Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Susan Dent"'
Autor:
Michelle Bloom, Jose A. Alvarez-Cardona, Sarju Ganatra, Ana Barac, Iskra Pusic, Daniel Lenihan, Susan Dent
Publikováno v:
Cardio-Oncology, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Heart failure (HF) in patients with cancer is associated with high morbidity and mortality. The success of cancer therapy has resulted in an exponential rise in the population of cancer survivors, however cardiovascular disease (CVD) is now
Externí odkaz:
https://doaj.org/article/f3a584b5941c46819cccf9e938764430
Autor:
Omar M. Makram, Tochukwu Okwuosa, Daniel Addison, Jorge Cortes, Susan Dent, Malcolm Bevel, Sarju Ganatra, Sadeer Al‐Kindi, Catherine C Hedrick, Neal L Weintraub, Xiaoling Wang, Avirup Guha
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Both cancer and cardiovascular disease (CVD) are the leading causes of death worldwide. Although our previous study detected a relationship between CVD and cancer incidence, limited evidence is available regarding the relationship between
Externí odkaz:
https://doaj.org/article/80024f6239cd41fabdebb1ffd099382e
Autor:
Nickolas Stabellini, Jennifer Cullen, Marcio S. Bittencourt, Justin X. Moore, Arnethea Sutton, Priyanshu Nain, Nelson Hamerschlak, Neal L. Weintraub, Susan Dent, Meng‐Han Tsai, Amitava Banerjee, Arjun K Ghosh, Diego Sadler, Steven S. Coughlin, Ana Barac, John Shanahan, Alberto J. Montero, Avirup Guha
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Cardiovascular disease and cancer share a common risk factor: chronic stress/allostatic load (AL). A 1‐point increase in AL is linked to up to a 30% higher risk of major cardiac events (MACE) in patients with prostate cancer. However, AL
Externí odkaz:
https://doaj.org/article/7618f7b4375e4dc3988926621ce3be61
Autor:
Jessica W. Chen, William Jacot, Javier Cortés, Ian E. Krop, Susan Dent, Nadia Harbeck, Michelino De Laurentiis, Véronique Diéras, Young‐Hyuck Im, Thomas J. Stout, Frauke Schimmoller, Heidi M. Savage, Katherine E. Hutchinson, Timothy R. Wilson
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2000-2016 (2023)
Taselisib is a potent β‐sparing phosphatidylinositol 3‐kinase (PI3K) inhibitor that, with endocrine therapy, improves outcomes in phosphatidylinositol‐4,5‐bisphosphate 3‐kinase catalytic subunit alpha (PIK3CA)‐mutated (PIK3CAmut) advance
Externí odkaz:
https://doaj.org/article/535a6a7921404a8298c1f95b55637007
Autor:
Katherine E. Hutchinson, Jessica W. Chen, Heidi M. Savage, Thomas J. Stout, Frauke Schimmoller, Javier Cortés, Susan Dent, Nadia Harbeck, William Jacot, Ian Krop, Sally E. Trabucco, Smruthy Sivakumar, Ethan S. Sokol, Timothy R. Wilson
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Mutations in the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K), encoded by the PIK3CA gene, cause dysregulation of the PI3K pathway in 35–40% of patients with HR+/HER2– breast cancer. Preclinically, cancer c
Externí odkaz:
https://doaj.org/article/6a84c1824dfc43c99cd063f56d446e86
Autor:
Gillian Murtagh, James L. Januzzi, Marielle Scherrer‐Crosbie, Tomas G. Neilan, Susan Dent, Jennifer E. Ho, Vinesh Appadurai, Ray McDermott, Nausheen Akhter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
ABSTRACT Cardiotoxicity is a growing concern in the oncology population. Transthoracic echocardiography and multigated acquisition scans have been used for surveillance but are relatively insensitive and resource intensive. Innovative imaging techniq
Externí odkaz:
https://doaj.org/article/fff5d80966a54a05b23e19381cc66a9c
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/892215f7201a42ec97ef0f4ea7a0d376
Autor:
Melissa Y.Y. Moey, Cassandra Hennessy, Benjamin French, Jeremy L. Warner, Matthew D. Tucker, Daniel J. Hausrath, Dimpy P. Shah, Jeanne M. DeCara, Ziad Bakouny, Chris Labaki, Toni K. Choueiri, Susan Dent, Nausheen Akhter, Roohi Ismail-Khan, Lisa Tachiki, David Slosky, Tamar S. Polonsky, Joy A. Awosika, Audrey Crago, Trisha Wise-Draper, Nino Balanchivadze, Clara Hwang, Leslie A. Fecher, Cyndi Gonzalez Gomez, Brandon Hayes-Lattin, Michael J. Glover, Sumit A. Shah, Dharmesh Gopalakrishnan, Elizabeth A. Griffiths, Daniel H. Kwon, Vadim S. Koshkin, Sana Mahmood, Babar Bashir, Taylor Nonato, Pedram Razavi, Rana R. McKay, Gayathri Nagaraj, Eric Oligino, Matthew Puc, Polina Tregubenko, Elizabeth M. Wulff-Burchfield, Zhuoer Xie, Thorvardur R. Halfdanarson, Dimitrios Farmakiotis, Elizabeth J. Klein, Elizabeth V. Robilotti, Gregory J. Riely, Jean-Bernard Durand, Salim S. Hayek, Lavanya Kondapalli, Stephanie Berg, Timothy E. O'Connor, Mehmet A. Bilen, Cecilia Castellano, Melissa K. Accordino, Blau Sibel, Lisa B. Weissmann, Chinmay Jani, Daniel B. Flora, Lawrence Rudski, Miriam Santos Dutra, Bouganim Nathaniel, Erika Ruíz-García, Diana Vilar-Compte, Shilpa Gupta, Alicia Morgans, Anju Nohria
Publikováno v:
Translational Oncology, Vol 34, Iss , Pp 101709- (2023)
Background: Data regarding outcomes among patients with cancer and co-morbid cardiovascular disease (CVD)/cardiovascular risk factors (CVRF) after SARS-CoV-2 infection are limited. Objectives: To compare Coronavirus disease 2019 (COVID-19) related co
Externí odkaz:
https://doaj.org/article/9d648aa2b95644a1af71f1806e404101
Autor:
Michael G. Fradley, Nam H. K. Nguyen, David Madnick, Yiqing Chen, Angela DeMichele, Igor Makhlin, Susan Dent, Benedicte Lefebvre, Joseph Carver, Jenica N. Upshaw, David DeRemer, Bonnie Ky, Avirup Guha, Yan Gong
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background Cyclin‐dependent kinase (CDK) 4 and 6 inhibitors have significantly improved survival in patients with hormone receptor–positive metastatic breast cancer. There are few data regarding the epidemiology of cardiovascular adverse events (
Externí odkaz:
https://doaj.org/article/f73097a8c1484ebdafe65151a6a2f245
Autor:
Susan Dent, Dean Fergusson, Olexiy Aseyev, Carol Stober, Gregory Pond, Arif A. Awan, Sharon F. McGee, Terry L. Ng, Demetrios Simos, Lisa Vandermeer, Deanna Saunders, John F. Hilton, Brian Hutton, Mark Clemons
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 5073-5083 (2021)
Purpose: The optimal frequency for cardiac monitoring of left ventricular ejection fraction (LVEF) in patients receiving trastuzumab-based therapy for early breast cancer (EBC) is unknown. We conducted a randomized controlled trial comparing 3- versu
Externí odkaz:
https://doaj.org/article/af20337c49a349a1b33516454764a8cc