Zobrazeno 1 - 10
of 369
pro vyhledávání: '"Susan E Murray"'
Autor:
Michael W Munks, Katherine Rott, Pavlo A Nesterenko, Savannah M Smart, Venasha Williams, Angela Tatum, Guangwu Xu, Tameka Smith, Susan E Murray, Ann B Hill
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1010351 (2023)
CMV, a ubiquitous herpesvirus, elicits an extraordinarily large T cell response that is sustained or increases over time, a phenomenon termed 'memory inflation.' Remarkably, even latent, non-productive infection can drive memory inflation. Despite in
Externí odkaz:
https://doaj.org/article/95e2f51f80464c72a12f15090ab3ddc7
Autor:
Xiangnan Guan, Fanny Polesso, Chaojie Wang, Archana Sehrawat, Reed M. Hawkins, Susan E. Murray, George V. Thomas, Breanna Caruso, Reid F. Thompson, Mary A. Wood, Christina Hipfinger, Scott A. Hammond, Julie N. Graff, Zheng Xia, Amy E. Moran
Publikováno v:
Nature
Immune checkpoint blockade has revolutionized the field of oncology, inducing durable anti-tumour immunity in solid tumours. In patients with advanced prostate cancer, immunotherapy treatments have largely failed(1–5). Androgen deprivation therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc63a86a2e2dff5be83bc4c982c45456
https://europepmc.org/articles/PMC10294141/
https://europepmc.org/articles/PMC10294141/
Autor:
Michael W. Munks, Katherine Rott, Pavlo A. Nesterenko, Savannah M. Smart, Venasha Williams, Angela Tatum, George Xu, Tameka Smith, Susan E. Murray, Ann B. Hill
CMV, a ubiquitous herpesvirus, elicits an extraordinarily large T cell response that is sustained or increases over time, a phenomenon termed ‘memory inflation.’ Remarkably, even latent, non-productive infection can drive memory inflation. Despit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e221f51f28fa806aae239bd84cf4465d
https://doi.org/10.1101/2022.02.10.479848
https://doi.org/10.1101/2022.02.10.479848
Publikováno v:
Cellular Immunology. 384:104674
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8db4d864b01919f719934d5ad4f19d
https://doi.org/10.1016/j.cellimm.2023.104674
https://doi.org/10.1016/j.cellimm.2023.104674
Secondary mitochondria-derived activator of caspases (SMAC) mimetics are being tested in dozens of clinical trials to treat cancer. These targeted therapies mimic endogenous molecules that promote apoptosis by antagonizing inhibitors of apoptosis (IA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12fff8e79754f793dd2597de660282c6
https://doi.org/10.1101/2021.11.09.466489
https://doi.org/10.1101/2021.11.09.466489
Autor:
Susan E Murray
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76216 (2013)
NF-κB inducing kinase (NIK, MAP3K14) is a key signaling molecule in non-canonical NF-κB activation, and NIK deficient mice have been instrumental in deciphering the immunologic role of this pathway. Global ablation of NIK prevents lymph node develo
Externí odkaz:
https://doaj.org/article/36206e4e658b41ef8adbc98477159214
Autor:
Xiangnan, Guan, Fanny, Polesso, Chaojie, Wang, Archana, Sehrawat, Reed M, Hawkins, Susan E, Murray, George V, Thomas, Breanna, Caruso, Reid F, Thompson, Mary A, Wood, Christina, Hipfinger, Scott A, Hammond, Julie N, Graff, Zheng, Xia, Amy E, Moran
Publikováno v:
Nature. 606(7915)
Immune checkpoint blockade has revolutionized the field of oncology, inducing durable anti-tumour immunity in solid tumours. In patients with advanced prostate cancer, immunotherapy treatments have largely failed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c049b7972a71fbb687882ecd87b55d5
https://pubmed.ncbi.nlm.nih.gov/35776801
https://pubmed.ncbi.nlm.nih.gov/35776801
Autor:
Evan F. Lind, Vi Lam, Nathan D. Pennock, Scott R Best, Adam Kittai, Alexey V. Danilov, Nur Bruss, Allison Berger, Susan E. Murray, Tingting Liu, Olga V. Danilova
Publikováno v:
Leukemia
Novel targeted agents used in therapy of lymphoid malignancies, such as inhibitors of B-cell receptor-associated kinases, are recognized to have complex immune-mediated effects. NEDD8-activating enzyme (NAE) has been identified as a tractable target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcae410fe576a9e2b7a646012b4569dc
https://europepmc.org/articles/PMC8288064/
https://europepmc.org/articles/PMC8288064/
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports
Scientific Reports
CD4+Foxp3+ regulatory T cells (Tregs) are indispensable negative regulators of immune responses. To understand Treg biology in health and disease, it is critical to elucidate factors that affect Treg homeostasis and suppressive function. Tregs expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597ffd0267324f168e95df0421367685
http://link.springer.com/article/10.1038/s41598-017-14965-x
http://link.springer.com/article/10.1038/s41598-017-14965-x
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 203(7)
OX40 is a costimulatory molecule from the TNFR family. In mice, it is expressed on Foxp3+ regulatory T cells (Tregs) constitutively and on conventional CD4 (Tconv) and CD8 T cells after Ag encounter. OX40 agonists are in clinical development to enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36927422f6154b1343268eef9f91146b
https://pubmed.ncbi.nlm.nih.gov/31434709
https://pubmed.ncbi.nlm.nih.gov/31434709