Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan Ciotti"'
Autor:
Pamela T Wong, Pascale R Leroueil, Douglas M Smith, Susan Ciotti, Anna U Bielinska, Katarzyna W Janczak, Catherine H Mullen, Jeffrey V Groom, Erin M Taylor, Crystal Passmore, Paul E Makidon, Jessica J O'Konek, Andrzej Myc, Tarek Hamouda, James R Baker
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126120 (2015)
Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. Despite the potential advantages, however, no mucosa
Externí odkaz:
https://doaj.org/article/4084c3c916ea48baa41149fcafb14c47
Autor:
Emma R Liechty, Stewart C. Wang, Benjamin Levi, Susan Ciotti, James R. Baker, Vladislav A. Dolgachev, Mark R. Hemmila
Publikováno v:
J Burn Care Res
Burn wound progression is an inflammation-driven process where an initial partial-thickness thermal burn wound can evolve over time to a full-thickness injury. We have developed an oil-in-water nanoemulsion formulation (NB-201) containing benzalkoniu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03567a5475b300913e5a11657710781
https://doi.org/10.1093/jbcr/irab118
https://doi.org/10.1093/jbcr/irab118
The Covid-19 pandemic has highlighted the importance of aerosolized droplets inhaled into the nose in the transmission of respiratory viral disease. Inactivating pathogenic viruses at the nasal portal of entry may reduce viral loads, thereby reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::374b2c920958d2baaeca4198aac083ac
https://doi.org/10.1101/2020.11.12.377598
https://doi.org/10.1101/2020.11.12.377598
Autor:
James R. Baker, Linda M. Kalikin, Su He Wang, Susan Ciotti, John E. Wilkinson, Yongyi Fan, Zhengyi Cao, John J. LiPuma, Paul E. Makidon, Theodore Spilker
Publikováno v:
Nanomedicine. 12:1177-1185
Aim: To develop NB-201, a nanoemulsion compound, as a novel microbicidal agent against methicillin-resistant Staphylococcus aureus (MRSA) infection, which is a common threat to public health but with limited therapeutic options. Materials & methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e0119477351e7b6550deb7356c94bf
https://doi.org/10.2217/nnm-2017-0025
https://doi.org/10.2217/nnm-2017-0025
Autor:
Zhengyi Cao, Hugo Acosta, Douglas Smith, Su He Wang, Susan Ciotti, Ali Fattom, Jesse Chen, Yongyi Fan, James R. Baker
Publikováno v:
Vaccine. 38(19)
Background Vaccination is the most effective approach to prevent infection with highly pathogenic avian influenza (HPAI). Adjuvants are often used to induce effective immune responses and overcome the immunological weakness of recombinant HPAI antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3d5b0d866ab1b313a5dcc425484d31
https://pubmed.ncbi.nlm.nih.gov/32245642
https://pubmed.ncbi.nlm.nih.gov/32245642
Self-encapsulating Poly(lactic-co-glycolic acid) (PLGA) Microspheres for Intranasal Vaccine Delivery
Autor:
Susan Ciotti, Lukasz J. Ochyl, James J. Moon, Kashappa Goud H. Desai, Brittany A. Bailey, Steven P. Schwendeman
Publikováno v:
Molecular pharmaceutics. 14(9)
Herein we describe a formulation of self-encapsulating poly(lactic-co-glycolic acid) (PLGA) micro-spheres for vaccine delivery. Self-healing encapsulation is a novel encapsulation method developed by our group that enables the aqueous loading of larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f5726ff8b2eecdbaa3c801d3dbf697
https://pubmed.ncbi.nlm.nih.gov/28726424
https://pubmed.ncbi.nlm.nih.gov/28726424
Autor:
Susan Ciotti, Stephen Gracon, Rone Eisma, Vladislav A. Dolgachev, J. Erby Wilkinson, James R. Baker, Mark R. Hemmila
Publikováno v:
Journal of burn careresearch : official publication of the American Burn Association. 37(2)
The aim of this study is to investigate the antimicrobial efficacy of two different nanoemulsion (NE) formulations against Gram-positive and Gram-negative bacteria in an in vivo rodent scald burn model. Male Sprague-Dawley rats were anesthetized and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0aa7111c49f630d4aafabd0caa82a8a
https://pubmed.ncbi.nlm.nih.gov/26182074
https://pubmed.ncbi.nlm.nih.gov/26182074
Autor:
Pamela T. Wong, James R. Baker, Su He Wang, Susan Ciotti, Charles F. Schuler, Douglas M. Smith, Yongyi Fan, Paul E. Makidon
Publikováno v:
Molecular Pharmaceutics. 11:531-544
The development of effective intranasal vaccines is of great interest due to their potential to induce both mucosal and systemic immunity. Here we produced oil-in-water nanoemulsion (NE) formulations containing various cationic and nonionic surfactan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32cd2608e012e551b7802a442eec553
https://doi.org/10.1021/mp4005029
https://doi.org/10.1021/mp4005029
Publikováno v:
Military medicine. 181
Despite advances in antimicrobial therapies, wound infection remains a global public health concern. We aimed to formulate and assess various nanoemulsions (NEs) for potential effectiveness as stable antimicrobial agents suitable for topic applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416218973b174e186150b6c1ad8deed4
https://pubmed.ncbi.nlm.nih.gov/27168582
https://pubmed.ncbi.nlm.nih.gov/27168582
Autor:
Karen Elaine Sexton, Venkataraman Thanabal, Ann McCarthy, Leroy Lu, Erli Zhang, Maria N. Nguyen, Downs Victoria Leigh, Paul R. Keller, Mark L. Boys, Richard Gowan, Patrick I. McConnell, Edmund L. Ellsworth, Neil Raheja, Richard B. Gilbertsen, Hena Mostafa, Filzen Gary Frederick, N. A. Payne, Feng Bian, Huifen Chen, John D. Knafels, Samarendra N. Maiti, Elena M. Drummond, Stephen Douglas Barrett, Zhi Wang, Larry D. Bratton, Diane Alessi, Deepak S. Lala, Stephen Fakhoury, Sneha Patel, Barry C. Finzel, Susan Ciotti, Iula Donna Michele, Fang Sun, Paul Angell, Xiao Dan Ren, David Pocalyko, Rone Eisma, Kramer James Bernard, Catherine R. Kostlan, Christopher L. Chio
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3392-3397
A series of 2-(1H-pyrazol-1-yl)pyridines are described as inhibitors of ALK5 (TGFβ receptor I kinase). Modeling compounds in the ALK5 kinase domain enabled some optimization of potency via substitutions on the pyrazole core. One of these compounds P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632fe42ba8bb00febbc77151eb92bc8f
https://doi.org/10.1016/j.bmcl.2012.04.013
https://doi.org/10.1016/j.bmcl.2012.04.013