Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Susan E Spiller"'
Publikováno v:
Pediatric bloodcancerREFERENCES. 68(6)
Larger clinical trial enrollments and a greater understanding of biological heterogeneity have led to improved survival rates for children diagnosed with brain tumors in the last 50 years. However, reducing long-term morbidities and improving surviva
Autor:
Daniel C. Moreira, Susan E. Spiller, Aaron S. Wagner, Alan Davidson, Thomas W. Bouldin, Nasjla Saba-Silva, Ryuma Tanaka, Matthew D. Wood, Daniel C. Sullivan, Jason Chiang, Amar Gajjar
Publikováno v:
Neuro-Oncology
Background Pediatric diffuse gliomas harbor recurrent genetic alterations, including those in MYB and MYBL1. Regardless of histopathologic classification, low-grade diffuse gliomas with MYB/MYBL1 alterations represent a single disease entity. Additio
Publikováno v:
Journal of Neuro-Oncology. 79:259-270
Suberoylanilide hydroxamic acid (SAHA) has been studied in adult solid and hematologic malignancies. However, little information has been reported on the effects of SAHA on central nervous system (CNS) tumors including medulloblastoma, the most commo
Publikováno v:
Pediatric Blood & Cancer. 45:60-63
Malignant melanoma is rare in childhood and has never been reported to cause pancytopenia due to bone marrow metastases in a child. We report a 3-year-old boy with a large congenital melanocytic nevus who presented with bone pain and pancytopenia due
Publikováno v:
Journal of pediatric hematology/oncology. 35(3)
Prognosis for children with glioblastoma is unacceptably poor. Modest improvements in progression-free survival were seen in adults with glioblastoma by combining temozolomide and bevacizumab with conformal radiation. We retrospectively reviewed 3 ca
Publikováno v:
The Journal of membrane biology. 237(2-3)
Medulloblastoma is a pediatric high-grade cerebellar malignancy derived from neuronal precursors. Although electrophysiologic characteristics of cerebellar granule neurons at all stages of cell development have been well described, such characterizat
Publikováno v:
Journal of neuro-oncology. 87(2)
Purpose Current medulloblastoma therapy, surgery, radiation, and chemotherapy, is unacceptably toxic. However, 13-cis retinoic acid (RA) and SAHA, a histone deacetylase inhibitor, have each been shown to induce apoptosis in medulloblastoma cultures a
Publikováno v:
BMC Cancer
BMC Cancer, Vol 11, Iss 1, p 136 (2011)
BMC Cancer, Vol 11, Iss 1, p 136 (2011)
Background Medulloblastoma is a highly malignant pediatric brain tumor that requires surgery, whole brain and spine irradiation, and intense chemotherapy for treatment. A more sophisticated understanding of the pathophysiology of medulloblastoma is n
Publikováno v:
Pediatric Blood & Cancer; Jun2021, Vol. 68 Issue 6, p1-16, 16p
Autor:
Friedman, Gregory K., Spiller, Susan E., Harrison, D. Keith, Fiveash, John B., Reddy, Alyssa T.
Publikováno v:
Journal of Pediatric Hematology/Oncology; Apr2013, Vol. 35 Issue 3, pe123-e126, 4p