Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susan C. Schwerin"'
Autor:
Elizabeth B. Hutchinson, Anakaren Romero-Lozano, Hannah R. Johnson, Andrew K. Knutsen, Asamoah Bosomtwi, Alexandru Korotcov, Anandakumar Shunmugavel, Sarah G. King, Susan C. Schwerin, Sharon L. Juliano, Bernard J. Dardzinski, Carlo Pierpaoli
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2022)
Pre-clinical models of traumatic brain injury (TBI) have been the primary experimental tool for understanding the potential mechanisms and cellular alterations that follow brain injury, but the human relevance and translational value of these models
Externí odkaz:
https://doaj.org/article/98e6f8c5f3c548deafef3afd4f87b7c7
Autor:
Dan Benjamini, Elizabeth B. Hutchinson, Michal E. Komlosh, Courtney J. Comrie, Susan C. Schwerin, Guofeng Zhang, Carlo Pierpaoli, Peter J. Basser
Publikováno v:
NeuroImage, Vol 221, Iss , Pp 117195- (2020)
We describe a practical two-dimensional (2D) diffusion MRI framework to deliver specificity and improve sensitivity to axonal injury in the spinal cord. This approach provides intravoxel distributions of correlations of water mobilities in orthogonal
Externí odkaz:
https://doaj.org/article/42f7d169717c4625804b2859b7aa2a8e
Autor:
Elizabeth B. Hutchinson, Susan C. Schwerin, Kryslaine L. Radomski, Neda Sadeghi, Michal E. Komlosh, M. O. Irfanoglu, Sharon L. Juliano, Carlo Pierpaoli
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Mild traumatic brain injury (mTBI) is highly prevalent but lacks both research tools with adequate sensitivity to detect cellular alterations that accompany mild injury and pre-clinical models that are able to robustly mimic hallmark features of huma
Externí odkaz:
https://doaj.org/article/73b44fcda6b344069f99496c910cfe81
Publikováno v:
Behavioral Neuroscience. 136:330-345
As the smallest mammal with a gyrencephalic cerebral cortex, ferrets are becoming increasingly important animal models to study neurological disorders. In order for them to be optimally used, typical behavioral measurements are highly desirable. To a
Autor:
Susan C. Schwerin, Daniel P. Perl, Sharon L. Juliano, Mitali Chatterjee, Francis T. Djankpa, Elizabeth B. Hutchinson, Joseph T. McCabe, Regina C. Armstrong
Publikováno v:
J Neuropathol Exp Neurol
Blast exposures are a hallmark of contemporary military conflicts. We need improved preclinical models of blast traumatic brain injury for translation of pharmaceutical and therapeutic protocols. Compared with rodents, the ferret brain is larger, has
Autor:
Peter J. Basser, Guofeng Zhang, Courtney J. Comrie, Dan Benjamini, Carlo Pierpaoli, Susan C. Schwerin, Elizabeth B. Hutchinson, Michal E. Komlosh
Publikováno v:
NeuroImage
NeuroImage, Vol 221, Iss, Pp 117195-(2020)
NeuroImage, Vol 221, Iss, Pp 117195-(2020)
We describe a practical two-dimensional (2D) diffusion MRI framework to deliver specificity and improve sensitivity to axonal injury in the spinal cord. This approach provides intravoxel distributions of correlations of water mobilities in orthogonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b7f9465b8e2c3bbd3cd5414f31ad0c
https://doi.org/10.1101/2020.05.04.074856
https://doi.org/10.1101/2020.05.04.074856
Autor:
Sharon L. Juliano, Elizabeth B. Hutchinson, Mitali Chatterjee, Kryslaine L. Radomski, Aminat O. Imam-Fulani, Susan C. Schwerin, Carlo Pierpaoli
Publikováno v:
Journal of Neuroscience Research. 96:556-572
White matter damage is an important consequence of traumatic brain injury (TBI) in humans. Unlike rodents, ferrets have a substantial amount of white matter and a gyrencephalic brain; therefore, they may represent an ideal small mammal model to study
Autor:
Alexandru V. Avram, M. Okan Irfanoglu, Carlo Pierpaoli, Evren Özarslan, Michal E. Komlosh, Sharon L. Juliano, Alan S. Barnett, Susan C. Schwerin, C. Guan Koay, Elizabeth B. Hutchinson
Publikováno v:
Magnetic Resonance in Medicine. 78:1767-1780
Purpose This study was a systematic evaluation across different and prominent diffusion MRI models to better understand the ways in which scalar metrics are influenced by experimental factors, including experimental design (diffusion-weighted imaging
Autor:
Carlo Pierpaoli, Elizabeth B. Hutchinson, Kryslaine L. Radomski, M. O. Irfanoglu, Susan C. Schwerin, Sharon L. Juliano
Publikováno v:
Shock (Augusta, Ga.)
During the acute time period following traumatic brain injury (TBI), noninvasive brain imaging tools such as magnetic resonance imaging (MRI) can provide important information about the clinical and pathological features of the injury and may help pr
Autor:
Kapinga P. Ngalula, Carlo Pierpaoli, Elizabeth B. Hutchinson, Kryslaine L. Radomski, Susan C. Schwerin, Sharon L. Juliano
Publikováno v:
Journal of neuroscience methods. 285
Background Although rodent TBI studies provide valuable information regarding the effects of injury and recovery, an animal model with neuroanatomical characteristics closer to humans may provide a more meaningful basis for clinical translation. The