Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Susan Christman Croce"'
Autor:
Lo Jennifer Rebecca, Terrance H. Andree, Deborah Ann Evrard, Adam D. Shilling, Nicole T. Hatzenbuhler, Gary Paul Stack, Qian Lin, Deborah L. Smith, Megan Tran, Jeannette Golembieski, P J Mitchell, Lee E. Schechter, Chad E. Beyer, Dahui Zhou, Christine Huselton, Margaret Lai, Geoffrey Hornby, Boyd L. Harrison, Susan Christman Croce, Amedeo Arturo Failli, Soo Y. Yi
Publikováno v:
Journal of medicinal chemistry. 52(15)
On the basis of the previously reported clinical candidate, SSA-426 (1), a series of related 2-piperazin-1-ylquinoline derivatives 3-16 were synthesized and evaluated as dual-acting serotonin (5-HT) reuptake inhibitors and 5-HT1A receptor antagonists
Autor:
John Considine, William DeMaio, Eugene John Trybulski, Kadum Ali, Jian Qi, David Cochran, Lynne Lihotz, Albert John Molinari, Jehan F. Bagli, Susan Christman Croce
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(21)
Small molecule agonists and antagonists of the V(2)-vasopressin receptor have been discovered and have undergone clinical trials. In conjunction with these discovery programs, the synthesis and biological testing of various metabolites associated wit