Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Susan E. Detmer"'
Autor:
Cody W. Koloski, Georgia Hurry, Alexandra Foley-Eby, Hesham Adam, Savannah Goldstein, Pini Zvionow, Susan E. Detmer, Maarten J. Voordouw
Publikováno v:
Ticks and Tick-Borne Diseases, Vol 15, Iss 2, Pp 102308- (2024)
Borrelia burgdorferi is a tick-borne spirochete that causes Lyme disease in humans. The host immune system controls the abundance of the spirochete in the host tissues. Recent work with immunocompetent Mus musculus mice strain C3H/HeJ found that male
Externí odkaz:
https://doaj.org/article/ed3e73e7977549209a1de6e5bb5bc769
Autor:
Carolina M. Malgarin, Fiona Moser, J. Alex Pasternak, Glenn Hamonic, Susan E. Detmer, Daniel J. MacPhee, John C. S. Harding
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-14 (2021)
Abstract Background Mechanisms of fetal death following maternal PRRSV2 infection remain uncharacterized, although hypoxia from umbilical cord lesions and/or placental detachment due to apoptosis are hypothesized. We performed two experiments examini
Externí odkaz:
https://doaj.org/article/4302054c76e943c1aeec65c40821b847
Autor:
Javier A. Barrera-Zarate, Susan E. Detmer, J. Alex Pasternak, Glenn Hamonic, Daniel J. MacPhee, John C. S. Harding
Publikováno v:
Veterinary Pathology. 59:940-949
Angiogenesis and cell proliferation in reproductive tissues are essential events for the maintenance of pregnancy, and alterations can lead to compromised fetal development and survival. Porcine reproductive and respiratory syndrome virus 2 (PRRSV-2)
Autor:
J. Alex Pasternak, Fiona Moser, Daniel J. MacPhee, John C. S. Harding, Susan E. Detmer, Glenn Hamonic, Carolina M. Malgarin
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-14 (2021)
BMC Veterinary Research
BMC Veterinary Research
Background Mechanisms of fetal death following maternal PRRSV2 infection remain uncharacterized, although hypoxia from umbilical cord lesions and/or placental detachment due to apoptosis are hypothesized. We performed two experiments examining hypoxi
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173360 (2017)
The pathogenesis of fetal death associated with porcine reproductive and respiratory syndrome (PRRS) is hypothesized to be a consequence of PRRS virus-induced apoptosis at the maternal-fetal interface (MFI). The objectives of this study were to evalu
Externí odkaz:
https://doaj.org/article/87e513b01785436497759aeb23ac42c1
Autor:
Susan E. Detmer, Daniel J. MacPhee, Carolina M. Malgarin, Javier B. Zarate, John C. S. Harding, Predrag Novakovic
Publikováno v:
Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Porcine reproductive and respiratory syndrome virus (PRRSV) is transmitted vertically, causing fetal death in late gestation. Spatiotemporal distribution of virus at the maternal–fetal interface (MFI) is variable, and accurate assessment of viral c
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151198 (2016)
The pathogenesis of fetal death caused by porcine reproductive and respiratory syndrome virus (PRRSV) remains unclear. The objective of this study was to improve our understanding of the pathogenesis by assessing potential relationships between speci
Externí odkaz:
https://doaj.org/article/47d144716a9f4239bad1927be045b076
Autor:
Jamie M Wilkinson, Rayna E Gunvaldsen, Susan E Detmer, Michael K Dyck, Walter T Dixon, George R Foxcroft, Graham S Plastow, John C S Harding
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138653 (2015)
Influenza viruses are a common cause of respiratory disease in swine. Infections range in severity from asymptomatic to causing significant morbidity. The main objective of this study was to compare lung transcriptomic and epigenetic responses to inf
Externí odkaz:
https://doaj.org/article/771643365c7444dc84d20b94c8741537
Autor:
Javier Barrera-Zarate, Susan E. Detmer, J. Alex Pasternak, Glenn Hamonic, Daniel J. MacPhee, John C.S. Harding
Publikováno v:
Veterinary Immunology and Immunopathology. 250:110457
The porcine epitheliochorial placenta creates a barrier for the transplacental transfer of some nutrients from the dam to the fetus, as well as feto-lethal viruses such as porcine reproductive and respiratory syndrome virus 2 (PRRSV-2). Areolae are s
Autor:
Andrea Ladinig, Jamie Wilkinson, Carolyn Ashley, Susan E Detmer, Joan K Lunney, Graham Plastow, John C S Harding
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96104 (2014)
In spite of extensive research, the mechanisms of reproductive disease associated with Porcine Reproductive and Respiratory Syndrome virus (PRRSv) are still poorly understood. The objectives of this large scale study were to evaluate associations bet
Externí odkaz:
https://doaj.org/article/b13bea450cb74ddca7aa53cedd731ed5