Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Susan E. Brophy"'
Autor:
Philip M. Hemken, Nicolette M. Jeanblanc, Tracey Rae, Susan E. Brophy, Maria J. Datwyler, Ying Xu, T. Scott Manetz, Inna Vainshtein, Meina Liang, Xiaodong Xiao, Partha S. Chowdhury, Chien-ying Chang, Katie Streicher, Lydia Greenlees, Koustubh Ranade, Gerard J. Davis
Publikováno v:
Practical Laboratory Medicine, Vol 9, Iss , Pp 58-68 (2017)
Background: Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the interleukin-13 (IL-13) pathway and may therefore benefit from IL-13-targeted treatments. We report the ana
Externí odkaz:
https://doaj.org/article/b5d2f2e9efc14bc1853381f654d6d33b
Autor:
Joan D. Tyner, David J. Hawksworth, Bailin Tu, Bryan C. Tieman, A. Scott Muerhoff, Susan E. Brophy, Robert Ziemann
Publikováno v:
Hybridoma. 31:436-442
Development of a robust immunoassay requires the selection of monoclonal antibodies with desired properties. These properties generally include kinetics parameters such as on-rate and off-rate (i.e., binding affinity), and, often times, the ability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fe261dd169a532cc23f744df5ed8ed
https://doi.org/10.1089/hyb.2012.0055
https://doi.org/10.1089/hyb.2012.0055
Autor:
David J. Hawksworth, Susan E. Brophy, Bryan C. Tieman, Mary S. Pinkus, James W. Scheffel, Bailin Tu, Jeffrey M. Werneke, Joan D. Tyner, Robin A. Gutierrez, Robert Ziemann, Michael K. White
Publikováno v:
Clinical and Vaccine Immunology. 17:1040-1047
Mouse-human chimeric antibodies (cAbs) against hepatitis C virus (HCV) core, NS3 (nonstructural), NS4, and NS5 antigens were developed as quality control (QC) reagents to replace the use of human sera/plasma for Abbott HCV immunoassays. The cAb retai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221030ee82db81371df2ca4a43dac3ec
https://doi.org/10.1128/cvi.00068-10
https://doi.org/10.1128/cvi.00068-10
Autor:
Sergey Y. Tetin, Kenton L. Longenecker, Elizabeth H. Fry, Qiaoqiao Ruan, Paul L. Richardson, Susan E. Brophy, Sylvia C. Saldana
Publikováno v:
Proteins. 76(3)
B-type natriuretic peptide (BNP) is a naturally secreted regulatory hormone that influences blood pressure and vascular water retention in human physiology. The plasma BNP concentration is a clinically recognized biomarker for various cardiovascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff3e658fcb7fca8d3490819217b6c5a
https://pubmed.ncbi.nlm.nih.gov/19274732
https://pubmed.ncbi.nlm.nih.gov/19274732
Autor:
David M. Kranz, Leremy A. Colf, Nicole A. Hanick, Alexander J. Bankovich, K. Christopher Garcia, Lindsay L. Jones, Susan E. Brophy
Publikováno v:
The Journal of biological chemistry. 281(35)
The major histocompatibility complex (MHC) is the most polymorphic locus known, with thousands of allelic variants. There is considerable interest in understanding the diversity of structures and peptide-binding features represented by this class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2016fc6b2645ffdbe2633a18a0a8523c
https://pubmed.ncbi.nlm.nih.gov/16815841
https://pubmed.ncbi.nlm.nih.gov/16815841
Publikováno v:
Journal of immunological methods. 272(1-2)
In a cellular immune response, antigenic peptides derived by intracellular processing of foreign pathogens are bound to the class I major histocompatability complex (MHC I) and presented to CD8(+) cytotoxic T cells. Although the crystal structures of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adab0a2cda19fe56cc49e78a5f7d66c
https://pubmed.ncbi.nlm.nih.gov/12505727
https://pubmed.ncbi.nlm.nih.gov/12505727