Zobrazeno 1 - 10
of 563
pro vyhledávání: '"Susan E Bates"'
Autor:
Harshraj Leuva, Mengxi Zhou, Nader Jamaleddine, Mina Meseha, Izak Faiena, Yeun-Hee Anna Park, Glen McWilliams, Carol Luhrs, Kara N. Maxwell, Daniel Von Hoff, Susan E. Bates, Tito Fojo
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105288- (2024)
Summary: Background: We aimed to assess real-world efficacy of the PARP inhibitor, olaparib, in US Veterans with metastatic prostate cancer (mPC) by leveraging the national data repository and evaluate a novel approach to assess treatment efficacy in
Externí odkaz:
https://doaj.org/article/334a7c499ee34aacbe5585cb079f89ea
Autor:
Maryam Safari, Luigi Scotto, Thomas Litman, Lubov A. Petrukhin, Hu Zhu, Min Shen, Robert W. Robey, Matthew D. Hall, Tito Fojo, Susan E. Bates
Publikováno v:
Cancers, Vol 15, Iss 20, p 4960 (2023)
Background: Over the last few decades of treatment, the outcomes for at least some subsets of neuroendocrine neoplasms (NENs) have improved. However, the identification of new vulnerabilities for this heterogeneous group of cancers remains a priority
Externí odkaz:
https://doaj.org/article/2ee86906d8cc4b10aef7f342dc0230a7
Autor:
Robyn D. Gartrell, Thomas Enzler, Pan S. Kim, Benjamin T. Fullerton, Ladan Fazlollahi, Andrew X. Chen, Hanna E. Minns, Subha Perni, Stuart P. Weisberg, Emanuelle M. Rizk, Samuel Wang, Eun Jeong Oh, Xinzheng V. Guo, Codruta Chiuzan, Gulam A. Manji, Susan E. Bates, John Chabot, Beth Schrope, Michael Kluger, Jean Emond, Raul Rabadán, Donna Farber, Helen E. Remotti, David P. Horowitz, Yvonne M. Saenger
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Patients with pancreatic ductal adenocarcinoma (PDAC) have a grim prognosis despite complete surgical resection and intense systemic therapies. While immunotherapies have been beneficial with many different types of solid tumors, they have almost uni
Externí odkaz:
https://doaj.org/article/0131345f4fd04318adad2908f6c64b94
Autor:
Mohamed Abou-el-Enein, Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman, Malcolm K. Brenner, Marina Cavazzana, Michael A. Caligiuri, Hans Clevers, Emer Cooke, George Q. Daley, Victor J. Dzau, Lee M. Ellis, Harvey V. Fineberg, Lawrence S.B. Goldstein, Stephen Gottschalk, Margaret A. Hamburg, Donald E. Ingber, Donald B. Kohn, Adrian R. Krainer, Marcela V. Maus, Peter Marks, Christine L. Mummery, Roderic I. Pettigrew, Joni L. Rutter, Sarah A. Teichmann, Andre Terzic, Fyodor D. Urnov, David A. Williams, Jedd D. Wolchok, Mark Lawler, Cameron J. Turtle, Gerhard Bauer, John P.A. Ioannidis
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 11-14 (2021)
Externí odkaz:
https://doaj.org/article/c3fa45c6e32349f68ffd7fcab701dc16
Autor:
Myles A. Ingram, Brianna N. Lauren, Yoanna Pumpalova, Jiheum Park, Francesca Lim, Susan E. Bates, Fay Kastrinos, Gulam A. Manji, Chung Yin Kong, Chin Hur
Publikováno v:
Cancer Reports, Vol 5, Iss 9, Pp n/a-n/a (2022)
Abstract Background The 2020 National Comprehensive Cancer Network guidelines recommend neoadjuvant FOLFIRINOX or neoadjuvant gemcitabine plus nab‐paclitaxel (G‐nP) for borderline resectable/locally advanced pancreatic ductal adenocarcinoma (BR/L
Externí odkaz:
https://doaj.org/article/e421dd6448d6472fab80e7690d3e02c8
Autor:
Emily L. Giddings, Devin P. Champagne, Meng-Han Wu, Joshua M. Laffin, Tina M. Thornton, Felipe Valenca-Pereira, Rachel Culp-Hill, Karen A. Fortner, Natalia Romero, James East, Phoebe Cao, Hugo Arias-Pulido, Karatatiwant S. Sidhu, Brian Silverstrim, Yoonseok Kam, Shana Kelley, Mark Pereira, Susan E. Bates, Janice Y. Bunn, Steven N. Fiering, Dwight E. Matthews, Robert W. Robey, Domink Stich, Angelo D’Alessandro, Mercedes Rincon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Drug efflux through ABC transporters is a common mechanism leading to chemoresistance in cancer. Here, the authors show that mitochondrial respiration provides ATP to allow ABC transporters activity so mitochondrial respiration inhibition overcomes c
Externí odkaz:
https://doaj.org/article/96cc5e262fc1481b86eceff834f1a9ce
Autor:
Tito Fojo, Lyn Huff, Thomas Litman, Kate Im, Maureen Edgerly, Jaydira del Rivero, Stefania Pittaluga, Maria Merino, Susan E. Bates, Michael Dean
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Background Adrenocortical carcinoma (ACC) is a rare, often-aggressive neoplasm of the adrenal cortex, with a 14–17 month median overall survival. We asked whether tumors from patients with advanced or metastatic ACC would offer clues as to
Externí odkaz:
https://doaj.org/article/178a94f70ba546e1a2a2186d45d7c3c6
Autor:
Sharyn D. Baker, Susan E. Bates, Gabriel A. Brooks, William L. Dahut, Robert B. Diasio, Wafik S. El-Deiry, William E. Evans, William D. Figg, Dan L. Hertz, J. Kevin Hicks, Suneel Kamath, Pashtoon Murtaza Kasi, Todd C. Knepper, Howard L. McLeod, Peter H. O'Donnell, Mary V. Relling, Michelle A. Rudek, Tristan M. Sissung, D. Max Smith, Alex Sparreboom, Sandra M. Swain, Christine M. Walko
Publikováno v:
Journal of Clinical Oncology. 41:2701-2705
Autor:
Agnes Basseville, Pierre-Christian Violet, Maryam Safari, Carole Sourbier, W. Marston Linehan, Robert W. Robey, Mark Levine, Dan L. Sackett, Susan E. Bates
Publikováno v:
Cancers, Vol 14, Iss 11, p 2643 (2022)
Background: The mechanism of action of romidepsin and other histone deacetylase inhibitors is still not fully explained. Our goal was to gain a mechanistic understanding of the RAS-linked phenotype associated with romidepsin sensitivity. Methods: The
Externí odkaz:
https://doaj.org/article/4c3392b5d41d47bca056e280c9654e77
Supplementary Figures S1-S6 from Histone Modifications at the ABCG2 Promoter following Treatment with Histone Deacetylase Inhibitor Mirror Those in Multidrug-Resistant Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa0cb9ac36ecc8b6e3ee67dbbb6f206
https://doi.org/10.1158/1541-7786.22521304
https://doi.org/10.1158/1541-7786.22521304