Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Susan C. Olson"'
Publikováno v:
jcvm. 1:1-5
Chronic inflammation is implicated in the etiology of Cardiovascular Disease (CVD), the leading cause of death among men and women. Accordingly, the discovery of inflammation biomarkers, identification of agents with anti-inflammation properties, and
Publikováno v:
Annals of the New York Academy of Sciences. 1290:30-36
Coronary heart disease (CHD) is a leading cause of death in many developed countries. Evidence has long implicated endothelial injury and inflammation as apical events in the pathogenesis of atherosclerosis, the primary cause of CHD. Numerous risk fa
Autor:
Joseph D Etlinger, Jing Huang, Reza Farahani, Koko Murakami, Hong Peng, Susan C. Olson, Rajamma Mathew
Publikováno v:
Experimental Biology and Medicine. 235:805-813
Reduced bone morphogenetic protein (BMP) receptor (BMPR) expression and BMP signaling have been implicated in vascular cell proliferation and remodeling associated with pulmonary arterial hypertension (PAH). The low penetrance of the BMPR II disease
Autor:
Sachin A. Gupte, Lioubov Kouznestova, Shimran George, Thomas H. Hintze, Pawel M. Kaminski, Rajamma Mathew, Susan C. Olson, Michael S. Wolin
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 296:H1048-H1057
Protein kinase C (PKC) stimulation of NAD(P)H oxidases (Nox) is an important component of multiple vascular disease processes; however, the relationship between oxidase activation and the regulation of vascular smooth muscle contraction by PKC remain
Src Kinase Mediates Angiotensin II–Dependent Increase in Pulmonary Endothelial Nitric Oxide Synthase
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 31:365-372
We have previously demonstrated that angiotensin II (Ang II) stimulates nitric oxide (NO) production in bovine pulmonary artery endothelial cells (BPAECs) by increasing NO synthase (NOS) expression via the type 2 receptor. The purpose of this study w
Autor:
Susan C. Olson, Xinmei Li, Richard A. Oeckler, Frank Traganos, Litong Du, T. Burke-Wolin, Xiangmin Zhao
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 287:L559-L568
We previously reported that angiotensin II stimulates an increase in nitric oxide production in pulmonary artery endothelial cells. The aims of this study were to determine which receptor subtype mediates the angiotensin II-dependent increase in nitr
Publikováno v:
Surgery. 126:443-449
Background: C-fos and c-jun are 2 immediate early genes that have been implicated in the stimulation of vascular smooth muscle cell proliferation and migration. In previous experiments in our laboratory with a rat vein graft model a 2- to 3-fold incr
Publikováno v:
International Journal of Cancer. 78:53-61
We previously reported that all-trans retinoic acid (RA) and fenretinide (4HPR) suppress HL-60 leukemia cell growth and cause partial cell arrest in the G1-to-S phase. Moreover, 4HPR but not RA induces apoptosis in HL-60 cells. To investigate further
Publikováno v:
Annals of the New York Academy of Sciences. 1290
Coronary heart disease (CHD) is a leading cause of death in many developed countries. Evidence has long implicated endothelial injury and inflammation as apical events in the pathogenesis of atherosclerosis, the primary cause of CHD. Numerous risk fa
Autor:
Susan C. Olson, J. David Lambeth
Publikováno v:
Chemistry and Physics of Lipids. 80:3-19
Neutrophils play a major role host defense against invading microbes. Recent studies have emphasized the importance of the phospholipase D (PLD) in the signalling cascade leading to neutrophil activation. Phospholipase D catalyzes the hydrolysis of p