akademický článek
The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state, and its deletion improves checkpoint blockade
Autor: Susan E. McClory, Oishi Bardhan, Kelly S. Rome, Josephine R. Giles, Amy E. Baxter, Lanwei Xu, Phyllis A. Gimotty, Robert B. Faryabi, E. John Wherry, Warren S. Pear, Martha S. Jordan
Publikováno v: Cell Reports, Vol 42, Iss 8, Pp 112905- (2023)
Summary: CD8+ T cell exhaustion (TEX) impairs the ability of T cells to clear chronic infection or cancer. While TEX are hypofunctional, some TEX retain effector gene signatures, a feature associated with killer lectin-like receptor (KLR) expression.
Externí odkaz: https://doaj.org/article/649d5307b00c4acca7e424a01f75bf3e
Zobrazit plný text záznamu
2
The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR (+) CD8 (+) effector state and its deletion improves checkpoint blockade
Autor: Susan E. McClory, Oishi Bardhan, Kelly S. Rome, Josephine R. Giles, Amy E. Baxter, Lanwei Xu, Phyllis A. Gimotty, Robert B. Faryabi, E. John Wherry, Warren S. Pear, Martha S. Jordan
Publikováno v: bioRxiv
T cell exhaustion (TEX) impairs the ability of T cells to clear chronic infection or cancer. While exhausted T cells are hypofunctional, some exhausted T cells retain effector gene signatures, a feature that is associated with expression of KLRs (kil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d3a0f4a714c5d6cda81d3fb63ffacc
https://europepmc.org/articles/PMC9948998/
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje