Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Susan C J Sumner"'
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
GoalBody mass index (BMI) in early pregnancy is a critical risk factor for hypertensive disorders of pregnancy (HDP). The pathobiology of the interplay between BMI and HDP is not fully understood and represents the focus of this investigation.Methods
Externí odkaz:
https://doaj.org/article/7a1a558e3133463f9d12e3dd9c9749bb
Autor:
Emily M. J. Fennell, Lucas J. Aponte-Collazo, Wimal Pathmasiri, Blake R. Rushing, Natalie K. Barker, Megan C. Partridge, Yuan-Yuan Li, Cody A. White, Yoshimi E. Greer, Laura E. Herring, Stanley Lipkowitz, Susan C. J. Sumner, Edwin J. Iwanowicz, Lee M. Graves
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
ClpP activators ONC201 and related small molecules (TR compounds, Madera Therapeutics), have demonstrated significant anti-cancer potential in vitro and in vivo studies, including clinical trials for refractory solid tumors. Though progress has been
Externí odkaz:
https://doaj.org/article/8ff4ea8f38e048409bf256e5266ae0c6
Autor:
David H. Lynch, Blake R. Rushing, Wimal Pathmasiri, Susan McRitchie, Dakota J. Batchek, Curtis L. Petersen, Danae C. Gross, Susan C. J. Sumner, John A. Batsis
Publikováno v:
Metabolites, Vol 13, Iss 7, p 853 (2023)
Caloric restriction and aerobic and resistance exercise are safe and effective lifestyle interventions for achieving weight loss in the obese older population (>65 years) and may improve physical function and quality of life. However, individual resp
Externí odkaz:
https://doaj.org/article/f2fb8ea670b0426b9b692d9ee1fed06b
Autor:
Reza Ghanbari, Yuanyuan Li, Wimal Pathmasiri, Susan McRitchie, Arash Etemadi, Jonathan D. Pollock, Hossein Poustchi, Afarin Rahimi-Movaghar, Masoumeh Amin-Esmaeili, Gholamreza Roshandel, Amaneh Shayanrad, Behrouz Abaei, Reza Malekzadeh, Susan C. J. Sumner
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Opioid use disorder (OUD) is diagnosed using the qualitative criteria defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Diagnostic biomarkers for OUD do not currently exist. Our study focused on dev
Externí odkaz:
https://doaj.org/article/11853b79c46c4b648fd605f2499ea286
Autor:
Yuan-Yuan Li, Reza Ghanbari, Wimal Pathmasiri, Susan McRitchie, Hossein Poustchi, Amaneh Shayanrad, Gholamreza Roshandel, Arash Etemadi, Jonathan D. Pollock, Reza Malekzadeh, Susan C. J. Sumner
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
Objective: Over 50 million people worldwide are estimated to use opioids, of which ~30 million use opiates (opium and its derivatives). Use of opiates has been associated with a variety of adverse complications such as neurological and behavioral out
Externí odkaz:
https://doaj.org/article/d1278c248bb145ff8bf83a0e7118369d
Publikováno v:
Metabolites, Vol 12, Iss 2, p 168 (2022)
Dysregulation of cellular metabolism is now a well-recognized hallmark of cancer. Studies investigating the metabolic features of cancer cells have shed new light onto processes in cancer cell biology and have identified many potential novel treatmen
Externí odkaz:
https://doaj.org/article/7d8fda75cfd2496e90b386b027738710
Publikováno v:
Metabolites; Volume 12; Issue 2; Pages: 168
Dysregulation of cellular metabolism is now a well-recognized hallmark of cancer. Studies investigating the metabolic features of cancer cells have shed new light onto processes in cancer cell biology and have identified many potential novel treatmen
Autor:
Herman L. Freeman, Saroja Voruganti, Baba B. Mass, Susan McRitchie, Delisha A. Stewart, Brea Nance, Wimal Pathmasiri, Yuanyuan Li, Susan C J Sumner
Publikováno v:
Cancer Research. 81:2355-2355
Genetic polymorphisms associated with drug metabolism can significantly impair chemotherapeutic efficacy. Some African American women have poor treatment response to taxane-based chemotherapy drugs, which are widely used to treat breast cancer (BCa).
Autor:
Timothy R, Fennell, Ninell P, Mortensen, Sherry R, Black, Rodney W, Snyder, Keith E, Levine, Eric, Poitras, James M, Harrington, Christopher J, Wingard, Nathan A, Holland, Wimal, Pathmasiri, Susan C J, Sumner
Publikováno v:
Journal of applied toxicology : JAT. 37(5)
Here is presented a comprehensive investigation of the distribution of polyvinylpyrrolidone (PVP)-stabilized AgNP (20 or 110 nm) in pregnant rats after a single injection or oral gavage dose. The biological impacts of AgNP exposure were evaluated by
Autor:
Rodney W, Snyder, Timothy R, Fennell, Christopher J, Wingard, Ninell P, Mortensen, Nathan A, Holland, Jonathan H, Shannahan, Wimal, Pathmasiri, Anita H, Lewin, Susan C J, Sumner
Publikováno v:
Journal of applied toxicology : JAT. 35(12)
A comprehensive distribution study was conducted in pregnant and lactating rats exposed to a suspension of uniformly carbon-14 labeled C60 ([(14) C(U)]C60 ). Rats were administered [(14) C(U)]C60 (~0.2 mg [(14) C(U)]C60 kg(-1) body weight) or 5% poly