Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Susan D. Kent"'
Autor:
Uma M Sharma, R Christopher Chase, Jitka A. I. Virag, Susan D. Kent, Victoria A Chan, Maliha Bhuiyan, Smrithi Valsaraj, K'Shylah S Whitehurst, Heather K Estes
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5811, p 5811 (2020)
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5811, p 5811 (2020)
Background: EphrinA1-Fc abolishes acute I/R injury and attenuates nonreperfused cardiac injury 4 days after permanent occlusion in mice. The goal of this study was to assess the capacity of a single intramyocardial administration of ephrinA1-Fc at th
Publikováno v:
The Journal of Physiology. 589:1725-1740
The purpose of this study was to investigate the role of intramyocardial administration of chimeric ephrinA1-Fc in modulating the extent of injury and inflammation in non reperfused myocardial infarction (MI). Our results show that intramyocardial in
Autor:
Jackson R Vuncannon, Jonathan Hodges, Wesley T. O'Neal, Susan D. Kent, Filza Faiz, Jitka A. I. Virag, William F. Griffin
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 5 (2014)
Frontiers in Physiology, Vol 5 (2014)
EphrinA1-EphA-receptor signaling is protective during myocardial infarction (MI). The EphA2-receptor (EphA2-R) potentially mediates cardiomyocyte survival. To determine the role of the EphA2-R in acute non-reperfused myocardial injury in vivo, infarc
Publikováno v:
Cardiovascular Diabetology
Background We have previously shown that EphrinA1/EphA expression profile changes in response to myocardial infarction (MI), exogenous EphrinA1-Fc administration following MI positively influences wound healing, and that deletion of the EphA2 Recepto
Autor:
Robert M. Lust, Kathleen Thayne, Susan D. Kent, Tracy L. Johnson, Ethan J. Anderson, Harrison D. Blanton, Jonathan DeAntonio, Jitka A. I. Virag, Fatiha Moukdar, Jian Ding
We have previously shown that myocardial infarct size in nonreperfused hearts of mice with a functional deletion of the circadian rhythm gene mPer2 (mPer2-M) was reduced by 43%. We hypothesized that acute ischemia-reperfusion injury (I/R = 30 min I/2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72cb919f3bfc329c2887bd213ec3dba7
https://europepmc.org/articles/PMC3891252/
https://europepmc.org/articles/PMC3891252/
Publikováno v:
Journal of Clinical & Experimental Cardiology.
During acute myocardial infarction (MI), the cumulative loss of functioning cardiomyocytes (CM) progresses as an imbrication of necrosis, apoptosis, and autophagy. Coronary artery occlusion and subsequent hypoxia causes some CMs to undergo necrosis w
Autor:
Susan D. Kent, Jessica L. Dries-Devlin, Jitka A. I. Virag, Monte S. Willis, William F. Griffin, Wesley T. O'Neal, Jin Chen
Although numerous strategies have been developed to reduce the initial ischemic insult and cellular injury that occurs during myocardial infarction (MI), few have progressed into the clinical arena. The epidemiologic and economic impact of MI necessi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1686a7168de4fe0edcf383c2e86826f7
Publikováno v:
The Journal of physiology. 589(Pt 7)
The purpose of this study was to investigate the role of intramyocardial administration of chimeric ephrinA1-Fc in modulating the extent of injury and inflammation in non reperfused myocardial infarction (MI). Our results show that intramyocardial in