Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Susan E Birket"'
Autor:
Meghan J Hirsch, Emily M Hughes, Molly M Easter, Seth E Bollenbecker, Patrick H Howze Iv, Susan E Birket, Jarrod W Barnes, Megan R Kiedrowski, Stefanie Krick
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288002 (2023)
Pseudomonas aeruginosa (PA) is known to chronically infect airways of people with cystic fibrosis (CF) by early adulthood. PA infections can lead to increased airway inflammation and lung tissue damage, ultimately contributing to decreased lung funct
Externí odkaz:
https://doaj.org/article/43c2aaaec5e346c587bb2106b54b43b3
Autor:
Wesley R Lewis, Erik B Malarkey, Douglas Tritschler, Raqual Bower, Raymond C Pasek, Jonathan D Porath, Susan E Birket, Sophie Saunier, Corinne Antignac, Michael R Knowles, Margaret W Leigh, Maimoona A Zariwala, Anil K Challa, Robert A Kesterson, Steven M Rowe, Iain A Drummond, John M Parant, Friedhelm Hildebrandt, Mary E Porter, Bradley K Yoder, Nicolas F Berbari
Publikováno v:
PLoS Genetics, Vol 12, Iss 7, p e1006220 (2016)
Ciliopathies are genetic disorders arising from dysfunction of microtubule-based cellular appendages called cilia. Different cilia types possess distinct stereotypic microtubule doublet arrangements with non-motile or 'primary' cilia having a 9+0 and
Externí odkaz:
https://doaj.org/article/7c98f36db5424abc93f80eefd82caaec
Autor:
Katherine L Tuggle, Susan E Birket, Xiaoxia Cui, Jeong Hong, Joe Warren, Lara Reid, Andre Chambers, Diana Ji, Kevin Gamber, Kengyeh K Chu, Guillermo Tearney, Li Ping Tang, James A Fortenberry, Ming Du, Joan M Cadillac, David M Bedwell, Steven M Rowe, Eric J Sorscher, Michelle V Fanucchi
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91253 (2014)
Animal models for cystic fibrosis (CF) have contributed significantly to our understanding of disease pathogenesis. Here we describe development and characterization of the first cystic fibrosis rat, in which the cystic fibrosis transmembrane conduct
Externí odkaz:
https://doaj.org/article/cda01f9339b140bb92a4e09c988812c8
Autor:
Linbo Liu, Kengyeh K Chu, Grace H Houser, Bradford J Diephuis, Yao Li, Eric J Wilsterman, Suresh Shastry, Gregory Dierksen, Susan E Birket, Marina Mazur, Suzanne Byan-Parker, William E Grizzle, Eric J Sorscher, Steven M Rowe, Guillermo J Tearney
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54473 (2013)
We demonstrate the use of a high resolution form of optical coherence tomography, termed micro-OCT (μOCT), for investigating the functional microanatomy of airway epithelia. μOCT captures several key parameters governing the function of the airway
Externí odkaz:
https://doaj.org/article/61e069d290a545849900ae2dc4fe1941
Autor:
Johnathan D. Keith, Alexander G. Henderson, Courtney M. Fernandez-Petty, Joy M. Davis, Ashley M. Oden, Susan E. Birket
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Cystic fibrosis (CF) airway disease is characterized by excessive and accumulative mucus in the airways. Mucociliary clearance becomes defective as mucus secretions become hyperconcentrated and viscosity increases. The CFTR-knockout (KO) rat has been
Externí odkaz:
https://doaj.org/article/d0506cadbe8a463e9c94940acdad5073
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Nonsense mutations that lead to the insertion of a premature termination codon (PTC) in the cystic fibrosis transmembrane conductance regulator (CFTR) transcript affect 11% of patients with cystic fibrosis (CF) worldwide and are associated with sever
Externí odkaz:
https://doaj.org/article/5962659aafb74aafbefe9f8a31e4a5db
Autor:
Suki Albers, Elizabeth C. Allen, Nikhil Bharti, Marcos Davyt, Disha Joshi, Carlos G. Perez-Garcia, Leonardo Santos, Rajesh Mukthavaram, Miguel Angel Delgado-Toscano, Brandon Molina, Kristen Kuakini, Maher Alayyoubi, Kyoung-Joo Jenny Park, Grishma Acharya, Jose A. Gonzalez, Amit Sagi, Susan E. Birket, Guillermo J. Tearney, Steven M. Rowe, Candela Manfredi, Jeong S. Hong, Kiyoshi Tachikawa, Priya Karmali, Daiki Matsuda, Eric J. Sorscher, Pad Chivukula, Zoya Ignatova
Publikováno v:
Nature.
Nonsense mutations are the underlying cause of approximately 11% of all inherited genetic diseases1. Nonsense mutations convert a sense codon that is decoded by tRNA into a premature termination codon (PTC), resulting in an abrupt termination of tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce16bd9fcf8f08df04e467cccb0f4594
https://doi.org/10.1038/s41586-023-06133-1
https://doi.org/10.1038/s41586-023-06133-1
Autor:
Joseph Zabner, Susan E. Birket
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7ac55280f433022a279dde514a5c0c3
https://doi.org/10.1165/rcmb.2023-0096ed
https://doi.org/10.1165/rcmb.2023-0096ed
Autor:
Linhui Yu, Courtney F. Petty, Hui Min Leung, Susan E. Birket, Steven M. Rowe, Guillermo J. Tearney
Publikováno v:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28e736e834b5a326b01df1ee70be4a28
https://doi.org/10.1117/12.2650168
https://doi.org/10.1117/12.2650168
Autor:
Linhui Yu, Hui M. Leung, Courtney F. Petty, Anagha Arvind, Miquela O. Murray, Susan E. Birket, Steven M. Rowe, Guillermo J. Tearney
Publikováno v:
Multimodal Biomedical Imaging XVIII.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1d43d2dc985b1f61e87fe33c40d5a2
https://doi.org/10.1117/12.2649211
https://doi.org/10.1117/12.2649211