Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Susan Conrath"'
Autor:
Laurent Daviet, Rémi Delansorne, Philippe Guedat, Jean-Christophe Rain, Guillaume Boissy, Vincent Collura, Wolfgang Sippl, Catherine Borg-Capra, Alessandra Calabrese, Jacques Camonis, Vasily N. Aushev, Julie Bianchi, Virginie Trouplin, Susan Conrath, Cécile Planquette, Céline Reverdy, Xavier Jacq, Etienne Formstecher, Frédéric Colland
Deregulation of the ubiquitin/proteasome system has been implicated in the pathogenesis of many human diseases, including cancer. Ubiquitin-specific proteases (USP) are cysteine proteases involved in the deubiquitination of protein substrates. Functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b7c9eb0a78d607a3ed0a2185eba838
https://doi.org/10.1158/1535-7163.c.6532221.v1
https://doi.org/10.1158/1535-7163.c.6532221.v1
Autor:
Laurent Daviet, Rémi Delansorne, Philippe Guedat, Jean-Christophe Rain, Guillaume Boissy, Vincent Collura, Wolfgang Sippl, Catherine Borg-Capra, Alessandra Calabrese, Jacques Camonis, Vasily N. Aushev, Julie Bianchi, Virginie Trouplin, Susan Conrath, Cécile Planquette, Céline Reverdy, Xavier Jacq, Etienne Formstecher, Frédéric Colland
Supplementary Data from Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e51112a679de8e29abcc1e35e6f3f6
https://doi.org/10.1158/1535-7163.22486059
https://doi.org/10.1158/1535-7163.22486059
Autor:
Wolfgang Sippl, Xavier Jacq, Philippe Guedat, Julie Bianchi, Alessandra Calabrese, Remi Delansorne, Guillaume Boissy, Frédéric Colland, Cecile Planquette, Virginie Trouplin, Laurent Daviet, Jacques Camonis, Vincent Collura, Céline Reverdy, Catherine Borg-Capra, Jean-Christophe Rain, Susan Conrath, Vasily N. Aushev, Etienne Formstecher
Publikováno v:
Molecular Cancer Therapeutics. 8:2286-2295
Deregulation of the ubiquitin/proteasome system has been implicated in the pathogenesis of many human diseases, including cancer. Ubiquitin-specific proteases (USP) are cysteine proteases involved in the deubiquitination of protein substrates. Functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260d0f5f1750235b0d3467ab67d07cb0
https://doi.org/10.1158/1535-7163.mct-09-0097
https://doi.org/10.1158/1535-7163.mct-09-0097
Autor:
Susan Conrath, Roman Lopez, Philippe Guedat, Vincent Collura, Frédéric Colland, Cecile Planquette, Céline Reverdy, Remi Delansorne, Laurent Daviet
Publikováno v:
Cancer Research. 70:2642-2642
Regulated protein turnover is primarily controlled by the ubiquitin-proteasome system. The only marketed drug related to the ubiquitin-proteasome system, bortezomib, is acting as a proteasome inhibitor and has been approved for the treatment of some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bc2fee96686445df8c6ef40cc8ac272
https://doi.org/10.1158/1538-7445.am10-2642
https://doi.org/10.1158/1538-7445.am10-2642
Autor:
Vincent Collura, Céline Reverdy, Frédéric Colland, Remi Delansorne, Cecile Planquette, Susan Conrath, Roman Lopez, Laurent Daviet, Philippe Guedat
Publikováno v:
Molecular Cancer Therapeutics. 8:B193-B193
Regulated protein turnover is primarily controlled by the ubiquitin-proteasome system. The therapeutic efficacy of the proteasome inhibitor Bortezomib establishes this system as a valid anticancer therapeutic field. A promising alternative to targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6f3e599316612f863e74b4cefcad7af
https://doi.org/10.1158/1535-7163.targ-09-b193
https://doi.org/10.1158/1535-7163.targ-09-b193
Autor:
Roman Lopez, Valérie Vivat, Véronique Battaglia, Wolfgang Sippl, Cédric Atmanene, Céline Reverdy, Frédéric Colland, Cecile Planquette, Jane Harpon, Vincent Collura, Susan Conrath
Publikováno v:
Chemistry & Biology. (4):467-477
SummaryThe human USP7 deubiquitinating enzyme was shown to regulate many proteins involved in the cell cycle, as well as tumor suppressors and oncogenes. Thus, USP7 offers a promising, strategic target for cancer therapy. Using biochemical assays and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753ec3ab5928c76fe89f64b077da98d8