Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Susan Chyou"'
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32828 (2012)
The vascular-stromal elements of lymph nodes can play important roles in regulating the activities of the lymphocytes within. During model immune responses, the vascular-stromal compartment has been shown to undergo proliferative expansion and functi
Externí odkaz:
https://doaj.org/article/a115ae8658c842fd8d5f93efe3360c34
Autor:
Ecem Sevim, Salma Siddique, Madhavi Latha S. Chalasani, Susan Chyou, William D. Shipman, Orla O’Shea, Joanna Harp, Oral Alpan, Stéphane Zuily, Theresa T. Lu, Doruk Erkan
Publikováno v:
The Journal of rheumatology. 49(9)
ObjectiveIn antiphospholipid antibody (aPL) nephropathy, activation of the mammalian target of rapamycin (mTOR) contributes to endothelial cell proliferation, a key finding of aPL microvascular disease. Here, we examined mTOR activation in the skin o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2d882d269e98e55a8d053349448364
https://pubmed.ncbi.nlm.nih.gov/35649551
https://pubmed.ncbi.nlm.nih.gov/35649551
Autor:
F. Patrick Ross, Yingzhen Niu, Ilana L. Brito, Gang Ji, Theresa T. Lu, Rowan Callahan, Xu Yang, Susan Chyou, Christopher J. Hernandez, Thomas M. Li, Alberto V. Carli, Arvinth S. Sethuraman, Mathias P.G. Bostrom, Marysol Luna, Matthew B Shirley, Joseph Koressel, Michael W Fields
Publikováno v:
Clin Orthop Relat Res
Periprosthetic joint infection (PJI) is one of the most devastating complications of total joint arthroplasty. Given the mortality and morbidity associated with PJI and the challenges in treating it, there has been increased interest in risk factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4cfa042824bfba7cf335687f8443cd
https://pubmed.ncbi.nlm.nih.gov/33605632
https://pubmed.ncbi.nlm.nih.gov/33605632
Publikováno v:
Abstracts.
Background Proper function of lymphatic vessels is needed to limit the magnitude and duration of tissue inflammation, and in direct regulation of immune cell activity. Inflammatory states such as rheumatoid arthritis and psoriasis are associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51e7e5b35b926a602195439ccdb2961e
https://doi.org/10.1136/lupus-2019-lsm.109
https://doi.org/10.1136/lupus-2019-lsm.109
Autor:
Robert Spiera, Robert Lafyatis, Jessica K. Gordon, Scott A. Rodeo, Dragos C. Dasoveanu, Jennifer J. Chia, Cynthia M. Magro, Tong Zhu, Nancy H. Ruddle, Camila B. Carballo, Timothy E. McGraw, Sha Tian, Theresa T. Lu, Jeffrey L. Browning, Susan Chyou
Publikováno v:
Journal of Clinical Investigation. 126:4331-4345
Scleroderma is a group of skin-fibrosing diseases for which there are no effective treatments. A feature of the skin fibrosis typical of scleroderma is atrophy of the dermal white adipose tissue (DWAT). Adipose tissue contains adipose-derived mesench
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6408edac5e41973037850ff9eeab89
https://doi.org/10.1172/jci85740
https://doi.org/10.1172/jci85740
Autor:
Carl P. Blobel, William D. Shipman, Robert R. Clancy, Cynthia M. Magro, Sneh Sharma, Babak J. Mehrara, Susan Chyou, Peter M. Izmirly, Tania Pannellini, Richard D. Granstein, Jane E. Salmon, Eric G. Pamer, Michelle A. Lowes, Anusha Ramanathan, James W. Young, Dragos C. Dasoveanu, Theresa T. Lu, Daniel H. Kaplan, Xiaoping Qing
Publikováno v:
Science translational medicine. 10(454)
Photosensitivity, or skin sensitivity to ultraviolet radiation (UVR), is a feature of lupus erythematosus and other autoimmune and dermatologic conditions, but the mechanistic underpinnings are poorly understood. We identify a Langerhans cell (LC)–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd16b00969ecd1fa5285dd3f7098867
https://pubmed.ncbi.nlm.nih.gov/30111646
https://pubmed.ncbi.nlm.nih.gov/30111646
Autor:
Carl P. Blobel, Richard D. Granstein, T.T. Lu, Michelle A. Lowes, William D. Shipman, Daniel H. Kaplan, Cynthia M. Magro, Susan Chyou
Publikováno v:
Journal of Investigative Dermatology. 139:S110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2108471a1228bf4ed042dc1c038c9fee
https://doi.org/10.1016/j.jid.2019.03.718
https://doi.org/10.1016/j.jid.2019.03.718
Publikováno v:
Trends in immunology. 37(11)
During normal and pathologic immune responses, lymph nodes can swell considerably. The lymph node vascular–stromal compartment supports and regulates the developing immune responses and undergoes dynamic expansion and remodeling. Recent studies hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb72d6458c0db5248d0dd5d5869e4c2f
https://pubmed.ncbi.nlm.nih.gov/27638128
https://pubmed.ncbi.nlm.nih.gov/27638128
Autor:
Susan Chyou, Eric H. Ekland, Theresa T. Lu, Sha Tian, Te-Chen Jenny Tzeng, April C. Carpenter, Michael Michaud, Joseph A. Madri
Publikováno v:
The Journal of Immunology. 181:3887-3896
The lymph node vasculature is essential to immune function, but mechanisms regulating lymph node vascular maintenance and growth are not well understood. Vascular endothelial growth factor (VEGF) is an important mediator of lymph node endothelial cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fe01bfd0b02c403927226e3ebf67cc
https://doi.org/10.4049/jimmunol.181.6.3887
https://doi.org/10.4049/jimmunol.181.6.3887
Autor:
Eric H. Ekland, Theresa T. Lu, Lucila M. A. Agle, Brian Webster, Regina Ruggieri, Susan Chyou
Publikováno v:
The Journal of Experimental Medicine
Lymph nodes grow rapidly and robustly at the initiation of an immune response, and this growth is accompanied by growth of the blood vessels. Although the vessels are critical for supplying nutrients and for controlling cell trafficking, the regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03bd6c062d6f83b1f29ca05a06694c05
https://doi.org/10.1084/jem.20052272
https://doi.org/10.1084/jem.20052272